Protein: VCIP1
Deubiquitinating protein VCPIP1 (EC 3.4.19.12) (Valosin-containing protein p97/p47 complex-interacting protein 1) (Valosin-containing protein p97/p47 complex-interacting protein p135) (VCP/p47 complex-interacting 135-kDa protein)

Gene: VCIP1, VCPIP1
Organism: Homo sapiens
Interactions: 154
UniProt ID: Q96JH7

Gene Ontology (top 5):
GO:0004843 - cysteine-type deubiquitinase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005788 - endoplasmic reticulum lumen
GO:0005795 - Golgi stack

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

935008

TERA
Transitional endoplasmic reticulum ATPase

9

1

Small-scale

0.972

High

508447

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

3

1

Small-scale

0.845

High

1394996

NSF1C
NSFL1 cofactor p47

4

2

Small-scale

0.686

High

1243428

CNKR3
Connector enhancer of kinase suppressor of ras 3

3

1

High-throughput

0.662

High

938127

ANM2
Protein arginine N-methyltransferase 2

3

0

High-throughput

0.638

High

1315700

DND1
Dead end protein homolog 1

3

0

High-throughput

0.638

High

1394980

MAF1
Repressor of RNA polymerase III transcription MAF1 homolog

3

0

High-throughput

0.638

High

1394184

LRCH3
DISP complex protein LRCH3

3

0

High-throughput

0.634

High

1394982

GAN
Gigaxonin

3

0

High-throughput

0.634

High

1394966

PLAT5
Phospholipase A and acyltransferase 5

3

0

High-throughput

0.629

High

1244957

FIGL1
Fidgetin-like protein 1

2

2

High-throughput

0.628

High

1394977

UBXN6
UBX domain-containing protein 6

2

1

High-throughput

0.628

High

999308

UBX2A
UBX domain-containing protein 2A

2

2

High-throughput

0.611

High

1135605

UBX2B
UBX domain-containing protein 2B

2

2

High-throughput

0.611

High

1280414

HUWE1
E3 ubiquitin-protein ligase HUWE1

2

1

High-throughput

0.611

High

1394972

WAC
WW domain-containing adapter protein with coiled-coil

2

0

Small-scale

0.603

High

350731

NOE2
Noelin-2

2

0

High-throughput

0.602

High

686854

S10A4
Protein S100-A4

2

1

High-throughput

0.601

High

891283

GSK3A
Glycogen synthase kinase-3 alpha

2

1

High-throughput

0.600

High

1394979

SPRTN
DNA-dependent metalloprotease SPRTN

2

0

Small-scale

0.598

High

351287

TTLL1
Polyglutamylase complex subunit TTLL1

2

0

High-throughput

0.585

High

1347633

NPL4
Nuclear protein localization protein 4 homolog

2

0

High-throughput

0.585

High

1369975

UFD1
Ubiquitin recognition factor in ER-associated degradation protein 1

2

0

High-throughput

0.585

High

1394965

SPTCS
Spatacsin

2

0

Small-scale

0.580

High

1386322

FAF2
FAS-associated factor 2

2

4

High-throughput

0.574

High

1394983

RNF41
E3 ubiquitin-protein ligase NRDP1

2

1

Small-scale

0.558

High

1046403

UBXN1
UBX domain-containing protein 1

1

3

High-throughput

0.536

High

1394995

FAF1
FAS-associated factor 1

1

5

High-throughput

0.536

High

943609

HUNK
Hormonally up-regulated neu tumor-associated kinase

1

0

High-throughput

0.518

High

1394990

SNTG2
Gamma-2-syntrophin

1

0

Small-scale

0.513

High

138937

USP9Y
Ubiquitin carboxyl-terminal hydrolase 9Y

1

0

High-throughput

0.513

High

158487

RFXK
DNA-binding protein RFXANK

1

0

High-throughput

0.513

High

187547

FANCA
Fanconi anemia group A protein

1

0

High-throughput

0.513

High

636881

GSTM3
Glutathione S-transferase Mu 3

1

0

High-throughput

0.513

High

833767

KDM5C
Lysine-specific demethylase 5C

1

0

High-throughput

0.513

High

886302

ARL4D
ADP-ribosylation factor-like protein 4D

1

0

High-throughput

0.513

High

996810

TBA1B
Tubulin alpha-1B chain

1

0

High-throughput

0.513

High

1041790

PPARD
Peroxisome proliferator-activated receptor delta

1

0

High-throughput

0.513

High

1060285

MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1

1

0

High-throughput

0.513

High

1110287

KCC2B
Calcium/calmodulin-dependent protein kinase type II subunit beta

1

0

High-throughput

0.513

High

1149274

NR0B2
Nuclear receptor subfamily 0 group B member 2

1

0

High-throughput

0.513

High

1151496

IKBB
NF-kappa-B inhibitor beta

1

0

High-throughput

0.513

High

1294639

CD20B
Cell division cycle protein 20 homolog B

1

0

High-throughput

0.513

High

1322856

EID3
EP300-interacting inhibitor of differentiation 3

1

0

High-throughput

0.513

High

1338625

UBP32
Ubiquitin carboxyl-terminal hydrolase 32

1

0

High-throughput

0.513

