Protein: MANEL
Glycoprotein endo-alpha-1,2-mannosidase-like protein (EC 3.2.1.-)

Gene: MANEL, MANEAL
Organism: Homo sapiens
Interactions: 45
UniProt ID: Q5VSG8

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0004559 - alpha-mannosidase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1084044

SIA4C
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4

3

1

High-throughput

0.667

High

1217312

CGAT2
Chondroitin sulfate N-acetylgalactosaminyltransferase 2

2

1

High-throughput

0.628

High

1197788

S39AC
Zinc transporter ZIP12

3

8

High-throughput

0.604

High

1217310

S22A9
Organic anion transporter 7

3

1

High-throughput

0.604

High

1217326

HS3S2
Heparan sulfate glucosamine 3-O-sulfotransferase 2

2

0

High-throughput

0.602

High

470306

NEP
Neprilysin

2

1

High-throughput

0.574

High

1217323

GGT7
Glutathione hydrolase 7

2

1

High-throughput

0.574

High

647364

IDS
Iduronate 2-sulfatase

2

1

High-throughput

0.558

High

1217316

5HT3C
5-hydroxytryptamine receptor 3C

2

2

High-throughput

0.558

High

1217322

SIAE
Sialate O-acetylesterase

2

1

High-throughput

0.558

High

209379

SIA8C
Alpha-N-acetylneuraminate alpha-2,8-sialyltransferase ST8SIA3

1

1

High-throughput

0.536

High

437703

HEPS
Serine protease hepsin

1

2

High-throughput

0.489

High

731858

CEAM8
Cell adhesion molecule CEACAM8

1

2

High-throughput

0.489

High

851136

ACHA4
Neuronal acetylcholine receptor subunit alpha-4

1

1

High-throughput

0.489

High

1177806

CL12B
C-type lectin domain family 12 member B

1

1

High-throughput

0.489

High

1217309

TM11B
Transmembrane protease serine 11B

1

2

High-throughput

0.489

High

1217317

SAAL1
Protein SAAL1

1

1

High-throughput

0.489

High

1217319

TMPSD
Transmembrane protease serine 13

1

2

High-throughput

0.489

High

1217321

TTYH1
Protein tweety homolog 1

1

1

High-throughput

0.489

High

1217325

PSG8
Pregnancy-specific beta-1-glycoprotein 8

1

2

High-throughput

0.489

High

1217307

ZNT10
Calcium/manganese antiporter SLC30A10

1

4

High-throughput

0.445

High

1217314

ZNT7
Zinc transporter 7

1

4

High-throughput

0.445

High

1217328

ZNT1
Proton-coupled zinc antiporter SLC30A1

1

4

High-throughput

0.445

High

218298

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.437

High

722483

CTR1
High affinity cationic amino acid transporter 1

1

1

High-throughput

0.407

High

912679

CTR2
Cationic amino acid transporter 2

1

1

High-throughput

0.407

High

1139450

S39AE
Metal cation symporter ZIP14

1

8

High-throughput

0.407

High

1217305

S39A4
Zinc transporter ZIP4

1

8

High-throughput

0.407

High

1217308

S39A5
Zinc transporter ZIP5

1

8

High-throughput

0.407

High

1217311

S39AB
Zinc transporter ZIP11

1

8

High-throughput

0.407

High

1217324

S39AA
Zinc transporter ZIP10

1

8

High-throughput

0.407

High

828376

PEX19
Peroxisomal biogenesis factor 19

3

0

High-throughput

0.347

High

931382

AT1B3
Sodium/potassium-transporting ATPase subunit beta-3

3

0

High-throughput

0.347

High

1034747

NAAA
N-acylethanolamine-hydrolyzing acid amidase

3

0

High-throughput

0.347

High

441433

CHLE
Cholinesterase

2

0

High-throughput

0.328

High

519621

LYAG
Lysosomal alpha-glucosidase

2

0

High-throughput

0.328

High

1217306

PXDC2
Plexin domain-containing protein 2

2

0

High-throughput

0.328

High

1217313

I17RC
Interleukin-17 receptor C

2

0

High-throughput

0.328

High

1217318

ASIC4
Acid-sensing ion channel 4

2

0

High-throughput

0.328

High

1217320

ADA33
Disintegrin and metalloproteinase domain-containing protein 33

2

0

High-throughput

0.328

High

518853

CCL3
C-C motif chemokine 3

1

0

High-throughput

0.279

Low

1101352

SG2A2
Mammaglobin-A

1

0

High-throughput

0.279

Low

1217315

CA054
Uncharacterized protein C1orf54

1

0

High-throughput

0.279

Low

1217327

PCDBB
Protocadherin beta-11

1

0

High-throughput

0.279

Low

222286

PSCA
Prostate stem cell antigen

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025