Protein: BEM2
GTPase-activating protein BEM2/IPL2 (Bud emergence protein 2)

Gene: BEM2
Organism: Saccharomyces cerevisiae S288C
Interactions: 106
UniProt ID: P39960

Gene Ontology (top 5):
GO:0000131 - incipient cellular bud site
GO:0003729 - mRNA binding
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005096 - GTPase activator activity
GO:0005628 - prospore membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

694205

BUD14
Bud site selection protein 14

5

1

Small-scale

0.923

High

618348

CDC42
Cell division control protein 42

2

20

Small-scale

0.767

High

792402

BOI1
BEM1-interacting protein 1

1

1

High-throughput

0.698

High

808620

SAK1
SNF1-activating kinase 1

1

1

High-throughput

0.691

High

815858

DUF1
DUB-associated factor 1

1

6

High-throughput

0.691

High

815812

RIO2
Serine/threonine-protein kinase RIO2

3

4

High-throughput

0.671

High

739967

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

1

9

Small-scale

0.647

High

815816

PRK1
Actin-regulating kinase PRK1

1

6

Small-scale

0.647

High

392778

HSP82
ATP-dependent molecular chaperone HSP82

3

12

High-throughput

0.633

High

524037

HSP71
Heat shock protein SSA1

3

7

High-throughput

0.633

High

633471

PP11
Serine/threonine-protein phosphatase PP1-1

2

5

High-throughput

0.621

High

448589

RHO2
GTP-binding protein RHO2

1

20

Small-scale

0.621

High

815836

RHO4
GTP-binding protein RHO4

1

20

Small-scale

0.621

High

622958

CSK22
Casein kinase II subunit alpha'

