Protein: TNNT1
Troponin T, slow skeletal muscle (TnTs) (Slow skeletal muscle troponin T) (sTnT)

Gene: TNNT1
Organism: Homo sapiens
Interactions: 89
UniProt ID: P13805

Gene Ontology (top 5):
GO:0003009 - skeletal muscle contraction
GO:0005523 - tropomyosin binding
GO:0005829 - cytosol
GO:0005861 - troponin complex
GO:0014883 - transition between fast and slow fiber

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

482826

TPM1
Tropomyosin alpha-1 chain

4

4

Small-scale

0.919

High

447658

TPM3
Tropomyosin alpha-3 chain

2

4

High-throughput

0.817

High

568534

TNNT1
Troponin T, slow skeletal muscle

2

4

High-throughput

0.815

High

568538

TNNI1
Troponin I, slow skeletal muscle

2

4

High-throughput

0.783

High

568542

TNNT2
Troponin T, cardiac muscle

2

4

High-throughput

0.783

High

568543

TNNI2
Troponin I, fast skeletal muscle

2

4

High-throughput

0.783

High

568600

NINL
Ninein-like protein

1

1

High-throughput

0.698

High

568560

NF2L2
Nuclear factor erythroid 2-related factor 2

4

0

High-throughput

0.668

High

568558

KGP1
cGMP-dependent protein kinase 1

2

1

Small-scale

0.649

High

568570

ARMC8
Armadillo repeat-containing protein 8

2

1

High-throughput

0.625

High

568552

TNNC1
Troponin C, slow skeletal and cardiac muscles

1

1

Small-scale

0.621

High

568563

Q5VU62
TPM3 protein

1

4

High-throughput

0.594

High

568550

PRS8
26S proteasome regulatory subunit 8

2

0

High-throughput

0.594

High

568568

K1C27
Keratin, type I cytoskeletal 27

2

0

High-throughput

0.580

High

568586

SDCB2
Syntenin-2

2

0

High-throughput

0.580

High

568582

CC136
Coiled-coil domain-containing protein 136

2

1

High-throughput

0.578

High

503698

SBK3
Uncharacterized serine/threonine-protein kinase SBK3

2

1

High-throughput

0.553

High

568564

K1C40
Keratin, type I cytoskeletal 40

1

0

High-throughput

0.549

High

568555

LIPA1
Liprin-alpha-1

1

1

High-throughput

0.541

High

568548

RD23A
UV excision repair protein RAD23 homolog A

1

1

High-throughput

0.536

High

568567

MAEA
E3 ubiquitin-protein transferase MAEA

1

2

High-throughput

0.536

High

568572

GID4
Glucose-induced degradation protein 4 homolog

1

1

High-throughput

0.536

High

568584

CK5P2
CDK5 regulatory subunit-associated protein 2

1

1

High-throughput

0.536

High

568592

RMD5A
E3 ubiquitin-protein transferase RMND5A

1

2

High-throughput

0.536

High

568577

TRI63
E3 ubiquitin-protein ligase TRIM63

2

1

Small-scale

0.526

High

568595

MO4L1
Mortality factor 4-like protein 1

1

2

High-throughput

0.523

High

568544

FXR2
RNA-binding protein FXR2

1

0

High-throughput

0.518

High

568589

RNF41
E3 ubiquitin-protein ligase NRDP1

1

0

High-throughput

0.513

High

568546

HAP1
Huntingtin-associated protein 1

1

2

High-throughput

0.508

High

279272

TULP3
Tubby-related protein 3

1

1

High-throughput

0.494

High

568573

CLIP4
CAP-Gly domain-containing linker protein 4

1

1

High-throughput

0.494

High

568569

TLK2
Serine/threonine-protein kinase tousled-like 2

1

1

High-throughput

0.489

High

568587

TARA
TRIO and F-actin-binding protein

1

1

High-throughput

0.489

High

568598

TLK1
Serine/threonine-protein kinase tousled-like 1

1

1

High-throughput

0.489

High

323830

SC31A
Protein transport protein Sec31A

1

0

High-throughput

0.486

High

440329

FYN
Tyrosine-protein kinase Fyn

1

0

High-throughput

0.486

High

468019

HS90B
Heat shock protein HSP 90-beta

1

0

High-throughput

0.486

High

474441

VIME
Vimentin

1

0

High-throughput

0.486

High

568537

DDX5
Probable ATP-dependent RNA helicase DDX5

1

0

High-throughput

0.486

High

568539

EF1G
Elongation factor 1-gamma

1

0

High-throughput

0.486

High

568545

UB2D1
Ubiquitin-conjugating enzyme E2 D1

1

0

High-throughput

0.486

High

568549

SYMC
