Protein: RAP1
DNA-binding protein RAP1 (Repressor/activator site-binding protein) (SBF-E) (TUF)

Gene: RAP1
Organism: Saccharomyces cerevisiae S288C
Interactions: 97
UniProt ID: P11938

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000228 - nuclear chromosome
GO:0000723 - telomere maintenance
GO:0000781 - chromosome, telomeric region
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

550025

SNF2
Transcription regulatory protein SNF2

2

2

Small-scale

0.799

High

550039

SWI3
SWI/SNF complex subunit SWI3

1

1

Small-scale

0.757

High

444820

SIR3
Regulatory protein SIR3

8

0

Small-scale

0.726

High

550081

RIF2
Protein RIF2

8

0

Small-scale

0.723

High

550019

SIR4
Regulatory protein SIR4

7

0

Small-scale

0.722

High

550034

RIF1
Telomere length regulator protein RIF1

7

0

Small-scale

0.718

High

454029

GCR1
Glycolytic genes transcriptional activator GCR1

4

0

Small-scale

0.665

High

550063

TAF4
Transcription initiation factor TFIID subunit 4

3

0

Small-scale

0.645

High

381824

H4
Histone H4

4

0

Small-scale

0.643

High

550050

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

3

0

Small-scale

0.628

High

550045

SPT10
Protein SPT10

1

0

High-throughput

0.586

High

550069

HDA1
Histone deacetylase HDA1

1

0

Small-scale

0.586

High

550040

STH1
Nuclear protein STH1/NPS1

2

2

Small-scale

0.585

High

550020

TBP
TATA-box-binding protein

2

0

Small-scale

0.577

High

550060

RSC8
Chromatin structure-remodeling complex protein RSC8

1

1

High-throughput

0.575

High

395216

GCN4
General control transcription factor GCN4

1

0

Small-scale

0.571

High

550085

ESA1
Histone acetyltransferase ESA1

1

0

Small-scale

0.561

High

550071

H3
Histone H3

2

0

Small-scale

0.560

High

550090

SMT3
Ubiquitin-like protein SMT3

2

0

Small-scale

0.559

High

525760

HSP72
Heat shock protein SSA2

2

1

High-throughput

0.552

High

550061

TAF1
Transcription initiation factor TFIID subunit 1

2

0

Small-scale

0.547

High

550018

RAP1
DNA-binding protein RAP1

1

0

High-throughput

0.546

High

550075

TBF1
Protein TBF1

1

0

High-throughput

0.546

High

550038

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.536

High

380934

H2B1
Histone H2B.1

2

0

High-throughput

0.528

High

543612

SSB1
Ribosome-associated molecular chaperone SSB1

2

0

High-throughput

0.528

High

550056

IFH1
Protein IFH1

1

0

Small-scale

0.513

High

550057

FKHL1
Pre-rRNA-processing protein FHL1

1

0

Small-scale

0.513

High

550076

TAF12
SAGA complex/transcription factor TFIID complex subunit TAF12

1

0

Small-scale

0.513

High

550048

ATM
Serine/threonine-protein kinase TEL1

1

1

Small-scale

0.501

High

550049

ATR
Serine/threonine-protein kinase MEC1

1

1

Small-scale

0.501

High

550065

INO80
Chromatin-remodeling ATPase INO80

1

1

Small-scale

0.501

High

550024

SNF6
Transcription regulatory protein SNF6

1

0

Small-scale

0.494

High

550064

TAF6
SAGA complex/transcription factor TFIID complex subunit TAF6

1

0

Small-scale

0.494

High

547750

NHP6A
Non-histone chromosomal protein 6A

1

1

Small-scale

0.481

High

547842

NHP6B
Non-histone chromosomal protein 6B

1

1

Small-scale

0.481

High

419337

H2A1
Histone H2A.1

1

1

High-throughput

0.479

High

419569

H2A2
Histone H2A.2

1

1

High-throughput

0.479

High

550046

BDF1
Bromodomain-containing factor 1

1

1

Small-scale

0.479

High

550078

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.479

High

408384

GAL4
Regulatory protein GAL4

1

0

Small-scale

0.460

High

448274

PDE2
3',5'-cyclic-nucleotide phosphodiesterase 2

1

0

High-throughput

0.458

High

550023

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

550026

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.458

High

550031

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

550036

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

