Protein: BAD
Bcl2-associated agonist of cell death (BAD) (Bcl-2-binding component 6) (Bcl-2-like protein 8) (Bcl2-L-8) (Bcl-xL/Bcl-2-associated death promoter) (Bcl2 antagonist of cell death)

Gene: BAD
Organism: Homo sapiens
Interactions: 107
UniProt ID: Q92934

Gene Ontology (top 5):
GO:0001836 - release of cytochrome c from mitochondria
GO:0005543 - phospholipid binding
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1060198

B2CL1
Bcl-2-like protein 1

40

8

Small-scale

0.995

High

522119

BCL2
Apoptosis regulator Bcl-2

12

8

Small-scale

0.982

High

1369440

B2CL2
Bcl-2-like protein 2

9

8

Small-scale

0.968

High

1060278

MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1

2

8

Small-scale

0.767

High

1158637

B2LA1
Bcl-2-related protein A1

2

8

Small-scale

0.767

High

990576

1433Z
14-3-3 protein zeta/delta

16

9

Small-scale

0.762

High

691310

1433T
14-3-3 protein theta

12

9

Small-scale

0.756

High

730812

1433S
14-3-3 protein sigma

9

9

Small-scale

0.756

High

730122

1433B
14-3-3 protein beta/alpha

10

9

Small-scale

0.754

High

728364

AKT1
RAC-alpha serine/threonine-protein kinase

7

7

Small-scale

0.749

High

1049640

1433F
14-3-3 protein eta

9

9

Small-scale

0.749

High

1060115

BAX
Apoptosis regulator BAX

2

8

Small-scale

0.737

High

966705

1433G
14-3-3 protein gamma

6

9

High-throughput

0.732

High

971850

1433E
14-3-3 protein epsilon

9

0

Small-scale

0.721

High

1096470

PAK1
Serine/threonine-protein kinase PAK 1

3

5

Small-scale

0.667

High

605771

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

3

5

Small-scale

0.646

High

791603

SYUA
Alpha-synuclein

3

1

Small-scale

0.633

High

401245

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

2

Small-scale

0.625

High

773770

ACTN2
Alpha-actinin-2

2

0

High-throughput

0.580

High

1146083

K1H1
Keratin, type I cuticular Ha1

2

0

High-throughput

0.580

High

143676

PPP6
Serine/threonine-protein phosphatase 6 catalytic subunit

2

2

High-throughput

0.571

High

334863

IPO7
Importin-7

2

2

High-throughput

0.571

High

537644

HSP7C
Heat shock cognate 71 kDa protein

2

1

High-throughput

0.571

High

600889

HSP76
Heat shock 70 kDa protein 6

2

1

High-throughput

0.571

High

651696

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

2

5

High-throughput

0.571

High

717922

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

2

1

High-throughput

0.571

High

718156

2AAB
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

2

1

High-throughput

0.571

High

994321

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

2

1

High-throughput

0.571

High

1040180

M2OM
Mitochondrial 2-oxoglutarate/malate carrier protein

2

1

High-throughput

0.571

High

1103140

2A5G
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform

2

1

High-throughput

0.571

High

1134316

IMB1
Importin subunit beta-1

2

1

High-throughput

0.571

High

1158071

2A5E
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform

2

1

High-throughput

0.571

High

1214739

ATD3B
ATPase family AAA domain-containing protein 3B

2

2

High-throughput

0.571

High

1370801

IPO9
Importin-9

2

2

High-throughput

0.571

High

1370806

ATD3A
ATPase family AAA domain-containing protein 3A

2

2

High-throughput

0.571

High

1370808

DIC
Mitochondrial dicarboxylate carrier

2

1

High-throughput

0.571

High

415763

HSPB1
Heat shock protein beta-1

2

0

High-throughput

0.547

High

471679

CY1
Cytochrome c1, heme protein, mitochondrial

2

0

High-throughput

0.547

High

531122

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

2

0

High-throughput

0.547

High

532831

CH60
60 kDa heat shock protein, mitochondrial

2

0

High-throughput

0.547

High

697609

PYR1
Multifunctional protein CAD

2

0

High-throughput

0.547

High

701883

ABCD3
ATP-binding cassette sub-family D member 3

2

0

High-throughput

0.547

High

894950

EMD
Emerin

2

0

High-throughput

0.547

High

939814

ATPK
ATP synthase F(0) complex subunit f, mitochondrial

2

0

High-throughput

0.547

High

944533

GEMI4
Gem-associated protein 4

2

0

High-throughput

0.547

High

1008272

PRKDC
DNA-dependent protein kinase catalytic subunit

2

0

High-throughput

0.547

High

1024424

S25A3
Solute carrier family 25 member 3

2

0

High-throughput

0.547

High

1066428

RBBP4
Histone-binding protein RBBP4

2

0

High-throughput

0.547

High

1095429

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

2

0

High-throughput

0.547

High

1160536

SMN
Survival motor neuron protein

2

0

High-throughput

