Protein: SYSM
Serine--tRNA ligase, mitochondrial (EC 6.1.1.11) (Digs into agar protein 4) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser) synthetase)

Gene: SYSM, DIA4
Organism: Saccharomyces cerevisiae S288C
Interactions: 44
UniProt ID: P38705

Gene Ontology (top 5):
GO:0000049 - tRNA binding
GO:0004828 - serine-tRNA ligase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

734852

PP4C
Serine/threonine-protein phosphatase 4 catalytic subunit

1

2

High-throughput

0.536

High

802520

PUS4
tRNA pseudouridine synthase 4

1

1

High-throughput

0.515

High

802515

YRB2
Ran-specific GTPase-activating protein 2

1

0

High-throughput

0.513

High

802524

BUD32
EKC/KEOPS complex subunit BUD32

1

0

High-throughput

0.513

High

646032

KIN3
Serine/threonine-protein kinase KIN3

1

1

High-throughput

0.481

High

753071

NIP80
Protein NIP100

1

1

High-throughput

0.481

High

790441

PAM1
Protein PAM1

1

1

High-throughput

0.481

High

802508

LAM4
Membrane-anchored lipid-binding protein LAM4

1

1

High-throughput

0.481

High

802510

LIS1
Nuclear distribution protein PAC1

1

4

High-throughput

0.481

High

802513

TBP6
Probable 26S proteasome subunit YTA6

1

10

High-throughput

0.481

High

802516

GCN20
Protein GCN20

1

6

High-throughput

0.481

High

802526

PRS8
26S proteasome regulatory subunit 8 homolog

1

4

High-throughput

0.481

High

802529

SVL3
Styryl dye vacuolar localization protein 3

1

1

High-throughput

0.481

High

802532

VPS20
Vacuolar protein sorting-associated protein 20

1

3

High-throughput

0.481

High

802531

PDR15
ATP-dependent permease PDR15

1

2

High-throughput

0.479

High

725962

SWC3
SWR1-complex protein 3

1

0

High-throughput

0.460

High

781554

NTR2
Pre-mRNA-splicing factor NTR2

1

0

High-throughput

0.460

High

802509

RGA1
Rho-type GTPase-activating protein 1

1

0

High-throughput

0.460

High

802521

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.460

High

802530

SNX41
Sorting nexin-41

1

0

High-throughput

0.460

High

802534

HDA2
HDA1 complex subunit 2

1

0

High-throughput

0.460

High

802536

SLK19
Kinetochore protein SLK19

1

0

High-throughput

0.460

High

802537

GYP5
GTPase-activating protein GYP5

1

0

High-throughput

0.460

High

792788

ANM1
Protein arginine N-methyltransferase 1

1

3

Small-scale

0.457

High

802527

UBC7
Ubiquitin-conjugating enzyme E2 7

1

5

High-throughput

0.457

High

523824

HSP71
Heat shock protein SSA1

1

3

High-throughput

0.445

High

526595

HSP72
Heat shock protein SSA2

1

3

High-throughput

0.445

High

544734

SSB1
Ribosome-associated molecular chaperone SSB1

1

4

High-throughput

0.445

High

726993

HS104
Heat shock protein 104

1

3

High-throughput

0.445

High

802511

HSP7E
Heat shock protein SSC3, mitochondrial

1

2

High-throughput

0.445

High

758087

CASP
Protein CASP

1

1

High-throughput

0.439

High

802514

UTP18
U3 small nucleolar RNA-associated protein 18

2

0

High-throughput

0.307

High

755235

NUF2
Kinetochore protein NUF2

1

0

High-throughput

0.251

Low

790314

VPP2
V-type proton ATPase subunit a, Golgi isoform

1

0

High-throughput

0.251

Low

802512

SPC25
Kinetochore protein SPC25

1

0

High-throughput

0.251

Low

802517

SUM1
Suppressor of mar1-1 protein

1

0

High-throughput

0.251

Low

802518

STB2
Protein STB2

1

0

High-throughput

0.251

Low

802519

NNF1
Kinetochore-associated protein NNF1

1

0

High-throughput

0.251

Low

802522

NNF2
Protein NNF2

1

0

High-throughput

0.251

Low

802523

CENPQ
Inner kinetochore subunit OKP1

1

0

High-throughput

0.251

Low

802525

SAE3
Pachytene arrest protein SAE3

1

0

High-throughput

0.251

Low

802528

ULP1
Ubiquitin-like-specific protease 1

1

0

High-throughput

0.251

Low

802533

SPC24
Kinetochore protein SPC24

1

0

High-throughput

0.251

Low

802535

YAP7
AP-1-like transcription factor YAP7

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025