Protein: SECU
Securin

Gene: SECU, PDS1
Organism: Saccharomyces cerevisiae S288C
Interactions: 54
UniProt ID: P40316

Gene Ontology (top 5):
GO:0000070 - mitotic sister chromatid segregation
GO:0000725 - recombinational repair
GO:0001100 - negative regulation of exit from mitosis
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

822237

ESP1
Separin

12

0

Small-scale

0.930

High

684623

CDC20
APC/C activator protein CDC20

13

1

Small-scale

0.761

High

822230

CDH1
APC/C activator protein CDH1

12

1

Small-scale

0.757

High

364569

CDK1
Cyclin-dependent kinase 1

5

1

Small-scale

0.728

High

794269

CHK1
Serine/threonine-protein kinase CHK1

3

0

Small-scale

0.652

High

735507

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

1

High-throughput

0.536

High

739841

MSS1
tRNA modification GTPase MSS1, mitochondrial

1

0

High-throughput

0.513

High

743032

SWI3
SWI/SNF complex subunit SWI3

1

0

High-throughput

0.513

High

822236

IMA1
Importin subunit alpha

1

0

High-throughput

0.513

High

602491

PHO85
Cyclin-dependent protein kinase PHO85

1

1

High-throughput

0.501

High

795643

UBP13
Ubiquitin carboxyl-terminal hydrolase 13

1

1

Small-scale

0.501

High

796396

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

1

Small-scale

0.501

High

822225

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

1

Small-scale

0.501

High

822231

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

2

Small-scale

0.501

High

822234

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

1

2

Small-scale

0.501

High

822235

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

3

Small-scale

0.501

High

751414

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

0

High-throughput

0.493

High

441151

KAPA
cAMP-dependent protein kinase type 1

1

0

High-throughput

0.480

High

448737

SNF1
Carbon catabolite-derepressing protein kinase

1

0

High-throughput

0.480

High

509582

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

0

Small-scale

0.480

High

656490

KC11
Casein kinase I homolog 1

1

0

High-throughput

0.480

High

660797

PP2A1
Serine/threonine-protein phosphatase PP2A-1 catalytic subunit

1

0

Small-scale

0.480

High

668271

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

0

Small-scale

0.480

High

692368

KCC1
Calcium/calmodulin-dependent protein kinase I

1

0

High-throughput

0.480

High

812857

UBP12
Ubiquitin carboxyl-terminal hydrolase 12

1

0

Small-scale

0.480

High

822218

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

0

Small-scale

0.480

High

822220

OTU1
Ubiquitin thioesterase OTU1

1

0

Small-scale

0.480

High

822221

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

0

Small-scale

0.480

High

822223

PTK2
Serine/threonine-protein kinase PTK2/STK2

1

0

High-throughput

0.480

High

822226

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

0

Small-scale

0.480

High

822229

ATG1
Serine/threonine-protein kinase ATG1

1

0

High-throughput

0.480

High

822233

2ABA
Protein phosphatase PP2A regulatory subunit B

1

0

Small-scale

0.480

High

746282

UGPA1
UTP--glucose-1-phosphate uridylyltransferase

1

0

High-throughput

0.479

High

822232

ACT
Actin

1

0

High-throughput

0.479

High

646425

RAD53
Serine/threonine-protein kinase RAD53

1

0

High-throughput

0.458

High

524121

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

526835

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

545080

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

741684

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

818899

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

392820

HSP82
ATP-dependent molecular chaperone HSP82

1

0

High-throughput

0.426

High

510541

HSP77
Import motor subunit, mitochondrial

1

0

High-throughput

0.426

High

727073

HS104
Heat shock protein 104

1

0

High-throughput

0.426

High

739383

ZUO1
Zuotin

1

0

High-throughput

0.426

High

804200

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.426

High

822217

SECU
Securin

1

0

Small-scale

0.391

High

822227

NUP84
Nucleoporin NUP84

1

0

High-throughput

0.282

High

822224

AZR1
Azole resistance protein 1

1

0

High-throughput

0.279

Low

822222

UBP6
Ubiquitin carboxyl-terminal hydrolase 6

1

0

Small-scale

0.261

Low

405098

LEU3
3-isopropylmalate dehydrogenase

1

0

High-throughput

0.261

Low

555089

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.261

Low

822219

EPS1
ER-retained PMA1-suppressing protein 1

1

0

Small-scale

0.249

Low

822228

ERG25
C-4 methylsterol oxidase ERG25

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025