Protein: ACD
Adrenocortical dysplasia protein homolog (POT1 and TIN2-interacting protein)

Gene: ACD
Organism: Homo sapiens
Interactions: 89
UniProt ID: Q96AP0

Gene Ontology (top 5):
GO:0000723 - telomere maintenance
GO:0000781 - chromosome, telomeric region
GO:0000783 - nuclear telomere cap complex
GO:0001501 - skeletal system development
GO:0001655 - urogenital system development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1383369

TINF2
TERF1-interacting nuclear factor 2

14

1

Small-scale

0.765

High

1383378

POTE1
Protection of telomeres protein 1

13

3

Small-scale

0.764

High

928511

TERF1
Telomeric repeat-binding factor 1

7

3

Small-scale

0.746

High

1383379

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

5

1

Small-scale

0.720

High

1149955

TERF2
Telomeric repeat-binding factor 2

4

3

Small-scale

0.683

High

1371586

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

2

0

High-throughput

0.598

High

1121486

KEAP1
Kelch-like ECH-associated protein 1

2

0

High-throughput

0.576

High

457898

INVO
Involucrin

1

1

High-throughput

0.573

High

1383383

CHIP
E3 ubiquitin-protein ligase CHIP

1

1

High-throughput

0.573

High

1124682

SRC8
Src substrate cortactin

1

2

High-throughput

0.552

High

1383380

AIPL1
Aryl-hydrocarbon-interacting protein-like 1

1

1

High-throughput

0.552

High

1383384

NUDC
Nuclear migration protein nudC

1

1

High-throughput

0.552

High

134112

IPO5
Importin-5

1

0

High-throughput

0.549

High

226990

ENSA
Alpha-endosulfine

1

0

High-throughput

0.549

High

1380068

FBXW7
F-box/WD repeat-containing protein 7

1

0

Small-scale

0.549

High

1383385

SBDS
Ribosome maturation protein SBDS

1

0

High-throughput

0.549

High

537665

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.536

High

315854

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.529

High

347857

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.529

High

468673

HS90B
Heat shock protein HSP 90-beta

1

0

High-throughput

0.529

High

476772

RSSA
Small ribosomal subunit protein uS2

1

0

High-throughput

0.529

High

479159

ENOG
Gamma-enolase

1

0

High-throughput

0.529

High

953020

ACTB
Actin, cytoplasmic 1

1

0

High-throughput

0.529

High

1032521

PFKAP
ATP-dependent 6-phosphofructokinase, platelet type

1

0

High-throughput

0.529

High

1293557

F131B
Protein FAM131B

1

0

High-throughput

0.529

High

731526

STIP1
Stress-induced-phosphoprotein 1

1

1

High-throughput

0.523

High

1118552

TBB2A
Tubulin beta-2A chain

1

1

High-throughput

0.523

High

1383382

DBNL
Drebrin-like protein

1

3

High-throughput

0.523

High

558317

XRCC6
X-ray repair cross-complementing protein 6

1

0

High-throughput

0.518

High

1383375

STN1
CST complex subunit STN1

1

1

Small-scale

0.515

High

1370049

RENT1
Regulator of nonsense transcripts 1

1

0

Small-scale

0.512

High

276709

FKBP6
Inactive peptidyl-prolyl cis-trans isomerase FKBP6

1

1

High-throughput

0.504

High

997456

TBB4B
Tubulin beta-4B chain

1

1

High-throughput

0.504

High

1133140

LASP1
LIM and SH3 domain protein 1

1

2

High-throughput

0.504

High

1153728

TOM34
Mitochondrial import receptor subunit TOM34

1

1

High-throughput

0.504

High

1160716

DREB
Drebrin

1

1

High-throughput

0.504

High

1358082

NUDC2
NudC domain-containing protein 2

1

1

High-throughput

0.504

High

1380804

TRI63
E3 ubiquitin-protein ligase TRIM63

1

1

High-throughput

0.494

High

1383372

TRI55
Tripartite motif-containing protein 55

1

1

High-throughput

0.494

High

1088952

TP53B
TP53-binding protein 1

1

1

High-throughput

0.479

High

1129684

MDC1
Mediator of DNA damage checkpoint protein 1

1

1

High-throughput

0.479

High

162956

TERT
Telomerase reverse transcriptase

1

0

Small-scale

0.458

High

173187