550043

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

550053

UME6
Transcriptional regulatory protein UME6

1

0

High-throughput

0.458

High

550058

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

550068

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

550072

GCR2
Glycolytic genes transcriptional activator GCR2

1

0

Small-scale

0.458

High

550073

PRS8
26S proteasome regulatory subunit 8 homolog

1

0

Small-scale

0.458

High

550080

LRS4
Monopolin complex subunit LRS4

1

0

Small-scale

0.458

High

550082

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

550087

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

550089

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

550092

NDJ1
Non-disjunction protein 1

1

0

Small-scale

0.458

High

550096

CMR1
DNA damage-binding protein CMR1

1

0

High-throughput

0.458

High

522868

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

550027

MCM3
DNA replication licensing factor MCM3

1

2

High-throughput

0.445

High

550032

MCM2
DNA replication licensing factor MCM2

1

2

High-throughput

0.445

High

550033

MCM5
Minichromosome maintenance protein 5

1

1

High-throughput

0.445

High

550037

ZUO1
Zuotin

1

1

High-throughput

0.445

High

550079

HMO1
High mobility group protein 1

1

2

High-throughput

0.445

High

550086

ISW2
ISWI chromatin-remodeling complex ATPase ISW2

1

2

High-throughput

0.445

High

550094

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.445

High

550088

SAS10
Something about silencing protein 10

1

0

High-throughput

0.438

High

394162

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

550022

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.426

High

550029

SIS1
Protein SIS1

1

0

High-throughput

0.426

High

550030

CDC48
Cell division control protein 48

1

0

High-throughput

0.426

High

550041

RSC7
Chromatin structure-remodeling complex subunit RSC7

1

0

High-throughput

0.426

High

550047

SET3
SET domain-containing protein 3

1

0

High-throughput

0.426

High

550052

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.426

High

550055

CAJ1
Protein CAJ1

1

0

High-throughput

0.426

High

550059

AZF1
Transcription factor AZF1

1

0

High-throughput

0.426

High

550066

ITC1
Imitation switch two complex protein 1

1

0

High-throughput

0.426

High

550067

SNF12
Transcription regulatory protein SNF12

1

0

High-throughput

0.426

High

550084

RSC58
Chromatin structure-remodeling complex protein RSC58

1

0

High-throughput

0.426

High

550095

CAF1A
Chromatin assembly factor 1 subunit A

1

0

High-throughput

0.426

High

550074

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

2

High-throughput

0.407

High

550083

RSC2
Chromatin structure-remodeling complex subunit RSC2

1

4

High-throughput

0.407

High

550051

NU170
Nucleoporin NUP170

1

0

Small-scale

0.279

Low

550077

NUP53
Nucleoporin NUP53

1

0

Small-scale

0.279

Low

550091

HSP42
Heat shock protein 42

1

0

Small-scale

0.265

Low

550035

CCR4
CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4

1

0

Small-scale

0.261

Low

550070

ZDS2
Protein ZDS2

1

0

Small-scale

0.251

Low

550021

ACOX
Acyl-coenzyme A oxidase

1

0

High-throughput

0.249

Low

550042

ATO2
Ammonia transport outward protein 2

1

0

High-throughput

0.249

Low

550093

DBP10
ATP-dependent RNA helicase DBP10

1

0

High-throughput

0.249

Low

550028

TSR4
20S rRNA accumulation protein 4

1

0

High-throughput

0.238

Low

358099

ADH1
Alcohol dehydrogenase 1

1

0

High-throughput

0.232

Low

427107

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.232

Low

550044

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low

550054

TCPZ
T-complex protein 1 subunit zeta

1

0

High-throughput

0.232

Low

550062

HLJ1
Protein HLJ1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025