0.547

High

1199811

AGK
Acylglycerol kinase, mitochondrial

2

0

High-throughput

0.547

High

1239899

CAVN1
Caveolae-associated protein 1

2

0

High-throughput

0.547

High

1337204

MCU
Calcium uniporter protein, mitochondrial

2

0

High-throughput

0.547

High

1339868

KNL1
Outer kinetochore KNL1 complex subunit KNL1

2

0

High-throughput

0.547

High

1368027

HDAC2
Histone deacetylase 2

2

0

High-throughput

0.547

High

1370799

HOOK2
Protein Hook homolog 2

2

0

High-throughput

0.547

High

1370803

OSBL8
Oxysterol-binding protein-related protein 8

2

0

High-throughput

0.547

High

1370809

DDX20
Probable ATP-dependent RNA helicase DDX20

2

0

High-throughput

0.547

High

1370813

TIM9
Mitochondrial import inner membrane translocase subunit Tim9

2

0

High-throughput

0.547

High

1228199

CR3L3
Cyclic AMP-responsive element-binding protein 3-like protein 3

1

1

High-throughput

0.541

High

922273

LIMK1
LIM domain kinase 1

1

3

High-throughput

0.536

High

1370804

GAN
Gigaxonin

1

1

High-throughput

0.536

High

808134

CDN1A
Cyclin-dependent kinase inhibitor 1

1

0

High-throughput

0.518

High

1121483

KEAP1
Kelch-like ECH-associated protein 1

1

0

High-throughput

0.518

High

967897

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

1

High-throughput

0.515

High

227120

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.513

High

250746

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

0

High-throughput

0.513

High

1370802

SORT
Sortilin

1

0

High-throughput

0.513

High

1370810

NDUAC
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12

1

0

High-throughput

0.513

High

521401

ARAF
Serine/threonine-protein kinase A-Raf

1

2

Small-scale

0.501

High

541046

PIM1
Serine/threonine-protein kinase pim-1

1

4

Small-scale

0.501

High

578527

BRAF
Serine/threonine-protein kinase B-raf

1

2

Small-scale

0.501

High

835723

KPCI
Protein kinase C iota type

1

5

Small-scale

0.501

High

1148371

KS6A1
Ribosomal protein S6 kinase alpha-1

1

6

Small-scale

0.501

High

1370807

PIM2
Serine/threonine-protein kinase pim-2

1

1

Small-scale

0.501

High

422780

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.493

High

457119

CAN1
Calpain-1 catalytic subunit

1

0

High-throughput

0.493

High

163149

CHK1
Serine/threonine-protein kinase Chk1

1

0

Small-scale

0.480

High

239382

BNI3L
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like

1

0

Small-scale

0.480

High

219651

B2L11
Bcl-2-like protein 11

1

0

Small-scale

0.479

High

279197

ULK1
Serine/threonine-protein kinase ULK1

1

2

Small-scale

0.479

High

603324

KPCA
Protein kinase C alpha type

1

4

High-throughput

0.479

High

1035009

KPCE
Protein kinase C epsilon type

1

3

Small-scale

0.479

High

1143079

KPCD1
Serine/threonine-protein kinase D1

1

4

Small-scale

0.479

High

732375

PRDX2
Peroxiredoxin-2

1

0

High-throughput

0.460

High

1225902

STEA3
Metalloreductase STEAP3

1

0

High-throughput

0.460

High

934952

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

987825

GRB2
Growth factor receptor-bound protein 2

1

0

High-throughput

0.458

High

1126733

BECN1
Beclin-1

1

0

Small-scale

0.458

High

1327914

CISD2
CDGSH iron-sulfur domain-containing protein 2

1

0

Small-scale

0.458

High

1370798

BAD
Bcl2-associated agonist of cell death

1

0

High-throughput

0.458

High

1370812

CBY1
Protein chibby homolog 1

1

0

High-throughput

0.458

High

287717

KS6A5
Ribosomal protein S6 kinase alpha-5

1

5

Small-scale

0.457

High

1370805

WNK1
Serine/threonine-protein kinase WNK1

1

2

High-throughput

0.457

High

1258531

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

1

High-throughput

0.407

High

1275329

APTX
Aprataxin

2

0

High-throughput

0.328

High

283325

ERLN1
Erlin-1

2

0

High-throughput

0.298

High

316936

MTA2
Metastasis-associated protein MTA2

2

0

High-throughput

0.298

High

337788

SGPL1
Sphingosine-1-phosphate lyase 1

2

0

High-throughput

0.298

High

1219867

OBI1
ORC ubiquitin ligase 1

2

0

High-throughput

0.298

High

1370006

GSLG1
Golgi apparatus protein 1

2

0

High-throughput

0.298

High

1370811

AKP8L
A-kinase anchor protein 8-like

2

0

High-throughput

0.298

High

1033114

EWS
RNA-binding protein EWS

1

0

High-throughput

0.282

High

954981

S10AA
Protein S100-A10

1

0

Small-scale

0.275

Low

964405

SUMO2
Small ubiquitin-related modifier 2

1

0

High-throughput

0.265

Low

1370800

GIMA5
GTPase IMAP family member 5

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025