Protein: RIF1
Telomere length regulator protein RIF1 (RAP1-interacting factor 1)

Gene: RIF1
Organism: Saccharomyces cerevisiae S288C
Interactions: 53
UniProt ID: P29539

Gene Ontology (top 5):
GO:0000723 - telomere maintenance
GO:0000729 - DNA double-strand break processing
GO:0000781 - chromosome, telomeric region
GO:0000979 - RNA polymerase II core promoter sequence-specific DNA binding
GO:0003688 - DNA replication origin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

550034

RAP1
DNA-binding protein RAP1

7

0

Small-scale

0.718

High

713575

PP12
Serine/threonine-protein phosphatase PP1-2

5

0

Small-scale

0.679

High

713571

RIF1
Telomere length regulator protein RIF1

2

0

Small-scale

0.585

High

713587

CDC14
Tyrosine-protein phosphatase CDC14

2

0

High-throughput

0.585

High

713573

DBF4
DDK kinase regulatory subunit DBF4

2

0

Small-scale

0.559

High

444747

SIR2
NAD-dependent histone deacetylase SIR2

1

0

High-throughput

0.513

High

585873

CSK21
Casein kinase II subunit alpha

1

0

High-throughput

0.513

High

713578

BYE1
Transcription factor BYE1

1

0

High-throughput

0.493

High

713593

NOC4
Nucleolar complex protein 4

1

0

High-throughput

0.493

High

713592

RIF2
Protein RIF2

1

0

Small-scale

0.484

High

440911

CDC7
Cell division control protein 7

1

0

Small-scale

0.480

High

419378

H2A1
Histone H2A.1

1

1

High-throughput

0.479

High

419639

H2A2
Histone H2A.2

1

1

High-throughput

0.479

High

713598

H2AZ
Histone H2A.Z

1

2

Small-scale

0.479

High

381928

H4
Histone H4

1

0

High-throughput

0.458

High

488929

SWI6
Regulatory protein SWI6

1

0

High-throughput

0.458

High

668251

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

0

High-throughput

0.458

High

706415

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

712949

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.458

High

713574

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

0

High-throughput

0.458

High

713576

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

713585

RNH2A
Ribonuclease H2 subunit A

1

0

Small-scale

0.458

High

713586

H3
Histone H3

1

0

High-throughput

0.458

High

713588

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

713589

LRS4
Monopolin complex subunit LRS4

1

0

Small-scale

0.458

High

713596

TSR3
18S rRNA aminocarboxypropyltransferase

1

0

High-throughput

0.458

High

713597

NDJ1
Non-disjunction protein 1

1

0

Small-scale

0.458

High

713599

SUS1
SAGA complex subunit SUS1

1

0

Small-scale

0.458

High

713600

MEX67
mRNA export factor MEX67

1

0

High-throughput

0.458

High

523283

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

526115

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

544079

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

675782

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.445

High

712753

PTP2
Tyrosine-protein phosphatase 2

1

1

High-throughput

0.445

High

713579

XDJ1
DnaJ protein homolog XDJ1

1

1

High-throughput

0.445

High

713581

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

392367

HSP82
ATP-dependent molecular chaperone HSP82

1

0

High-throughput

0.426

High

653832

HSP12
12 kDa heat shock protein

1

0

High-throughput

0.426

High

713572

HS104
Heat shock protein 104

1

0

High-throughput

0.426

High

577053

SEC63
Protein translocation protein SEC63

1

1

High-throughput

0.407

High

668422

PTP1
Tyrosine-protein phosphatase 1

1

0

High-throughput

0.279

Low

713595

PSR2
Probable phosphatase PSR2

1

0

High-throughput

0.279

Low

541146

SYLM
Leucine--tRNA ligase, mitochondrial

1

0

High-throughput

0.269

Low

646638

VPS15
Serine/threonine-protein kinase VPS15

1

0

High-throughput

0.249

Low

713577

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.249

Low

713582

BNI1
Protein BNI1

1

0

High-throughput

0.249

Low

713583

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

0

High-throughput

0.249

Low

713594

YD073
UPF0592 protein YDL073W

1

0

High-throughput

0.249

Low

713580

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.232

Low

713584

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.232

Low

713590

HSP31
Glutathione-independent glyoxalase HSP31

1

0

High-throughput

0.232

Low

713591

PFD5
Prefoldin subunit 5

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025