Protein: FBX17
F-box only protein 17 (F-box only protein 26)

Gene: FBX17, FBXO17
Organism: Homo sapiens
Interactions: 63
UniProt ID: Q96EF6

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006516 - glycoprotein catabolic process
GO:0019005 - SCF ubiquitin ligase complex
GO:0031146 - SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

992297

SKP1
S-phase kinase-associated protein 1

11

7

Small-scale

0.980

High

1112651

CUL1
Cullin-1

9

8

Small-scale

0.971

High

1388934

FBXW2
F-box/WD repeat-containing protein 2

3

2

High-throughput

0.861

High

1272516

CSN6
COP9 signalosome complex subunit 6

6

4

High-throughput

0.735

High

1370282

CSN5
COP9 signalosome complex subunit 5

6

4

High-throughput

0.735

High

1388927

CSN4
COP9 signalosome complex subunit 4

4

1

High-throughput

0.694

High

1371829

CUL5
Cullin-5

1

8

High-throughput

0.691

High

958691

CSN2
COP9 signalosome complex subunit 2

4

5

High-throughput

0.691

High

251467

NMT2
Glycylpeptide N-tetradecanoyltransferase 2

3

1

High-throughput

0.667

High

532855

CH60
60 kDa heat shock protein, mitochondrial

3

2

High-throughput

0.667

High

719651

NMT1
Glycylpeptide N-tetradecanoyltransferase 1

3

1

High-throughput

0.667

High

1388930

CSN7B
COP9 signalosome complex subunit 7b

3

3

High-throughput

0.667

High

983930

RBX1
E3 ubiquitin-protein ligase RBX1

3

5

Small-scale

0.656

High

1388935

CSN3
COP9 signalosome complex subunit 3

3

6

High-throughput

0.650

High

1388931

SYSM
Serine--tRNA ligase, mitochondrial

2

1

High-throughput

0.611

High

341831

K2C75
Keratin, type II cytoskeletal 75

2

1

High-throughput

0.606

High

1140262

IF4H
Eukaryotic translation initiation factor 4H

2

2

High-throughput

0.606

High

1163749

PTN21
Tyrosine-protein phosphatase non-receptor type 21

2

10

High-throughput

0.606

High

1094395

CSN1
COP9 signalosome complex subunit 1

2

4

High-throughput

0.601

High

715069

OAS2
2'-5'-oligoadenylate synthase 2

2

0

High-throughput

0.580

High

1133143

LASP1
LIM and SH3 domain protein 1

2

0

High-throughput

0.580

High

1198036

KR132
Keratin-associated protein 13-2

2

0

High-throughput

0.580

High

1200140

BOREA
Borealin

2

0

High-throughput

0.580

High

1213806

KPRP
Keratinocyte proline-rich protein

2

0

High-throughput

0.580

High

1294548

DZIP3
E3 ubiquitin-protein ligase DZIP3

2

0

High-throughput

0.580

High

1200321

ANR39
Ankyrin repeat domain-containing protein 39

1

0

High-throughput

0.578

High

1388928

CLPB
Mitochondrial disaggregase

1

5

High-throughput

0.575

High

163511

ZN213
Zinc finger protein 213

2

2

High-throughput

0.553

High

193863

ZSC9
Zinc finger and SCAN domain-containing protein 9

2

2

High-throughput

0.553

High

1225878

SAXO2
Stabilizer of axonemal microtubules 2

2

1

High-throughput

0.553

High

1250281

ATL4
ADAMTS-like protein 4

2

8

High-throughput

0.553

High

1315737

SAXO1
Stabilizer of axonemal microtubules 1

2

1

High-throughput

0.553

High

537693

HSP7C
Heat shock cognate 71 kDa protein

1

2

High-throughput

0.536

High

1388926

CSN8
COP9 signalosome complex subunit 8

1

1

High-throughput

0.536

High

1388933

CSN7A
COP9 signalosome complex subunit 7a

1

3

High-throughput

0.536

High

902875

BLK
Tyrosine-protein kinase Blk

1

0

High-throughput

0.513

High

1360275

CSN9
COP9 signalosome complex subunit 9

1

0

High-throughput

0.513

High

286820

JERKY
Jerky protein homolog

1

0

High-throughput

0.493

High

461801

HS90A
Heat shock protein HSP 90-alpha

1

5

High-throughput

0.479

High

957473

UBC12
NEDD8-conjugating enzyme Ubc12

1

4

High-throughput

0.479

High

992908

RACK1
Small ribosomal subunit protein RACK1

1

2

Small-scale

0.479

High

994334

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

2

Small-scale

0.479

High

1129175

IRF3
Interferon regulatory factor 3

1

1

Small-scale

0.479

High

1388929

TMT1A
Thiol S-methyltransferase TMT1A

1

0

High-throughput

0.458

High

1388932

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.458

High

635361

IMDH1
Inosine-5'-monophosphate dehydrogenase 1

1

1

High-throughput

0.445

High

786208

LONM
Lon protease homolog, mitochondrial

1

3

High-throughput

0.445

High

974955

TYB4
Thymosin beta-4

1

0

High-throughput

0.426

High

1199017

KLH12
Kelch-like protein 12

1

0

High-throughput

0.426

High

223867

NDUA2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2

2

0

High-throughput

0.318

High

278717

NDUS6
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial

2

0

High-throughput

0.318

High

1162477

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

2

0

High-throughput

0.318

High

1029904

RUNX1
Runt-related transcription factor 1

2

0

High-throughput

0.316

High

1185832

ZN829
Zinc finger protein 829

2

0

High-throughput

0.316

High

1258162

UBP54
Ubiquitin carboxyl-terminal hydrolase 54

2

0

High-throughput

0.316

High

1272877

RFIP2
Rab11 family-interacting protein 2

2

0

High-throughput

0.316

High

1332416

CBY2
Protein chibby homolog 2

2

0

High-throughput

0.316

High

458462

ADRB2
Beta-2 adrenergic receptor

1

0

High-throughput

0.282

High

1241137

TATD1
Deoxyribonuclease TATDN1

1

0

High-throughput

0.279

Low

589387

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

768866

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1381932

CK052
Uncharacterized protein C11orf52

1

0

High-throughput

0.249

Low

1157302

PROL4
Proline-rich protein 4

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025