High

1349610

NT5C
5'(3')-deoxyribonucleotidase, cytosolic type

1

0

High-throughput

0.513

High

1368818

N42L2
NEDD4-binding protein 2-like 2

1

0

High-throughput

0.513

High

1369043

GGH
Gamma-glutamyl hydrolase

1

0

High-throughput

0.513

High

1383809

EFMT3
EEF1A lysine methyltransferase 3

1

0

High-throughput

0.513

High

1390469

DDX11
ATP-dependent DNA helicase DDX11

1

0

High-throughput

0.513

High

1394967

KI20B
Kinesin-like protein KIF20B

1

0

High-throughput

0.513

High

1394968

NPAS1
Neuronal PAS domain-containing protein 1

1

0

High-throughput

0.513

High

1394973

TBCD
Tubulin-specific chaperone D

1

0

High-throughput

0.513

High

1394985

JMJD4
2-oxoglutarate and iron-dependent oxygenase JMJD4

1

0

High-throughput

0.513

High

1394992

APC5
Anaphase-promoting complex subunit 5

1

0

High-throughput

0.513

High

1395002

FBX7
F-box only protein 7

1

0

High-throughput

0.513

High

122638

UBXN8
UBX domain-containing protein 8

1

3

High-throughput

0.489

High

300681

KRT37
Keratin, type I cuticular Ha7

1

1

High-throughput

0.489

High

300817

KRT38
Keratin, type I cuticular Ha8

1

1

High-throughput

0.489

High

366430

FA12
Coagulation factor XII

1

1

High-throughput

0.489

High

572950

INSRR
Insulin receptor-related protein

1

1

High-throughput

0.489

High

706263

S10A2
Protein S100-A2

1

1

High-throughput

0.489

High

1394970

KCD14
BTB/POZ domain-containing protein KCTD14

1

2

High-throughput

0.489

High

181923

SMAD9
Mothers against decapentaplegic homolog 9

1

0

High-throughput

0.486

High

913674

VAV2
Guanine nucleotide exchange factor VAV2

1

0

High-throughput

0.486

High

320752

UBXN7
UBX domain-containing protein 7

1

4

High-throughput

0.479

High

323527

TRI37
E3 ubiquitin-protein ligase TRIM37

1

1

High-throughput

0.479

High

730828

1433S
14-3-3 protein sigma

1

1

High-throughput

0.479

High

862379

YAP1
Transcriptional coactivator YAP1

1

2

High-throughput

0.479

High

891738

GSK3B
Glycogen synthase kinase-3 beta

1

1

High-throughput

0.479

High

1049663

1433F
14-3-3 protein eta

1

1

High-throughput

0.479

High

1394975

ASPC1
Tether containing UBX domain for GLUT4

1

1

High-throughput

0.479

High

1394978

WWTR1
WW domain-containing transcription regulator protein 1

1

1

High-throughput

0.479

High

319238

FCSD2
F-BAR and double SH3 domains protein 2

1

1

High-throughput

0.464

High

246864

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.458

High

247410

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

0

High-throughput

0.458

High

277394

TP4A3
Protein tyrosine phosphatase type IVA 3

1

0

High-throughput

0.458

High

459719

PROF1
Profilin-1

1

0

High-throughput

0.458

High

556284

CADH1
Cadherin-1

1

0

High-throughput

0.458

High

589423

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

711732

RABP2
Cellular retinoic acid-binding protein 2

1

0

High-throughput

0.458

High

764965

CTNB1
Catenin beta-1

1

0

High-throughput

0.458

High

790086

ZEB1
Zinc finger E-box-binding homeobox 1

1

0

Small-scale

0.458

High

953037

ACTB
Actin, cytoplasmic 1

1

0

High-throughput

0.458

High

980146

H4
Histone H4

1

0

High-throughput

0.458

High

1028341

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

Small-scale

0.458

High

1100244

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.458

High

1109988

HDAC1
Histone deacetylase 1

1

0

High-throughput

0.458

High

1135776

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

High-throughput

0.458

High

1138515

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1149351

STIL
SCL-interrupting locus protein

1

0

High-throughput

0.458

High

1229038

RNF43
E3 ubiquitin-protein ligase RNF43

1

0

High-throughput

0.458

High

1255087

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1281586

SLN11
Schlafen family member 11

1

0

High-throughput

0.458

High

1289538

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

1361997

RFFL
E3 ubiquitin-protein ligase rififylin

1

0

Small-scale

0.458

High

1363821

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

0

High-throughput

0.458

High

1394971

CNPY3
Protein canopy homolog 3

1

0

Small-scale

0.458

High

1394976

EDEM3
ER degradation-enhancing alpha-mannosidase-like protein 3

1

0

Small-scale

0.458

High

1394986

CPAP
