Protein: CISY1
Citrate synthase, mitochondrial (EC 2.3.3.1)

Gene: CISY1, CIT1
Organism: Saccharomyces cerevisiae S288C
Interactions: 77
UniProt ID: P00890

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005758 - mitochondrial intermembrane space
GO:0005759 - mitochondrial matrix
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

367342

CISY1
Citrate synthase, mitochondrial

2

10

Small-scale

0.757

High

367355

MDHM
Malate dehydrogenase, mitochondrial

2

7

Small-scale

0.624

High

367391

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

0

High-throughput

0.559

High

367404

UCC1
F-box protein UCC1

2

1

Small-scale

0.533

High

367394

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

2

High-throughput

0.500

High

367348

SIR3
Regulatory protein SIR3

1

0

High-throughput

0.479

High

367359

KC11
Casein kinase I homolog 1

1

0

High-throughput

0.479

High

367381

ATG12
Ubiquitin-like protein ATG12

1

0

High-throughput

0.479

High

367384

RV167
Reduced viability upon starvation protein 167

1

0

High-throughput

0.479

High

367416

RAD59
DNA repair protein RAD59

1

0

High-throughput

0.479

High

367344

COX4
Cytochrome c oxidase subunit 4, mitochondrial

1

2

High-throughput

0.479

High

367347

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.479

High

367350

HSP77
Import motor subunit, mitochondrial

1

5

High-throughput

0.479

High

367351

HSP71
Heat shock protein SSA1

1

5

High-throughput

0.479

High

367352

HSP72
Heat shock protein SSA2

1

5

High-throughput

0.479

High

367362

SIS1
Protein SIS1

1

1

High-throughput

0.479

High

367363

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.479

High

367364

CDC48
Cell division control protein 48

1

5

High-throughput

0.479

High

367366

RL16A
Large ribosomal subunit protein uL13A

1

1

High-throughput

0.479

High

367370

HS104
Heat shock protein 104

1

4

High-throughput

0.479

High

367374

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

1

High-throughput

0.479

High

367379

MIC60
MICOS complex subunit MIC60

1

2

High-throughput

0.479

High

367385

RSP5
E3 ubiquitin-protein ligase RSP5

1

3

High-throughput

0.479

High

367386

FMP10
Uncharacterized mitochondrial membrane protein FMP10

1

1

High-throughput

0.479

High

367400

RM01
Large ribosomal subunit protein uL1m

1

1

High-throughput

0.479

High

367415

RIO1
Serine/threonine-protein kinase RIO1

1

1

High-throughput

0.479

High

367345

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

High-throughput

0.458

High

367346

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.458

High

367358

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.458

High

367375

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

367383

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

367393

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.458

High

367398

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

367402

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

0

High-throughput

0.458

High

367403

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

0

High-throughput

0.458

High

367410

TMA46
Translation machinery-associated protein 46

1

0

High-throughput

0.458

High

367356

GBB
Guanine nucleotide-binding protein subunit beta

1

1

High-throughput

0.457

High

367369

RAD16
DNA repair protein RAD16

1

2

High-throughput

0.457

High

367382

TEM1
Protein TEM1

1

1

High-throughput

0.457

High

367389

IST3
U2 snRNP component IST3

1

2

High-throughput

0.457

High

367343

HSP82
ATP-dependent molecular chaperone HSP82

1

3

High-throughput

0.445

High

367360

MRS4
Mitochondrial RNA-splicing protein MRS4

1

3

High-throughput

0.445

High

367354

CPYI
Carboxypeptidase Y inhibitor

1

2

Small-scale

0.437

High

367368

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

367376

SC61A
Protein transport protein SEC61

1

1

High-throughput

0.437

High

367388

TM108
Protein TMA108

1

2

High-throughput

0.437

High

367407

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.437

High

367380

ANM1
Protein arginine N-methyltransferase 1

1

3

High-throughput

0.417

High

367396

UBC7
Ubiquitin-conjugating enzyme E2 7

1

2

High-throughput

0.417

High

367409

RBX1
RING-box protein HRT1

1

2

High-throughput

0.407

High

367411

CDC53
Cell division control protein 53

1

3

High-throughput

0.407

High

367405

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

2

0

High-throughput

0.310

High

367349

RAD10
DNA repair protein RAD10

1

0

High-throughput

0.261

Low

367357

PRP6
Pre-mRNA-splicing factor 6

1

0

High-throughput

0.261

Low

367361

GRR1
SCF E3 ubiquitin ligase complex F-box protein GRR1

1

0

High-throughput

0.261

Low

367365

RFA3
Replication factor A protein 3

1

0

High-throughput

0.261

Low

367367

YJU2
Splicing factor YJU2

1

0

High-throughput

0.261

Low

367372

CDC12
Cell division control protein 12

1

0

High-throughput

0.261

Low

367377

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

0

High-throughput

0.261

Low

367378

SLD2
DNA replication regulator SLD2

1

0

High-throughput

0.261

Low

367387

RAD26
DNA repair and recombination protein RAD26

1

0

High-throughput

0.261

Low

367390

COPB2
Coatomer subunit beta'

1

0

High-throughput

0.261

Low

367395

CIK1
Spindle pole body-associated protein CIK1

1

0

High-throughput

0.261

Low

367401

SEN15
tRNA-splicing endonuclease subunit SEN15

1

0

High-throughput

0.261

Low

367406

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

1

0

High-throughput

0.261

Low

367408

BUD20
Bud site selection protein 20

1

0

High-throughput

0.261

Low

367353

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.249

Low

367371

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.249

Low

367373

SPT16
FACT complex subunit SPT16

1

0

High-throughput

0.249

Low

367392

SKP1
Suppressor of kinetochore protein 1

1

0

High-throughput

0.249

Low

367397

PML39
Pre-mRNA leakage protein 39

1

0

High-throughput

0.249

Low

367412

HFI1
SAGA complex subunit HFI1

1

0

Small-scale

0.249

Low

367413

YG11A
Transposon Ty1-GR1 Gag polyprotein

1

0

High-throughput

0.249

Low

367414

RGL1
RHO1 GEF localizing protein 1

1

0

High-throughput

0.249

Low

367417

DBP10
ATP-dependent RNA helicase DBP10

1

0

High-throughput

0.249

Low

367399

HSP31
Glutathione-independent glyoxalase HSP31

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025