Protein: SAHH
Adenosylhomocysteinase (AdoHcyase) (EC 3.13.2.1) (S-adenosyl-L-homocysteine hydrolase)

Gene: SAHH, SAH1
Organism: Saccharomyces cerevisiae S288C
Interactions: 97
UniProt ID: P39954

Gene Ontology (top 5):
GO:0004013 - adenosylhomocysteinase activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006641 - triglyceride metabolic process
GO:0006656 - phosphatidylcholine biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

815734

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

3

3

High-throughput

0.640

High

815733

CAF16
CCR4-associated factor 16

3

0

High-throughput

0.619

High

670742

SIS1
Protein SIS1

2

0

High-throughput

0.576

High

524034

HSP71
Heat shock protein SSA1

2

2

High-throughput

0.571

High

815725

SSB2
Ribosome-associated molecular chaperone SSB2

2

2

High-throughput

0.552

High

656476

KC11
Casein kinase I homolog 1

1

4

High-throughput

0.536

High

666686

GRR1
SCF E3 ubiquitin ligase complex F-box protein GRR1

1

1

High-throughput

0.536

High

778957

KDX1
Serine/threonine-protein kinase KDX1

1

1

High-throughput

0.536

High

815726

IST3
U2 snRNP component IST3

1

4

High-throughput

0.536

High

815743

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

1

High-throughput

0.536

High

815748

GCN5
Histone acetyltransferase GCN5

1

1

High-throughput

0.536

High

449414

SPT2
Protein SPT2

1

0

High-throughput

0.513

High

815740

BRE5
UBP3-associated protein BRE5

1

0

High-throughput

0.513

High

815741

IGO1
mRNA stability protein IGO1

1

0

High-throughput

0.513

High

441138

KAPA
cAMP-dependent protein kinase type 1

1

2

High-throughput

0.500

High

441366

KAPB
cAMP-dependent protein kinase type 2

1

2

High-throughput

0.500

High

464597

PBS2
MAP kinase kinase PBS2

1

5

High-throughput

0.500

High

555314

EI2BD
Translation initiation factor eIF2B subunit delta

1

1

High-throughput

0.500

High

617397

GBB
Guanine nucleotide-binding protein subunit beta

1

2

High-throughput

0.500

High

622957

CSK22
Casein kinase II subunit alpha'

1

1

High-throughput

0.500

High

628068

FKBP
FK506-binding protein 1

1

3

High-throughput

0.500

High

633470

PP11
Serine/threonine-protein phosphatase PP1-1

1

1

High-throughput

0.500

High

672316

RV161
Reduced viability upon starvation protein 161

1

1

High-throughput

0.500

High

738651

EI2BB
Translation initiation factor eIF2B subunit beta

1

1

High-throughput

0.500

High

814196

RV167
Reduced viability upon starvation protein 167

1

1

High-throughput

0.500

High

815732

RIM15
Serine/threonine-protein kinase RIM15

1

6

High-throughput

0.500

High

815727

EGH1
Ergosteryl-beta-glucosidase

1

0

High-throughput

0.493

High

815749

ERB1
Ribosome biogenesis protein ERB1

1

3

High-throughput

0.489

High

576970

AMPL
Vacuolar aminopeptidase 1

1

0

High-throughput

0.479

High

666187

MEK1
Meiosis-specific serine/threonine-protein kinase MEK1

1

0

High-throughput

0.479

High

737728

IF2G
Eukaryotic translation initiation factor 2 subunit gamma

1

0

High-throughput

0.479

High

751405

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

0

High-throughput

0.479

High

779609

VPS21
Vacuolar protein sorting-associated protein 21

1

0

High-throughput

0.479

High

815729

SA185
SIT4-associating protein SAP185

1

0

High-throughput

0.479

High

815745

IMA1
Importin subunit alpha

1

0

High-throughput

0.479

High

815752

IMH1
Golgin IMH1

1

0

High-throughput

0.479

High

368446

TPIS
Triosephosphate isomerase

1

1

High-throughput

0.479

High

392777

HSP82
ATP-dependent molecular chaperone HSP82

1

2

High-throughput

0.479

High

579441

HSC82
ATP-dependent molecular chaperone HSC82

1

2

High-throughput

0.479

High

679714

CDC48
Cell division control protein 48

1

2

High-throughput

0.479

High

792065

GBLP
Small ribosomal subunit protein RACK1

1

3

Small-scale

0.479

High

795363

ATG8
Autophagy-related protein 8

1

5

High-throughput

0.479

High

795640

UBP13
Ubiquitin carboxyl-terminal hydrolase 13

1

1

High-throughput

0.479

High

815747

TOM1
E3 ubiquitin-protein ligase TOM1

1

3

High-throughput

0.479

High

623863

MYO2
Myosin-2

1

0

Small-scale

0.460

High

359481

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

0

High-throughput

0.458

High

416439

HXKA
Hexokinase-1

1

0

High-throughput

0.458

High

435116

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

441925

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

503061

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.458

High

504229

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.458

High

512457

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.458

High

513025

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.458

High

514653

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

555085

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.458

High

572591

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.458

High

674644

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

689476

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

747871

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

750670

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.458

High

778346

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

803551

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.458

High

806719

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.458

High

812038

DHH1
ATP-dependent RNA helicase DHH1

1

0

High-throughput

0.458

High

812321

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

815731

OTU1
Ubiquitin thioesterase OTU1

1

0

High-throughput

0.458

High

815736

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

815739

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

815744

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

815746

COFI
Cofilin

1

0

High-throughput

0.458

High

815755

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

815756

SGO1
Shugoshin

1

0

High-throughput

0.458

High

815757

MCA1
Metacaspase-1

1

0

High-throughput

0.458

High

625013

PRP6
Pre-mRNA-splicing factor 6

1

1

High-throughput

0.457

High

748177

SUI1
Eukaryotic translation initiation factor eIF-1

1

1

High-throughput

0.457

High

815738

SEH1
Nucleoporin SEH1

1

1

High-throughput

0.457

High

815760

DBP10
ATP-dependent RNA helicase DBP10

1

1

High-throughput

0.437

High

815730

LYS14
Lysine biosynthesis regulatory protein LYS14

1

0

High-throughput

0.282

High

444853

SIR3
Regulatory protein SIR3

1

0

High-throughput

0.279

Low

448172

HAP2
Transcriptional activator HAP2

1

0

High-throughput

0.279

Low

449288

RAD10
DNA repair protein RAD10

1

0

High-throughput

0.279

Low

815750

SEN15
tRNA-splicing endonuclease subunit SEN15

1

0

High-throughput

0.279

Low

815751

YD306
F-box protein YDR306C

1

0

High-throughput

0.279

Low

459096

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

0

High-throughput

0.261

Low

661727

VAN1
Mannan polymerase I complex VAN1 subunit

1

0

High-throughput

0.261

Low

672245

CDC10
Cell division control protein 10

1

0

High-throughput

0.261

Low

815754

PRP11
Pre-mRNA-splicing factor PRP11

1

0

High-throughput

0.261

Low

707170

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

794998

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

803072

GOSR1
Golgi SNAP receptor complex member 1

1

0

High-throughput

0.249

Low

815728

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

815735

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.249

Low

815737

MNN10
Probable alpha-1,6-mannosyltransferase MNN10

1

0

High-throughput

0.249

Low

815742

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.249

Low

815753

NVJ2
Nucleus-vacuole junction protein 2

1

0

High-throughput

0.249

Low

815758

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

815759

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025