Protein: SLT11
Pre-mRNA-splicing factor SLT11 (Extracellular mutant protein 2) (Synthetic lethality with U2 protein 11)

Gene: SLT11, ECM2
Organism: Saccharomyces cerevisiae S288C
Interactions: 78
UniProt ID: P38241

Gene Ontology (top 5):
GO:0000398 - mRNA splicing, via spliceosome
GO:0000974 - Prp19 complex
GO:0005634 - nucleus
GO:0017070 - U6 snRNA binding
GO:0036002 - pre-mRNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

796460

CEF1
Pre-mRNA-splicing factor CEF1

6

4

Small-scale

0.947

High

796472

CWC2
Pre-mRNA-splicing factor CWC2

3

2

High-throughput

0.861

High

739133

PRP19
Pre-mRNA-processing factor 19

5

3

Small-scale

0.714

High

796475

PRP46
Pre-mRNA-splicing factor PRP46

4

2

High-throughput

0.697

High

796474

CLF1
Pre-mRNA-splicing factor CLF1

4

6

Small-scale

0.691

High

796453

RUXF
Small nuclear ribonucleoprotein F

3

1

High-throughput

0.643

High

796471

RU2A
U2 small nuclear ribonucleoprotein A'

3

2

Small-scale

0.640

High

672052

BUD31
Pre-mRNA-splicing factor BUD31

1

2

High-throughput

0.618

High

700097

PRP45
Pre-mRNA-processing protein 45

1

2

High-throughput

0.618

High

744106

BRR2
Pre-mRNA-splicing helicase BRR2

2

6

High-throughput

0.611

High

751729

PRP8
Pre-mRNA-splicing factor 8

2

3

High-throughput

0.611

High

664592

PRP22
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22

2

3

Small-scale

0.595

High

702243

YJU2
Splicing factor YJU2

2

1

Small-scale

0.595

High

392630

HSP82
ATP-dependent molecular chaperone HSP82

2

1

High-throughput

0.588

High

726970

HS104
Heat shock protein 104

2

1

High-throughput

0.588

High

579279

HSC82
ATP-dependent molecular chaperone HSC82

3

1

High-throughput

0.587

High

796465

SN309
Pre-mRNA-splicing factor SNT309

2

0

High-throughput

0.585

High

628204

PRP2
Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2

2

3

High-throughput

0.584

High

796441

RSMB
Small nuclear ribonucleoprotein-associated protein B

2

1

High-throughput

0.584

High

796458

SLU7
Pre-mRNA-splicing factor SLU7

2

1

Small-scale

0.584

High

796470

NCBP2
Nuclear cap-binding protein subunit 2

2

2

High-throughput

0.584

High

796452

CWC25
Pre-mRNA-splicing factor CWC25

2

1

High-throughput

0.571

High

526517

HSP72
Heat shock protein SSA2

2

1

High-throughput

0.552

High

779045

EF1G2
Elongation factor 1-gamma 2

1

1

High-throughput

0.515

High

796467

SP382
Pre-mRNA-splicing factor SPP382

1

0

High-throughput

0.513

High

796438

SLT11
Pre-mRNA-splicing factor SLT11

1

1

Small-scale

0.501

High

555248

RAD50
DNA repair protein RAD50

1

0

High-throughput

0.493

High

670254

NAP1
Nucleosome assembly protein

1

0

High-throughput

0.493

High

590195

PRP16
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

1

3

High-throughput

0.479

High

638058

ISY1
Pre-mRNA-splicing factor ISY1

1

1

High-throughput

0.479

High

739241

PRP21
Pre-mRNA-splicing factor PRP21

1

1

High-throughput

0.479

High

780174

SN114
Pre-mRNA-splicing factor SNU114

1

2

High-throughput

0.479

High

796443

RUXG
Small nuclear ribonucleoprotein G

1

2

High-throughput

0.479

High

796445

IST3
U2 snRNP component IST3

1

2

High-throughput

0.479

High

796446

PRP17
Pre-mRNA-processing factor 17

1

4

High-throughput

0.479

High

796447

SMD3
Small nuclear ribonucleoprotein Sm D3

1

2

High-throughput

0.479

High

796449

SF3B1
U2 snRNP component HSH155

1

1

High-throughput

0.479

High

796451

CWC22
Pre-mRNA-splicing factor CWC22

1

1

High-throughput

0.479

High

796457

CWC27
Peptidyl-prolyl isomerase CWC27

1

1

High-throughput

0.479

High

796462

SYF1
Pre-mRNA-splicing factor SYF1

1

5

High-throughput

0.479

High

796469

PRP11
Pre-mRNA-splicing factor PRP11

1

1

High-throughput

0.479

High

796444

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

1

High-throughput

0.470

High

796463

EIF3G
Eukaryotic translation initiation factor 3 subunit G

1

2

High-throughput

0.470

High

625092

PRP9
Pre-mRNA-splicing factor PRP9

1

0

High-throughput

0.458

High

706913

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

709725

BMH1
Protein BMH1

1

0

High-throughput

0.458

High

757479

NCBP1
Nuclear cap-binding protein complex subunit 1

1

0

High-throughput

0.458

High

781551

NTR2
Pre-mRNA-splicing factor NTR2

1

0

High-throughput

0.458

High

781976

YK21
Uncharacterized protein YKR041W

1

0

High-throughput

0.458

High

796439

NTC20
Pre-mRNA-splicing factor NTC20

1

0

High-throughput

0.458

High

796448

CWC26
Pre-mRNA-splicing factor CWC26

1

0

High-throughput

0.458

High

796450

SYF2
Pre-mRNA-splicing factor SYF2

1

0

High-throughput

0.458

High

796454

SMD1
Small nuclear ribonucleoprotein Sm D1

1

0

High-throughput

0.458

High

796455

SPP2
Pre-mRNA-splicing factor SPP2

1

0

High-throughput

0.458

High

796456

CUS1
Cold sensitive U2 snRNA suppressor 1

1

0

High-throughput

0.458

High

796459

CWC21
Pre-mRNA-splicing factor CWC21

1

0

High-throughput

0.458

High

796461

CWC15
Pre-mRNA-splicing factor CWC15

1

0

High-throughput

0.458

High

796464

RSE1
Pre-mRNA-splicing factor RSE1

1

0

High-throughput

0.458

High

796466

SMD2
Small nuclear ribonucleoprotein Sm D2

1

0

High-throughput

0.458

High

796468

RDS3
Pre-mRNA-splicing factor RDS3

1

0

High-throughput

0.458

High

796476

SNU66
66 kDa U4/U6.U5 small nuclear ribonucleoprotein component

1

0

Small-scale

0.458

High

796477

HAA1
Transcriptional activator HAA1

1

0

High-throughput

0.458

High

796478

HSH49
Protein HSH49

1

0

High-throughput

0.458

High

523737

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

544635

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

670614

SIS1
Protein SIS1

1

2

High-throughput

0.445

High

675946

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.445

High

741449

HSP7F
Heat shock protein homolog SSE1

1

3

High-throughput

0.445

High

742832

HSP79
Heat shock protein homolog SSE2

1

3

High-throughput

0.445

High

796440

CAJ1
Protein CAJ1

1

2

High-throughput

0.445

High

796442

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

739349

ZUO1
Zuotin

1

2

High-throughput

0.407

High

752184

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.407

High

779533

LHS1
Heat shock protein 70 homolog LHS1

1

2

High-throughput

0.407

High

394491

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.269

Low

738371

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

0

High-throughput

0.269

Low

796473

LSP1
Sphingolipid long chain base-responsive protein LSP1

1

0

High-throughput

0.269

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025