Protein: ZIC2
Zinc finger protein ZIC 2 (Zinc finger protein of the cerebellum 2)

Gene: ZIC2
Organism: Homo sapiens
Interactions: 37
UniProt ID: O95409

Gene Ontology (top 5):
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 - DNA binding
GO:0003700 - DNA-binding transcription factor activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

336214

GLI3
Transcriptional activator GLI3

1

18

Small-scale

0.724

High

336233

VRK1
Serine/threonine-protein kinase VRK1

1

5

High-throughput

0.691

High

336212

GLI1
Zinc finger protein GLI1

1

18

Small-scale

0.618

High

336213

GLI2
Zinc finger protein GLI2

1

18

Small-scale

0.618

High

336242

FBW1B
F-box/WD repeat-containing protein 11

2

8

High-throughput

0.584

High

336235

EFHD1
EF-hand domain-containing protein D1

2

2

High-throughput

0.558

High

336226

RN180
E3 ubiquitin-protein ligase RNF180

1

0

Small-scale

0.537

High

336218

EFNB1
Ephrin-B1

1

1

High-throughput

0.536

High

336220

EF1A2
Elongation factor 1-alpha 2

1

1

High-throughput

0.536

High

336221

PPID
Peptidyl-prolyl cis-trans isomerase D

1

1

High-throughput

0.536

High

336224

TEAD2
Transcriptional enhancer factor TEF-4

1

2

High-throughput

0.536

High

336227

P3H2
Prolyl 3-hydroxylase 2

1

4

High-throughput

0.536

High

336243

ZHX1
Zinc fingers and homeoboxes protein 1

1

6

High-throughput

0.536

High

336244

HDGR3
Hepatoma-derived growth factor-related protein 3

1

2

High-throughput

0.536

High

336245

ARI1
E3 ubiquitin-protein ligase ARIH1

1

17

High-throughput

0.536

High

336229

ARRD3
Arrestin domain-containing protein 3

1

0

High-throughput

0.513

High

336236

RTF2
Replication termination factor 2

1

0

High-throughput

0.513

High

336230

KCD12
BTB/POZ domain-containing protein KCTD12

1

3

High-throughput

0.489

High

336239

FBLN5
Fibulin-5

1

20

High-throughput

0.489

High

142771

NFIB
Nuclear factor 1 B-type

1

14

High-throughput

0.479

High

174473

TRI66
Tripartite motif-containing protein 66

1

20

High-throughput

0.479

High

336215

TAF1
Transcription initiation factor TFIID subunit 1

1

11

High-throughput

0.479

High

336216

SMCA2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2

1

5

High-throughput

0.479

High

336219

PO5F1
POU domain, class 5, transcription factor 1

1

16

High-throughput

0.479

High

336222

CUL3
Cullin-3

1

20

High-throughput

0.479

High

336228

PHIP
PH-interacting protein

1

2

High-throughput

0.479

High

336232

CIC
Protein capicua homolog

1

16

High-throughput

0.479

High

336237

EGLN3
Prolyl hydroxylase EGLN3

1

2

High-throughput

0.479

High

336238

NANOG
Homeobox protein NANOG

1

11

High-throughput

0.479

High

336217

PRKDC
DNA-dependent protein kinase catalytic subunit

1

5

Small-scale

0.445

High

336225

KLH22
Kelch-like protein 22

1

3

High-throughput

0.445

High

336231

SAHH3
Adenosylhomocysteinase 3

2

0

High-throughput

0.328

High

336241

NAGK
N-acetyl-D-glucosamine kinase

2

0

High-throughput

0.328

High

282147

TECTA
Alpha-tectorin

1

0

High-throughput

0.279

Low

336223

PDE3A
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A

1

0

High-throughput

0.279

Low

336234

CMS1
Protein CMSS1

1

0

High-throughput

0.279

Low

336240

ACHA9
Neuronal acetylcholine receptor subunit alpha-9

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025