Protein: SLD2
DNA replication regulator SLD2 (DNA replication and checkpoint protein 1)

Gene: SLD2
Organism: Saccharomyces cerevisiae S288C
Interactions: 49
UniProt ID: P34252

Gene Ontology (top 5):
GO:0000727 - double-strand break repair via break-induced replication
GO:0003688 - DNA replication origin binding
GO:0003697 - single-stranded DNA binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

758508

DPB11
DNA replication regulator DPB11

13

1

Small-scale

0.763

High

364459

CDK1
Cyclin-dependent kinase 1

4

1

Small-scale

0.698

High

712963

MCM2
DNA replication licensing factor MCM2

3

3

Small-scale

0.670

High

718935

CGS5
S-phase entry cyclin-5

2

2

Small-scale

0.595

High

721362

MCM4
DNA replication licensing factor MCM4

2

4

Small-scale

0.595

High

642031

DPOE
DNA polymerase epsilon catalytic subunit A

2

0

Small-scale

0.569

High

758518

PSF1
DNA replication complex GINS protein PSF1

2

0

Small-scale

0.559

High

358403

ADH2
Alcohol dehydrogenase 2

1

0

High-throughput

0.513

High

366791

IPYR
Inorganic pyrophosphatase

1

0

High-throughput

0.513

High

470026

GAL7
Galactose-1-phosphate uridylyltransferase

1

0

High-throughput

0.513

High

487955

TRNL
tRNA ligase

1

0

High-throughput

0.513

High

578225

TAL1
Transaldolase

1

0

High-throughput

0.513

High

585897

CSK21
Casein kinase II subunit alpha

1

0

High-throughput

0.513

High

604936

MDHM
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.513

High

758514

IMA1
Importin subunit alpha

1

0

High-throughput

0.513

High

758502

DMA1
E3 ubiquitin-protein ligase DMA1

1

0

Small-scale

0.504

High

440926

CDC7
Cell division control protein 7

1

2

Small-scale

0.501

High

664428

MCM3
DNA replication licensing factor MCM3

1

3

Small-scale

0.501

High

713257

MCM5
Minichromosome maintenance protein 5

1

3

Small-scale

0.501

High

758499

MCM7
DNA replication licensing factor MCM7

1

1

Small-scale

0.501

High

758509

MCM6
DNA replication licensing factor MCM6

1

3

Small-scale

0.501

High

758513

CDC14
Tyrosine-protein phosphatase CDC14

1

1

Small-scale

0.501

High

740647

CBS
Cystathionine beta-synthase

1

0

High-throughput

0.493

High

758503

LSM12
Protein LSM12

1

0

High-throughput

0.493

High

758507

SYEC
Glutamate--tRNA ligase, cytoplasmic

1

0

High-throughput

0.493

High

460720

CDC4
Cell division control protein 4

1

0

Small-scale

0.480

High

642359

MCK1
Protein kinase MCK1

1

0

Small-scale

0.480

High

739945

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

1

0

Small-scale

0.480

High

758510

SLD3
DNA replication regulator SLD3

1

0

Small-scale

0.480

High

758516

SLD7
Mitochondrial morphogenesis protein SLD7

1

0

Small-scale

0.480

High

626680

HSP60
Heat shock protein 60, mitochondrial

1

0

High-throughput

0.479

High

758506

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.479

High

665174

DPB2
DNA polymerase epsilon subunit B

1

1

Small-scale

0.479

High

758515

SLD5
DNA replication complex GINS protein SLD5

1

0

Small-scale

0.458

High

758517

PST2
Protoplast secreted protein 2

1

0

Small-scale

0.458

High

523539

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

526336

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

741300

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

510364

HSP77
Import motor subunit, mitochondrial

1

0

High-throughput

0.426

High

544377

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

758505

MAM33
Mitochondrial acidic protein MAM33

2

0

High-throughput

0.324

High

758512

PEX13
Peroxisomal membrane protein PEX13

1

0

High-throughput

0.282

High

518717

ADH4
Alcohol dehydrogenase 4

1

0

High-throughput

0.279

Low

758500

GRPE
GrpE protein homolog, mitochondrial

1

0

High-throughput

0.279

Low

758501

PP2C7
Protein phosphatase 2C homolog 7, mitochondrial

1

0

High-throughput

0.279

Low

758504

DSS1
Exoribonuclease II, mitochondrial

1

0

High-throughput

0.279

Low

758511

COPA
Coatomer subunit alpha

1

0

High-throughput

0.279

Low

367378

CISY1
Citrate synthase, mitochondrial

1

0

High-throughput

0.261

Low

425121

OTC
Ornithine carbamoyltransferase

1

0

High-throughput

0.261

Low


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Last updated: 11Aug2025