XPO1
Exportin-1

1

0

High-throughput

0.458

High

799375

BRCA1
Breast cancer type 1 susceptibility protein

1

0

High-throughput

0.458

High

980107

H4
Histone H4

1

0

High-throughput

0.458

High

1383376

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

761474

HS71L
Heat shock 70 kDa protein 1-like

1

1

High-throughput

0.445

High

1217675

AXA81
Annexin A8-like protein 1

1

1

High-throughput

0.439

High

568970

ANXA8
Annexin A8

1

1

High-throughput

0.437

High

575180

IDE
Insulin-degrading enzyme

1

0

High-throughput

0.426

High

1335484

SEN2
tRNA-splicing endonuclease subunit Sen2

1

0

High-throughput

0.426

High

66839

RFPLA
Ret finger protein-like 4A

1

1

High-throughput

0.407

High

1358541

POF1B
Protein POF1B

2

0

High-throughput

0.328

High

295222

EIF3G
Eukaryotic translation initiation factor 3 subunit G

1

0

High-throughput

0.299

High

890674

RGS3
Regulator of G-protein signaling 3

1

0

High-throughput

0.299

High

971856

1433E
14-3-3 protein epsilon

1

0

High-throughput

0.299

High

1123267

DPYL3
Dihydropyrimidinase-related protein 3

1

0

High-throughput

0.299

High

1324838

LRC25
Leucine-rich repeat-containing protein 25

1

0

High-throughput

0.299

High

1383368

PDLI2
PDZ and LIM domain protein 2

1

0

High-throughput

0.299

High

1383370

TBCD
Tubulin-specific chaperone D

1

0

High-throughput

0.299

High

1383371

TB10A
TBC1 domain family member 10A

1

0

High-throughput

0.299

High

1383374

RBSK
Ribokinase

1

0

High-throughput

0.299

High

132941

ST1C2
Sulfotransferase 1C2

1

0

High-throughput

0.288

High

221276

DCX
Neuronal migration protein doublecortin

1

0

High-throughput

0.288

High

334354

TRI16
Tripartite motif-containing protein 16

1

0

High-throughput

0.288

High

358770

LDHA
L-lactate dehydrogenase A chain

1

0

High-throughput

0.288

High

409023

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

0

High-throughput

0.288

High

553259

KCRB
Creatine kinase B-type

1

0

High-throughput

0.288

High

660702

IF4B
Eukaryotic translation initiation factor 4B

1

0

High-throughput

0.288

High

896281

PEX5
Peroxisomal targeting signal 1 receptor

1

0

High-throughput

0.288

High

933083

ADPRH
ADP-ribosylhydrolase ARH1

1

0

High-throughput

0.288

High

1034511

TAGL
Transgelin

1

0

High-throughput

0.288

High

1059236

TISB
mRNA decay activator protein ZFP36L1

1

0

High-throughput

0.288

High

1192165

LEGL
Galectin-related protein

1

0

High-throughput

0.288

High

1244283

ZN790
Zinc finger protein 790

1

0

High-throughput

0.288

High

1275888

PAGE2
P antigen family member 2

1

0

High-throughput

0.288

High

1308053

ABC3F
DNA dC->dU-editing enzyme APOBEC-3F

1

0

High-throughput

0.288

High

1308400

ANKY2
Ankyrin repeat and MYND domain-containing protein 2

1

0

High-throughput

0.288

High

1327005

AF1L2
Actin filament-associated protein 1-like 2

1

0

High-throughput

0.288

High

1383366

PGM2
Phosphopentomutase

1

0

High-throughput

0.288

High

1383373

TRI15
E3 ubiquitin-protein ligase TRIM15

1

0

High-throughput

0.288

High

1383381

NCDN
Neurochondrin

1

0

High-throughput

0.288

High

1371824

CUL5
Cullin-5

1

0

High-throughput

0.279

Low

1383367

NTAQ1
Protein N-terminal glutamine amidohydrolase

1

0

High-throughput

0.251

Low

1146326

L2GL1
Lethal(2) giant larvae protein homolog 1

1

0

High-throughput

0.238

Low

230087

SAHH2
S-adenosylhomocysteine hydrolase-like protein 1

1

0

High-throughput

0.232

Low

379381

IGHG2
Immunoglobulin heavy constant gamma 2

1

0

High-throughput

0.232

Low

1335976

B3GL2
UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2

1

0

High-throughput

0.232

Low

1383377

CAH10
Carbonic anhydrase-related protein 10

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025