Methionine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.486

High

568565

LARP1
La-related protein 1

1

0

High-throughput

0.486

High

568566

BL1S2
Biogenesis of lysosome-related organelles complex 1 subunit 2

1

0

High-throughput

0.486

High

568575

ZC3HF
Zinc finger CCCH domain-containing protein 15

1

0

High-throughput

0.486

High

568576

KAT5
Histone acetyltransferase KAT5

1

0

High-throughput

0.486

High

568578

OSBP2
Oxysterol-binding protein 2

1

0

High-throughput

0.486

High

568597

NAGK
N-acetyl-D-glucosamine kinase

1

0

High-throughput

0.486

High

568599

FAF1
FAS-associated factor 1

1

0

High-throughput

0.486

High

176755

NACAD
NAC-alpha domain-containing protein 1

1

1

High-throughput

0.464

High

568590

ZN768
Zinc finger protein 768

1

1

High-throughput

0.464

High

446603

NPM
Nucleophosmin

1

0

High-throughput

0.458

High

568541

PI4KA
Phosphatidylinositol 4-kinase alpha

1

1

High-throughput

0.457

High

568562

Q4LE69
Phosphatidylinositol 4-kinase alpha

1

1

High-throughput

0.439

High

568593

SMUF2
E3 ubiquitin-protein ligase SMURF2

1

0

High-throughput

0.438

High

136812

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

2

High-throughput

0.437

High

568579

JKIP2
Janus kinase and microtubule-interacting protein 2

1

1

High-throughput

0.417

High

346606

TTC4
Tetratricopeptide repeat protein 4

1

1

High-throughput

0.407

High

568553

MFGM
Lactadherin

1

1

High-throughput

0.407

High

568605

RT23
Small ribosomal subunit protein mS23

1

1

High-throughput

0.407

High

343729

LDOC1
Protein LDOC1

2

0

High-throughput

0.327

High

568594

TFP11
Tuftelin-interacting protein 11

2

0

High-throughput

0.327

High

568588

TSYL2
Testis-specific Y-encoded-like protein 2

2

0

High-throughput

0.316

High

568551

TBPL1
TATA box-binding protein-like 1

1

0

High-throughput

0.299

High

568547

MYOM2
Myomesin-2

1

0

High-throughput

0.282

High

568559

CC85B
Coiled-coil domain-containing protein 85B

1

0

High-throughput

0.282

High

568580

ZMY19
Zinc finger MYND domain-containing protein 19

1

0

High-throughput

0.282

High

568583

PKHF1
Pleckstrin homology domain-containing family F member 1

1

0

High-throughput

0.282

High

568581

MMAB
Corrinoid adenosyltransferase MMAB

1

0

High-throughput

0.279

Low

568536

H15
Histone H1.5

1

0

High-throughput

0.269

Low

567754

ONCM
Oncostatin-M

1

0

High-throughput

0.265

Low

568535

ZN250
Zinc finger protein 250

1

0

High-throughput

0.265

Low

568540

KAIN
Kallistatin

1

0

High-throughput

0.265

Low

568554

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

0

High-throughput

0.265

Low

568556

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.265

Low

568557

TRA2A
Transformer-2 protein homolog alpha

1

0

High-throughput

0.265

Low

568561

MIC60
MICOS complex subunit MIC60

1

0

High-throughput

0.265

Low

568585

SH3G3
Endophilin-A3

1

0

High-throughput

0.265

Low

568591

WDCP
WD repeat and coiled-coil-containing protein

1

0

High-throughput

0.265

Low

568596

HMGX4
HMG domain-containing protein 4

1

0

High-throughput

0.265

Low

568601

ZKSC5
Zinc finger protein with KRAB and SCAN domains 5

1

0

High-throughput

0.265

Low

568602

TMM98
Transmembrane protein 98

1

0

High-throughput

0.265

Low

568603

NSG2
Neuronal vesicle trafficking-associated protein 2

1

0

High-throughput

0.265

Low

541805

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.249

Low

568571

NUDC3
NudC domain-containing protein 3

1

0

High-throughput

0.249

Low

568604

DHRS7
Dehydrogenase/reductase SDR family member 7

1

0

High-throughput

0.249

Low

332481

CCDB1
Cyclin-D1-binding protein 1

1

0

High-throughput

0.238

Low

568574

PNMA1
Paraneoplastic antigen Ma1

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025