Protein: NNF1
Kinetochore-associated protein NNF1

Gene: NNF1
Organism: Saccharomyces cerevisiae S288C
Interactions: 107
UniProt ID: P47149

Gene Ontology (top 5):
GO:0000444 - MIS12/MIND type complex
GO:0000776 - kinetochore
GO:0000922 - spindle pole
GO:0000940 - outer kinetochore
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

826634

DSN1
Kinetochore-associated protein DSN1

21

0

Small-scale

0.936

High

814079

MTW1
Kinetochore-associated protein MTW1

13

0

Small-scale

0.930

High

866078

NSL1
Kinetochore-associated protein NSL1

9

0

Small-scale

0.916

High

866043

NNF1
Kinetochore-associated protein NNF1

2

0

Small-scale

0.736

High

797890

CENPU
Inner kinetochore subunit AME1

10

0

Small-scale

0.722

High

763746

CENPC
Inner kinetochore subunit MIF2

4

0

Small-scale

0.662

High

602053

KAR3
Kinesin-like protein KAR3

4

0

Small-scale

0.658

High

755263

NUF2
Kinetochore protein NUF2

3

0

Small-scale

0.630

High

866047

KNL1
Outer kinetochore KNL1 complex subunit SPC105

3

0

High-throughput

0.627

High

824847

NDC80
Kinetochore protein NDC80

3

0

High-throughput

0.621

High

866084

SMC4
Structural maintenance of chromosomes protein 4

2

1

High-throughput

0.595

High

817004

SPC25
Kinetochore protein SPC25

2

0

High-throughput

0.576

High

555265

RAD50
DNA repair protein RAD50

2

0

High-throughput

0.570

High

815649

LIS1
Nuclear distribution protein PAC1

2

0

High-throughput

0.570

High

866046

PFD6
Prefoldin subunit 6

2

0

High-throughput

0.570

High

866056

CIK1
Spindle pole body-associated protein CIK1

2

0

High-throughput

0.570

High

866069

HDA2
HDA1 complex subunit 2

2

0

High-throughput

0.570

High

866051

CENPQ
Inner kinetochore subunit OKP1

2

0

Small-scale

0.569

High

866070

CENPO
Inner kinetochore subunit MCM21

2

0

Small-scale

0.569

High

866059

CENPP
Inner kinetochore subunit CTF19

2

0

Small-scale

0.569

High

866074

SGO1
Shugoshin

2

0

High-throughput

0.561

High

779282

CENPA
Histone H3-like centromeric protein CSE4

2

0

Small-scale

0.559

High

781569

NTR2
Pre-mRNA-splicing factor NTR2

2

0

High-throughput

0.559

High

866083

CENPH
Inner kinetochore subunit MCM16

2

0

Small-scale

0.547

High

866086

CENPI
Inner kinetochore subunit CTF3

2

0

Small-scale

0.547

High

448317

PDE2
3',5'-cyclic-nucleotide phosphodiesterase 2

1

0

High-throughput

0.518

High

524445

HSP71
Heat shock protein SSA1

1

0

High-throughput

0.513

High

722069

XPO1
Exportin-1

1

0

High-throughput

0.513

High

866054

MPS1
Serine/threonine-protein kinase MPS1

1

0

High-throughput

0.513

High

747741

SMC1
Structural maintenance of chromosomes protein 1

1

1

High-throughput

0.508

High

827003

MET28
Transcriptional activator of sulfur metabolism MET28

1

0

High-throughput

0.486

High

866073

SMC5
Structural maintenance of chromosomes protein 5

1

2

High-throughput

0.481

High

673713

KCC4
Probable serine/threonine-protein kinase KCC4

1

0

High-throughput

0.480

High

865496

PTK2
Serine/threonine-protein kinase PTK2/STK2

1

0

High-throughput

0.480

High

866082

PKH2
Serine/threonine-protein kinase PKH2

1

0

High-throughput

0.480

High

626517

AP1
AP-1-like transcription factor YAP1

1

0

High-throughput

0.460

High

646059

KIN3
Serine/threonine-protein kinase KIN3

1

0

High-throughput

0.460

High

665835

KPC1
Protein kinase C-like 1

1

0

High-throughput

0.460

High

735391

MCM10
Minichromosome maintenance protein 10

1

0

High-throughput

0.460

High

736022

SP110
Spindle pole body component 110

1

0

High-throughput

0.460

High

739081

PAN1
Actin cytoskeleton-regulatory complex protein PAN1

1

0

High-throughput

0.460

High

750720

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.460

High

777079

BDF1
Bromodomain-containing factor 1

1

0

High-throughput

0.460

High

794192

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

1

0

High-throughput

0.460

High

823217

MED3
Mediator of RNA polymerase II transcription subunit 3

1

0

High-throughput

0.460

High

863922

SET2
Histone-lysine N-methyltransferase, H3 lysine-36 specific

1

0

High-throughput

0.460

High

866053

CNM67
Chaotic nuclear migration protein 67

1

0

High-throughput

0.460

High

866057

PRS8
26S proteasome regulatory subunit 8 homolog

1

0

High-throughput

0.460

High

866058

ULP1
Ubiquitin-like-specific protease 1

1

0

High-throughput

0.460

High

866060

SPP1
COMPASS component SPP1