1

17

High-throughput

0.618

High

793925

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

1

15

High-throughput

0.618

High

810645

SSN3
Meiotic mRNA stability protein kinase SSN3

1

7

High-throughput

0.618

High

815852

RTK1
Probable serine/threonine-protein kinase RTK1

1

6

High-throughput

0.618

High

815819

SA185
SIT4-associating protein SAP185

2

0

High-throughput

0.602

High

815857

ARP7
Actin-related protein 7

1

20

High-throughput

0.595

High

631930

SRP54
Signal recognition particle subunit SRP54

2

0

High-throughput

0.595

High

754475

RT05
Small ribosomal subunit protein uS5m

2

0

High-throughput

0.595

High

579442

HSC82
ATP-dependent molecular chaperone HSC82

2

12

High-throughput

0.571

High

792609

RM16
Large ribosomal subunit protein uL16m

2

0

High-throughput

0.563

High

526765

HSP72
Heat shock protein SSA2

2

7

High-throughput

0.552

High

544972

SSB1
Ribosome-associated molecular chaperone SSB1

2

8

High-throughput

0.552

High

815811

SSB2
Ribosome-associated molecular chaperone SSB2

2

8

High-throughput

0.552

High

815820

NOP2
25S rRNA

2

2

High-throughput

0.537

High

427293

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.536

High

721962

XPO1
Exportin-1

1

17

High-throughput

0.536

High

804183

SSZ1
Ribosome-associated complex subunit SSZ1

1

4

High-throughput

0.536

High

806027

KEL1
Kelch repeat-containing protein 1

1

9

High-throughput

0.536

High

815815

SDP1
Dual-specificity protein phosphatase SDP1

1

1

High-throughput

0.536

High

815822

CSK2B
Casein kinase II subunit beta

1

3

High-throughput

0.536

High

815828

TWF1
Twinfilin-1

1

4

High-throughput

0.536

High

815831

BRE5
UBP3-associated protein BRE5

1

3

High-throughput

0.536

High

815840

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

2

High-throughput

0.536

High

654720

SPA2
Protein SPA2

1

1

High-throughput

0.515

High

744800

ALK2
Serine/threonine-protein kinase Haspin homolog ALK2

1

0

High-throughput

0.513

High

801050

FKS1
1,3-beta-glucan synthase component FKS1

1

0

High-throughput

0.513

High

815854

RAD59
DNA repair protein RAD59

1

0

High-throughput

0.513

High

815838

REG1
Resistance to glucose repression protein 1

1

0

High-throughput

0.493

High

815843

GCN5
Histone acetyltransferase GCN5

1

9

High-throughput

0.489

High

438703

SC160
Protein SCP160

1

9

High-throughput

0.479

High

510522

HSP77
Import motor subunit, mitochondrial

1

8

High-throughput

0.479

High

679716

CDC48
Cell division control protein 48

1

3

High-throughput

0.479

High

721619

RENT1
ATP-dependent helicase NAM7

1

1

Small-scale

0.479

High

727049

HS104
Heat shock protein 104

1

1

High-throughput

0.479

High

743215

PP12
Serine/threonine-protein phosphatase PP1-2

1

3

High-throughput

0.479

High

815814

TM108
Protein TMA108

1

2

High-throughput

0.479

High

815824

MTNB
Methylthioribulose-1-phosphate dehydratase

1

1

High-throughput

0.479

High

815827

CDH1
APC/C activator protein CDH1

1

9

Small-scale

0.479

High

815833

NOP15
Ribosome biogenesis protein 15

1

5

High-throughput

0.479

High

815837

NUM1
Nuclear migration protein NUM1

1

15

High-throughput

0.479

High

815844

YD239
Uncharacterized protein YDR239C

1

1

High-throughput

0.479

High

815845

GIS1
Transcriptional activator/repressor GIS1

1

9

High-throughput

0.479

High

815849

VIP1
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase

1

1

High-throughput

0.479

High

815853

RIO1
Serine/threonine-protein kinase RIO1

1

4

High-throughput

0.479

High

438439

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

1

High-throughput

0.470

High

689043

RL16A
Large ribosomal subunit protein uL13A

1

0

High-throughput

0.458

High

747872

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

796485

YBS1
Uncharacterized protein YBR071W

1

0

High-throughput

0.458

High

815830

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

815846

FIN1
Filament protein FIN1

1

0

Small-scale

0.458

High

815850

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

815851

TMA46
Translation machinery-associated protein 46

1

0

High-throughput

0.458

High

394589

EF1A
Elongation factor 1-alpha

1

6

High-throughput

0.445

High

518030

SSBP1
Single-stranded nucleic acid-binding protein

1

3

High-throughput

0.445

High

575950

CYPH
Peptidyl-prolyl cis-trans isomerase

1

5

High-throughput

0.445

High

592276

VATB
V-type proton ATPase subunit B

1

2

High-throughput

0.445

High

676022

MAS5
Mitochondrial protein import protein MAS5

1

2

High-throughput

0.445

High

741634

HSP7F
Heat shock protein homolog SSE1

1

10

High-throughput

0.445

High

806963

2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

1

1

High-throughput

0.445

High

815825

PFD3
Prefoldin subunit 3

1

1

High-throughput

0.445

High

815832

PFD4
Prefoldin subunit 4

1

2

High-throughput

0.445

High

815834

APJ1
J domain-containing protein APJ1

1

2

High-throughput

0.445

High

815856

HSP42
Heat shock protein 42

1

1

High-throughput

0.445

High

382115

H4
Histone H4

1

4

High-throughput

0.437

High

444773

SIR2
NAD-dependent histone deacetylase SIR2

1

2

High-throughput

0.437

High

707174

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

815817

ULP2
Ubiquitin-like-specific protease 2

1

2

High-throughput

0.437

High

815835

H3
Histone H3

1

9

High-throughput

0.437

High

815847

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.437

High

815855

SMT3
Ubiquitin-like protein SMT3

1

2

High-throughput

0.437

High

737407

FKBP2
Peptidyl-prolyl cis-trans isomerase FPR2

1

0

High-throughput

0.426

High

419743

H2A2
Histone H2A.2

1

4

High-throughput

0.407

High

815841

ADA2
SAGA complex subunit ADA2

1

4

High-throughput

0.407

High

815848

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

6

High-throughput

0.407

High

815813

PP4R3
Serine/threonine-protein phosphatase 4 regulatory subunit 3

2

0

High-throughput

0.324

High

815839

MCE1
mRNA-capping enzyme subunit alpha

2

0

High-throughput

0.307

High

815842

LGE1
Transcriptional regulatory protein LGE1

2

0

High-throughput

0.298

High

801746

SRP72
Signal recognition particle subunit SRP72

1

0

High-throughput

0.279

Low

815821

KRI1
Protein KRI1

1

0

High-throughput

0.279

Low

815829

SLX9
Ribosome biogenesis protein SLX9

1

0

High-throughput

0.279

Low

739641

SPT16
FACT complex subunit SPT16

1

0

High-throughput

0.269

Low

594381

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.249

Low

693493

CBPS
Carboxypeptidase S

1

0

High-throughput

0.249

Low

763896

SPT10
Protein SPT10

1

0

High-throughput

0.249

Low

764082

SPT21
Protein SPT21

1

0

High-throughput

0.249

Low

807807

SSN2
Mediator of RNA polymerase II transcription subunit 13

1

0

Small-scale

0.249

Low

812322

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

815818

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

815823

NET1
Nucleolar protein NET1

1

0

High-throughput

0.249

Low

815826

UBC9
SUMO-conjugating enzyme UBC9

1

0

High-throughput

0.249

Low

455080

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.232

Low

803866

CIC1
Proteasome-interacting protein CIC1

1

0

High-throughput

0.232

Low

807223

SPT8
SAGA complex subunit SPT8

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025