Protein: RPPH
RNA pyrophosphohydrolase (EC 3.6.1.-) ((Di)nucleoside polyphosphate hydrolase) (Ap5A pyrophosphatase)

Gene: RPPH
Organism: Escherichia coli K-12
Interactions: 58
UniProt ID: P0A776

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0005737 - cytoplasm
GO:0006402 - mRNA catabolic process
GO:0008033 - tRNA processing
GO:0016818 - hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

490420

DAPF
Diaminopimelate epimerase

2

0

High-throughput

0.635

High

491923

RS4
Small ribosomal subunit protein uS4

3

0

High-throughput

0.629

High

491939

RL17
Large ribosomal subunit protein bL17

3

0

High-throughput

0.629

High

491950

RL2
Large ribosomal subunit protein uL2

2

1

High-throughput

0.612

High

491951

RL3
Large ribosomal subunit protein uL3

2

0

High-throughput

0.585

High

382545

RS6
Small ribosomal subunit protein bS6

2

0

High-throughput

0.563

High

383990

RL15
Large ribosomal subunit protein uL15

2

0

High-throughput

0.563

High

491915

RL28
Large ribosomal subunit protein bL28

2

0

High-throughput

0.563

High

491917

RS13
Small ribosomal subunit protein uS13

2

0

High-throughput

0.563

High

491918

RS18
Small ribosomal subunit protein bS18

2

0

High-throughput

0.563

High

491919

RS19
Small ribosomal subunit protein uS19

2

0

High-throughput

0.563

High

491920

RS20
Small ribosomal subunit protein bS20

2

0

High-throughput

0.563

High

491922

RS3
Small ribosomal subunit protein uS3

2

0

High-throughput

0.563

High

491937

RL16
Large ribosomal subunit protein uL16

2

0

High-throughput

0.563

High

491940

RL21
Large ribosomal subunit protein bL21

2

0

High-throughput

0.563

High

491945

RNR
Ribonuclease R

2

0

High-throughput

0.563

High

491952

RL24
Large ribosomal subunit protein uL24

2

0

High-throughput

0.563

High

491957

RL25
Large ribosomal subunit protein bL25

2

0

High-throughput

0.563

High

491958

RLMKL
Ribosomal RNA large subunit methyltransferase K/L [Includes: 23S rRNA m2G2445 methyltransferase

2

0

High-throughput

0.563

High

491930

RLUC
Ribosomal large subunit pseudouridine synthase C

2

1

High-throughput

0.537

High

491932

DBHA
DNA-binding protein HU-alpha

2

1

High-throughput

0.537

High

491948

RLUB
Ribosomal large subunit pseudouridine synthase B

2

1

High-throughput

0.537

High

489484

CH60
Chaperonin GroEL

1

1

High-throughput

0.536

High

491955

FLAV
Flavodoxin 1

1

0

High-throughput

0.518

High

491925

RS9
Small ribosomal subunit protein uS9

1

0

High-throughput

0.513

High

491959

YNAE
Uncharacterized protein YnaE

1

1

High-throughput

0.489

High

491960

YDFK
Cold shock protein YdfK

1

1

High-throughput

0.489

High

382634

RS7
Small ribosomal subunit protein uS7

1

0

High-throughput

0.464

High

491911

RL10
Large ribosomal subunit protein uL10

1

0

High-throughput

0.464

High

491912

RL19
Large ribosomal subunit protein bL19

1

0

High-throughput

0.464

High

491913

RL1
Large ribosomal subunit protein uL1

1

0

High-throughput

0.464

High

491914

RL20
Large ribosomal subunit protein bL20

1

0

High-throughput

0.464

High

491916

RL9
Large ribosomal subunit protein bL9

1

0

High-throughput

0.464

High

491921

RS2
Small ribosomal subunit protein uS2

1

0

High-throughput

0.464

High

491924

RS5
Small ribosomal subunit protein uS5

1

0

High-throughput

0.464

High

491929

RL13
Large ribosomal subunit protein uL13

1

0

High-throughput

0.464

High

491936

RL14
Large ribosomal subunit protein uL14

1

0

High-throughput

0.464

High

491941

RL6
Large ribosomal subunit protein uL6

1

0

High-throughput

0.464

High

491942

RS1
Small ribosomal subunit protein bS1

1

0

High-throughput

0.464

High

491944

RL18
Large ribosomal subunit protein uL18

1

0

High-throughput

0.464

High

491953

RL4
Large ribosomal subunit protein uL4

1

0

High-throughput

0.464

High

491954

RL22
Large ribosomal subunit protein uL22

1

0

High-throughput

0.464

High

491956

RL5
Large ribosomal subunit protein uL5

1

0

High-throughput

0.464

High

491569

KPRS
Ribose-phosphate pyrophosphokinase

1

0

High-throughput

0.458

High

491946

SRMB
ATP-dependent RNA helicase SrmB

1

1

High-throughput

0.442

High

491933

DBHB
DNA-binding protein HU-beta

1

1

High-throughput

0.437

High

450115

SDHB
Succinate dehydrogenase iron-sulfur subunit

1

2

High-throughput

0.417

High

491931

FRDB
Fumarate reductase iron-sulfur subunit

1

2

High-throughput

0.417

High

491928

DEAD
ATP-dependent RNA helicase DeaD

2

0

High-throughput

0.307

High

491961

ZINT
Metal-binding protein ZinT

1

0

High-throughput

0.282

High

491927

SLYD
FKBP-type peptidyl-prolyl cis-trans isomerase SlyD

1

0

High-throughput

0.279

Low

491934

RSPR
HTH-type transcriptional repressor RspR

1

0

High-throughput

0.279

Low

491947

XAPR
HTH-type transcriptional regulator XapR

1

0

High-throughput

0.279

Low

491949

RTCB
RNA-splicing ligase RtcB

1

0

High-throughput

0.279

Low

491926

YAJQ
Nucleotide-binding protein YajQ

1

0

High-throughput

0.253

Low

491938

SPOT
Bifunctional

1

0

High-throughput

0.253

Low

491943

YFIF
Uncharacterized tRNA/rRNA methyltransferase YfiF

1

0

High-throughput

0.253

Low

491935

YIBL
Uncharacterized protein YibL

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025