1

0

High-throughput

0.460

High

866061

NHP10
Non-histone protein 10

1

0

High-throughput

0.460

High

866068

ARR1
Arsenical-resistance protein ARR1

1

0

High-throughput

0.460

High

866071

MFG1
Morphogenetic regulator of filamentous growth protein 1

1

0

High-throughput

0.460

High

866076

YP216
Putative ISWI chromatin-remodeling complex subunit YPL216W

1

0

High-throughput

0.460

High

866077

SRL2
Protein SRL2

1

0

High-throughput

0.460

High

866085

MPC70
Sporulation-specific protein 21

1

0

High-throughput

0.460

High

548220

BIK1
Nuclear fusion protein BIK1

1

0

Small-scale

0.458

High

807019

CENPN
Inner kinetochore subunit CHL4

1

0

Small-scale

0.458

High

829973

CBF3B
Centromere DNA-binding protein complex CBF3 subunit B

1

0

Small-scale

0.458

High

850684

CENPT
Inner kinetochore subunit CNN1

1

0

Small-scale

0.458

High

858379

STU2
Protein STU2

1

0

Small-scale

0.458

High

865895

BIR1
Chromosomal passenger complex protein BIR1

1

0

Small-scale

0.458

High

866064

ZWINT
Outer kinetochore KNL1 complex subunit KRE28

1

0

High-throughput

0.458

High

866065

SPC24
Kinetochore protein SPC24

1

0

High-throughput

0.458

High

866075

SLK19
Kinetochore protein SLK19

1

0

Small-scale

0.458

High

866079

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

866080

PSH1
RING finger protein PSH1

1

0

Small-scale

0.458

High

545440

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

819172

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

623889

MYO2
Myosin-2

2

0

High-throughput

0.310

High

866049

MPS2
Monopolar spindle protein 2

2

0

High-throughput

0.310

High

866055

NUM1
Nuclear migration protein NUM1

2

0

High-throughput

0.310

High

866072

YL031
Putative uncharacterized protein YLR031W

2

0

High-throughput

0.304

High

678885

CSM1
Monopolin complex subunit CSM1

1

0

Small-scale

0.279

Low

724300

ZIP1
Synaptonemal complex protein ZIP1

1

0

High-throughput

0.251

Low

735645

SMY1
Kinesin-related protein SMY1

1

0

High-throughput

0.251

Low

737006

CDC3
Cell division control protein 3

1

0

High-throughput

0.251

Low

743872

YEF3
Uncharacterized protein YEL043W

1

0

High-throughput

0.251

Low

755062

TIP20
Protein transport protein TIP20

1

0

High-throughput

0.251

Low

758115

CASP
Protein CASP

1

0

High-throughput

0.251

Low

779775

DYHC
Dynein heavy chain, cytoplasmic

1

0

High-throughput

0.251

Low

790453

PAM1
Protein PAM1

1

0

High-throughput

0.251

Low

795691

ECM13
Protein ECM13

1

0

High-throughput

0.251

Low

797292

YSW1
Spore-specific protein YSW1

1

0

High-throughput

0.251

Low

802519

SYSM
Serine--tRNA ligase, mitochondrial

1

0

High-throughput

0.251

Low

803299

ETP1
RING finger protein ETP1

1

0

High-throughput

0.251

Low

811269

RGA1
Rho-type GTPase-activating protein 1

1

0

High-throughput

0.251

Low

815033

SNF7
Vacuolar-sorting protein SNF7

1

0

High-throughput

0.251

Low

817740

TSC11
Target of rapamycin complex 2 subunit TSC11

1

0

High-throughput

0.251

Low

836577

SPR3
Sporulation-regulated protein 3

1

0

High-throughput

0.251

Low

864568

YJE9
Uncharacterized protein YJL049W

1

0

High-throughput

0.251

Low

864722

BBC1
Myosin tail region-interacting protein MTI1

1

0

High-throughput

0.251

Low

866044

NUP57
Nucleoporin NUP57

1

0

High-throughput

0.251

Low

866045

KEL2
Kelch repeat-containing protein 2

1

0

High-throughput

0.251

Low

866048

KXD1
Biogenesis of lysosome-related organelles complex 1 subunit KXD1

1

0

High-throughput

0.251

Low

866050

YG3A
Uncharacterized protein YGR130C

1

0

High-throughput

0.251

Low

866052

AP18B
Clathrin coat assembly protein AP180B

1

0

High-throughput

0.251

Low

866062

BUL2
Ubiquitin ligase-binding protein BUL2

1

0

High-throughput

0.251

Low

866063

SHE9
Sensitive to high expression protein 9, mitochondrial

1

0

High-throughput

0.251

Low

866066

ATG38
PtdIns3K complex I subunit atg38

1

0

High-throughput

0.251

Low

866067

HOB2
Protein YPR117W

1

0

High-throughput

0.251

Low

866081

RUD3
GRIP domain-containing protein RUD3

1

0

High-throughput

0.251

Low

866087

HPH1
Protein HPH1

1

0

High-throughput

0.251

Low

805410

BZZ1
Protein BZZ1

1

0

High-throughput

0.249

Low

752466

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low

810723

TCPB
T-complex protein 1 subunit beta

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025