Protein: PYGM
Glycogen phosphorylase, muscle form (EC 2.4.1.1) (Myophosphorylase)

Gene: PYGM
Organism: Homo sapiens
Interactions: 91
UniProt ID: P11217

Gene Ontology (top 5):
GO:0000166 - nucleotide binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005977 - glycogen metabolic process
GO:0005980 - glycogen catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

539507

PYGB
Glycogen phosphorylase, brain form

4

8

High-throughput

0.894

High

446119

PYGL
Glycogen phosphorylase, liver form

2

8

High-throughput

0.783

High

225524

AAKB2
5'-AMP-activated protein kinase subunit beta-2

4

1

High-throughput

0.705

High

539626

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

0

High-throughput

0.601

High

539597

TLE3
Transducin-like enhancer protein 3

2

1

High-throughput

0.574

High

539611

PPR3B
Protein phosphatase 1 regulatory subunit 3B

1

6

High-throughput

0.541

High

539634

TRI54
Tripartite motif-containing protein 54

1

6

High-throughput

0.541

High

539635

TRI55
Tripartite motif-containing protein 55

1

7

High-throughput

0.541

High

539638

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

1

3

High-throughput

0.541

High

539584

S10A1
Protein S100-A1

1

0

Small-scale

0.537

High

276663

FKBP6
Inactive peptidyl-prolyl cis-trans isomerase FKBP6

1

2

High-throughput

0.536

High

329504

STBD1
Starch-binding domain-containing protein 1

1

2

High-throughput

0.536

High

348950

LATS1
Serine/threonine-protein kinase LATS1

1

4

High-throughput

0.536

High

539615

DDHD1
Phospholipase DDHD1

1

1

High-throughput

0.536

High

539624

GASP2
G-protein coupled receptor-associated sorting protein 2

1

2

High-throughput

0.536

High

539644

SPAST
Spastin

1

3

High-throughput

0.536

High

539645

HSPB8
Heat shock protein beta-8

1

2

High-throughput

0.536

High

270884

CLAP2
CLIP-associating protein 2

1

0

High-throughput

0.518

High

303395

SRP72
Signal recognition particle subunit SRP72

1

0

High-throughput

0.518

High

385397

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.518

High

539588

DYN2
Dynamin-2

1

0

High-throughput

0.518

High

539594

IGBP1
Immunoglobulin-binding protein 1

1

0

High-throughput

0.518

High

539606

MYOME
Myomegalin

1

0

High-throughput

0.518

High

539616

ARI1B
AT-rich interactive domain-containing protein 1B

1

0

High-throughput

0.518

High

539618

TITIN
Titin

1

0

High-throughput

0.518

High

539627

INT4
Integrator complex subunit 4

1

0

High-throughput

0.518

High

539631

F110A
Protein FAM110A

1

0

High-throughput

0.518

High

539647

CBPC1
Cytosolic carboxypeptidase 1

1

0

High-throughput

0.518

High

539648

POMP
Proteasome maturation protein

1

0

High-throughput

0.518

High

539650

MRCKB
Serine/threonine-protein kinase MRCK beta

1

0

High-throughput

0.518

High

539636

TRI31
E3 ubiquitin-protein ligase TRIM31

1

3

High-throughput

0.515

High

539583

FPPS
Farnesyl pyrophosphate synthase

1

0

High-throughput

0.513

High

539585

TSPO
Translocator protein

1

0

High-throughput

0.513

High

539595

MECOM
Histone-lysine N-methyltransferase MECOM

1

0

High-throughput

0.513

High

539599

ARL16
ADP-ribosylation factor-like protein 16

1

0

High-throughput

0.513

High

539600

DNJC3
DnaJ homolog subfamily C member 3

1

0

High-throughput

0.513

High

539602

ARHG7
Rho guanine nucleotide exchange factor 7

1

0

High-throughput

0.513

High

539603

GLO2
Hydroxyacylglutathione hydrolase, mitochondrial

1

0

High-throughput

0.513

High

539608

DPPA3
Developmental pluripotency-associated protein 3

1

0

High-throughput

0.513

High

539612

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.513

High

539639

DSN1
Kinetochore-associated protein DSN1 homolog

1

0

High-throughput

0.513

High

539642

E41L5
Band 4.1-like protein 5

1

0

High-throughput

0.513

High

539651

SPIN1
Spindlin-1

1

0

High-throughput

0.513

High

539652

TAF6L
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L

1

0

High-throughput

0.513

High

539592

