Protein: NUP53
Nucleoporin NUP53 (Nuclear pore protein NUP53)

Gene: NUP53
Organism: Saccharomyces cerevisiae S288C
Interactions: 78
UniProt ID: Q03790

Gene Ontology (top 5):
GO:0003697 - single-stranded DNA binding
GO:0005543 - phospholipid binding
GO:0005635 - nuclear envelope
GO:0005643 - nuclear pore
GO:0006606 - protein import into nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1044090

NUP53
Nucleoporin NUP53

6

2

Small-scale

0.935

High

1044093

NUP59
Nucleoporin ASM4

4

2

Small-scale

0.885

High

795191

NU170
Nucleoporin NUP170

11

3

Small-scale

0.755

High

734724

IMB3
Importin subunit beta-3

9

4

Small-scale

0.754

High

756658

NIC96
Nucleoporin NIC96

9

1

Small-scale

0.749

High

738558

NDC1
Nucleoporin NDC1

6

1

Small-scale

0.729

High

817818

NU157
Nucleoporin NUP157

6

3

Small-scale

0.726

High

864647

NU192
Nucleoporin NUP192

5

1

Small-scale

0.711

High

914993

NUP84
Nucleoporin NUP84

5

1

Small-scale

0.702

High

1044095

IMB1
Importin subunit beta-1

3

4

Small-scale

0.651

High

782552

NU133
Nucleoporin NUP133

3

1

High-throughput

0.640

High

823499

NUP82
Nucleoporin NUP82

3

1

Small-scale

0.636

High

886204

NU145
Nucleoporin NUP145

3

12

High-throughput

0.636

High

813431

PO152
Nucleoporin POM152

2

1

High-throughput

0.600

High

577343

NSP1
Nucleoporin NSP1

2

9

High-throughput

0.584

High

825174

NU159
Nucleoporin NUP159

2

7

High-throughput

0.584

High

912749

NU188
Nucleoporin NUP188

2

1

High-throughput

0.584

High

1036918

MLP1
Protein MLP1

2

3

High-throughput

0.584

High

858323

NUP85
Nucleoporin NUP85

2

1

Small-scale

0.576

High

1037979

NU116
Nucleoporin NUP116/NSP116

2

14

Small-scale

0.571

High

829791

MAD1
Spindle assembly checkpoint component MAD1

2

0

Small-scale

0.569

High

1038094

ULP1
Ubiquitin-like-specific protease 1

1

0

Small-scale

0.537

High

738916

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

2

1

Small-scale

0.533

High

808547

TEM1
Protein TEM1

1

0

High-throughput

0.513

High

709457

HRR25
Casein kinase I homolog HRR25

1

1

Small-scale

0.512

High

527573

HSP72
Heat shock protein SSA2

2

1

High-throughput

0.504

High

815877

KC13
Casein kinase I homolog 3

1

4

Small-scale

0.501

High

441242

KAPA
cAMP-dependent protein kinase type 1

1

0

Small-scale

0.480

High

599400

FUS3
Mitogen-activated protein kinase FUS3

1

0

Small-scale

0.480

High

634274

NUP1
Nucleoporin NUP1

1

5

High-throughput

0.479

High

803813

BRL1
Nucleus export protein BRL1

1

1

Small-scale

0.479

High

824782

MLP2
Protein MLP2

1

3

High-throughput

0.479

High

826793

DSN1
Kinetochore-associated protein DSN1

1

1

High-throughput

0.479

High

877978

NUP57
Nucleoporin NUP57

1

8

High-throughput

0.479

High

886178

NUP42
Nucleoporin NUP42

1

9

High-throughput

0.479

High

1044102

POM34
Nucleoporin POM34

1

1

High-throughput

0.479

High

1038152

CENPP
Inner kinetochore subunit CTF19

1

0

High-throughput

0.460

High

776541

NU120
Nucleoporin NUP120

1

0

High-throughput

0.458

High

916423

SEH1
Nucleoporin SEH1

1

0

High-throughput

0.458

High

1044091

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.458

High

1044104

MEX67
mRNA export factor MEX67

1

0

High-throughput

0.458

High

656607

KC11
Casein kinase I homolog 1

1

4

Small-scale

0.457

High

656861

KC12
Casein kinase I homolog 2

1

4

Small-scale

0.457

High

865539

PTK2
Serine/threonine-protein kinase PTK2/STK2

1

1

Small-scale

0.457

High

525020

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

858354

SAC3
Nuclear mRNA export protein SAC3

1

1

High-throughput

0.437

High

892812

CTF18
Chromosome transmission fidelity protein 18

1

1

High-throughput

0.437

High

893294

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

1

High-throughput

0.437

High

797127

CENPL
Inner kinetochore subunit IML3

1

0

High-throughput

0.426

High

1044092

SPC24
Kinetochore protein SPC24

1

0

High-throughput

0.426

High

546119

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.407

High

742308

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.407

High

819677

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.407

High

795518

ATG8
Autophagy-related protein 8

2

0

Small-scale

0.305

High

864427

IKS1
Probable serine/threonine-protein kinase IKS1

1

0

High-throughput

0.282

High

1044096

PEX30
Peroxisomal membrane protein PEX30

1

0

High-throughput

0.282

High

1044103

PGA3
Plasma membrane-associated coenzyme Q6 reductase PGA3

1

0

High-throughput

0.282

High

550077

RAP1
DNA-binding protein RAP1

1

0

Small-scale

0.279

Low

743128

STH1
Nuclear protein STH1/NPS1

1

0

Small-scale

0.279

Low

704650

SBA1
Co-chaperone protein SBA1

1

0

Small-scale

0.275

Low

602622

PHO85
Cyclin-dependent protein kinase PHO85

1

0

High-throughput

0.261

Low

649666

KCC2
Calcium/calmodulin-dependent protein kinase II

1

0

High-throughput

0.261

Low

808420

HAL5
Serine/threonine-protein kinase HAL5

1

0

Small-scale

0.261

Low

822016

PSA4
Proteasome subunit alpha type-4

1

0

Small-scale

0.261

Low

849946

BLM10
Proteasome activator BLM10

1

0

Small-scale

0.261

Low

1042991

STE20
Serine/threonine-protein kinase STE20

1

0

Small-scale

0.261

Low

1044100

GIN4
Serine/threonine-protein kinase GIN4

1

0

High-throughput

0.261

Low

697393

MIG1
Regulatory protein MIG1

1

0

Small-scale

0.249

Low

708063

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

1043562

ESC1
Silent chromatin protein ESC1

1

0

Small-scale

0.249

Low

1044099

LSP1
Sphingolipid long chain base-responsive protein LSP1

1

0

High-throughput

0.249

Low

1044094

ERP1
Protein ERP1

1

0

High-throughput

0.238

Low

1044097

PMT7
Probable dolichyl-phosphate-mannose--protein mannosyltransferase 7

1

0

High-throughput

0.238

Low

1044098

INP54
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase INP54

1

0

High-throughput

0.238

Low

368049

ENO2
Enolase 2

1

0

High-throughput

0.232

Low

592475

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.232

Low

1044101

HMS1
Probable transcription factor HMS1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025