Centrosomal P4.1-associated protein

1

0

High-throughput

0.458

High

1394988

PXMP2
Peroxisomal membrane protein 2

1

0

High-throughput

0.458

High

1394991

XPO7
Exportin-7

1

0

High-throughput

0.458

High

1394993

RCOR1
REST corepressor 1

1

0

High-throughput

0.458

High

1394994

MED23
Mediator of RNA polymerase II transcription subunit 23

1

0

High-throughput

0.458

High

1394998

FBW1A
F-box/WD repeat-containing protein 1A

1

0

High-throughput

0.458

High

1394999

ADIP
Afadin- and alpha-actinin-binding protein

1

0

High-throughput

0.458

High

412444

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.437

High

643028

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

1

High-throughput

0.437

High

1326307

NIN
Ninein

1

1

High-throughput

0.437

High

1395000

NINL
Ninein-like protein

1

1

High-throughput

0.437

High

437763

HEPS
Serine protease hepsin

1

0

High-throughput

0.426

High

613435

VINC
Vinculin

1

0

High-throughput

0.426

High

1366177

LPAR1
Lysophosphatidic acid receptor 1

1

0

High-throughput

0.426

High

1394969

TCPH
T-complex protein 1 subunit eta

1

0

High-throughput

0.426

High

628446

KLK2
Kallikrein-2

1

2

High-throughput

0.407

High

1394989

Q9NXW1
Translationally-controlled tumor protein

1

1

High-throughput

0.407

High

1394987

AT131
Endoplasmic reticulum transmembrane helix translocase

2

0

High-throughput

0.328

High

168888

PLD2
Phospholipase D2

1

0

High-throughput

0.279

Low

274840

PX11A
Peroxisomal membrane protein 11A

1

0

High-throughput

0.279

Low

298215

DCTN3
Dynactin subunit 3

1

0

High-throughput

0.279

Low

359857

DYR
Dihydrofolate reductase

1

0

High-throughput

0.279

Low

885011

DGKG
Diacylglycerol kinase gamma

1

0

High-throughput

0.279

Low

922488

CLH2
Clathrin heavy chain 2

1

0

High-throughput

0.279

Low

1063836

LG3BP
Galectin-3-binding protein

1

0

High-throughput

0.279

Low

1180655

AP5B1
AP-5 complex subunit beta-1

1

0

High-throughput

0.279

Low

1218213

ZN318
Zinc finger protein 318

1

0

High-throughput

0.279

Low

1242359

PLBL1
Phospholipase B-like 1

1

0

High-throughput

0.279

Low

1325822

D2HDH
D-2-hydroxyglutarate dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

1335842

DYHC2
Cytoplasmic dynein 2 heavy chain 1

1

0

High-throughput

0.279

Low

1340056

SVIP
Small VCP/p97-interacting protein

1

0

High-throughput

0.279

Low

1356183

NPRL2
GATOR1 complex protein NPRL2

1

0

High-throughput

0.279

Low

1358898

SEN15
tRNA-splicing endonuclease subunit Sen15

1

0

High-throughput

0.279

Low

1383647

VP33A
Vacuolar protein sorting-associated protein 33A

1

0

High-throughput

0.279

Low

1394666

MRP9
ATP-binding cassette sub-family C member 12

1

0

High-throughput

0.279

Low

1394974

DCC1
Sister chromatid cohesion protein DCC1

1

0

High-throughput

0.279

Low

1394981

VPS16
Vacuolar protein sorting-associated protein 16 homolog

1

0

High-throughput

0.279

Low

1394984

CIA2A
Cytosolic iron-sulfur assembly component 2A

1

0

High-throughput

0.279

Low

1394997

PSG11
Pregnancy-specific beta-1-glycoprotein 11

1

0

High-throughput

0.279

Low

1395001

SNX24
Sorting nexin-24

1

0

High-throughput

0.279

Low

106467

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

326603

MFN2
Mitofusin-2

1

0

High-throughput

0.249

Low

724792

METK2
S-adenosylmethionine synthase isoform type-2

1

0

Small-scale

0.249

Low

768902

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

989080

AP2B1
AP-2 complex subunit beta

1

0

High-throughput

0.249

Low

1097867

STX5
Syntaxin-5

1

0

Small-scale

0.249

Low

1211756

UBX11
UBX domain-containing protein 11

1

0

High-throughput

0.249

Low

1241929

FBX42
F-box only protein 42

1

0

High-throughput

0.249

Low

1249121

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

1352345

RHBL4
Rhomboid-related protein 4

1

0

High-throughput

0.249

Low

1390394

EDC3
Enhancer of mRNA-decapping protein 3

1

0

High-throughput

0.249

Low

1391158

BICD1
Protein bicaudal D homolog 1

1

0

High-throughput

0.249

Low

1070451

ZNFS1
Putative uncharacterized protein ZNF252P-AS1

1

0

High-throughput

0.232

Low

1325785

FXL16
F-box/LRR-repeat protein 16

1

0

High-throughput

0.232

Low

1340606

SMS2
Phosphatidylcholine:ceramide cholinephosphotransferase 2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025