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

5

Small-scale

0.501

High

539593

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

4

Small-scale

0.501

High

539646

PACN3
Protein kinase C and casein kinase substrate in neurons protein 3

1

0

High-throughput

0.493

High

521513

H14
Histone H1.4

1

1

High-throughput

0.489

High

539586

MCM5
DNA replication licensing factor MCM5

1

5

High-throughput

0.489

High

539613

LZTR1
Leucine-zipper-like transcriptional regulator 1

1

2

High-throughput

0.489

High

539614

ABTB2
Ankyrin repeat and BTB/POZ domain-containing protein 2

1

2

High-throughput

0.489

High

515670

TPC2B
Trafficking protein particle complex subunit 2B

1

1

High-throughput

0.481

High

539621

TRI63
E3 ubiquitin-protein ligase TRIM63

1

6

Small-scale

0.481

High

240590

PRKN
E3 ubiquitin-protein ligase parkin

1

4

High-throughput

0.479

High

539587

MCM2
DNA replication licensing factor MCM2

1

5

High-throughput

0.479

High

539609

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.479

High

539633

FACD2
Fanconi anemia group D2 protein

1

2

High-throughput

0.479

High

539640

PKHA4
Pleckstrin homology domain-containing family A member 4

1

4

High-throughput

0.479

High

136797

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

0

High-throughput

0.458

High

539589

BRCA2
Breast cancer type 2 susceptibility protein

1

0

Small-scale

0.458

High

539591

RS7
Small ribosomal subunit protein eS7

1

0

High-throughput

0.458

High

539596

K1C17
Keratin, type I cytoskeletal 17

1

0

High-throughput

0.458

High

539630

M3K3
Mitogen-activated protein kinase kinase kinase 3

1

0

High-throughput

0.458

High

539632

INP5K
Inositol polyphosphate 5-phosphatase K

1

0

High-throughput

0.458

High

515616

TPC2A
Trafficking protein particle complex subunit 2

1

1

High-throughput

0.457

High

346602

TTC4
Tetratricopeptide repeat protein 4

1

2

High-throughput

0.445

High

528948

TAU
Microtubule-associated protein tau

1

9

High-throughput

0.445

High

539590

SMS
Somatostatin

1

1

Small-scale

0.445

High

539607

A16L1
Autophagy-related protein 16-1

1

2

High-throughput

0.445

High

105202

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

539620

DPF3
Zinc finger protein DPF3

1

1

Small-scale

0.437

High

539598

MFGM
Lactadherin

1

0

High-throughput

0.426

High

539622

ARL8A
ADP-ribosylation factor-like protein 8A

1

0

High-throughput

0.426

High

254769

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

2

High-throughput

0.407

High

276048

NIPS2
Protein NipSnap homolog 2

1

0

High-throughput

0.282

High

539601

SGCG
Gamma-sarcoglycan

1

0

High-throughput

0.282

High

539604

ANR55
Ankyrin repeat domain-containing protein 55

1

0

High-throughput

0.279

Low

539605

TAF1B
TATA box-binding protein-associated factor RNA polymerase I subunit B

1

0

High-throughput

0.279

Low

539610

TSN33
Tetraspanin-33

1

0

High-throughput

0.279

Low

539617

RDH11
Retinol dehydrogenase 11

1

0

High-throughput

0.279

Low

539619

RT31
Small ribosomal subunit protein mS31

1

0

High-throughput

0.279

Low

539623

T4S18
Transmembrane 4 L6 family member 18

1

0

High-throughput

0.279

Low

539625

MYEOV
Myeloma-overexpressed gene protein

1

0

High-throughput

0.279

Low

539628

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

1

0

High-throughput

0.279

Low

539629

FA81B
Protein FAM81B

1

0

High-throughput

0.279

Low

539637

RSH6A
Radial spoke head protein 6 homolog A

1

0

High-throughput

0.279

Low

539641

MAGF1
Melanoma-associated antigen F1

1

0

High-throughput

0.279

Low

178601

DEGS1
Sphingolipid delta(4)-desaturase DES1

1

0

High-throughput

0.269

Low

539643

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

0

High-throughput

0.249

Low

539649

RT23
Small ribosomal subunit protein mS23

1

0

High-throughput

0.232

Low

539582

TOP1
DNA topoisomerase 1

1

0

Small-scale

0.213

Low


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Last updated: 11Aug2025