Protein: SPC19
DASH complex subunit SPC19 (19 kDa spindle pole component protein) (Outer kinetochore protein SPC19)

Gene: SPC19
Organism: Saccharomyces cerevisiae S288C
Interactions: 57
UniProt ID: Q03954

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005876 - spindle microtubule
GO:0008608 - attachment of spindle microtubules to kinetochore
GO:0031116 - positive regulation of microtubule polymerization
GO:0042729 - DASH complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

781916

SPC34
DASH complex subunit SPC34

17

0

Small-scale

0.933

High

919103

DAM1
DASH complex subunit DAM1

6

0

Small-scale

0.896

High

782593

DAD2
DASH complex subunit DAD2

6

0

Small-scale

0.893

High

999590

HSK3
DASH complex subunit HSK3

6

0

Small-scale

0.884

High

917911

DUO1
DASH complex subunit DUO1

4

0

Small-scale

0.838

High

1044559

DAD1
DASH complex subunit DAD1

7

0

Small-scale

0.712

High

776710

ASK1
DASH complex subunit ASK1

6

0

Small-scale

0.691

High

999579

DAD4
DASH complex subunit DAD4

5

0

Small-scale

0.678

High

826797

DSN1
Kinetochore-associated protein DSN1

5

0

Small-scale

0.669

High

755292

NUF2
Kinetochore protein NUF2

3

0

Small-scale

0.627

High

1044552

SPC19
DASH complex subunit SPC19

3

0

High-throughput

0.617

High

824869

NDC80
Kinetochore protein NDC80

3

0

Small-scale

0.614

High

809225

END3
Actin cytoskeleton-regulatory complex protein END3

2

0

High-throughput

0.570

High

1044561

GIN4
Serine/threonine-protein kinase GIN4

2

0

High-throughput

0.570

High

1039028

IMA1
Importin subunit alpha

1

0

High-throughput

0.518

High

546136

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.513

High

747755

SMC1
Structural maintenance of chromosomes protein 1

1

0

High-throughput

0.486

High

1044560

RPN5
26S proteasome regulatory subunit RPN5

1

0

High-throughput

0.486

High

735668

SMY1
Kinesin-related protein SMY1

1

0

High-throughput

0.460

High

780983

SPC42
Spindle pole body component SPC42

1

0

High-throughput

0.460

High

822467

TBP6
Probable 26S proteasome subunit YTA6

1

0

High-throughput

0.460

High

827006

MET28
Transcriptional activator of sulfur metabolism MET28

1

0

High-throughput

0.460

High

924898

AF9
Protein AF-9 homolog

1

0

High-throughput

0.460

High

1044555

MDM36
Mitochondrial distribution and morphology protein 36

1

0

High-throughput

0.460

High

1044557

ADY3
Accumulates dyads protein 3

1

0

High-throughput

0.460

High

1044562

GYP5
GTPase-activating protein GYP5

1

0

High-throughput

0.460

High

797905

CENPU
Inner kinetochore subunit AME1

1

0

High-throughput

0.458

High

816975

BIM1
Protein BIM1

1

0

Small-scale

0.458

High

850693

CENPT
Inner kinetochore subunit CNN1

1

0

Small-scale

0.458

High

999573

DAD3
DASH complex subunit DAD3

1

0

High-throughput

0.458

High

1044271

FIN1
Filament protein FIN1

1

0

Small-scale

0.458

High

1044558

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

525034

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

527585

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

742321

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

580004

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.426

High

736044

SP110
Spindle pole body component 110

1

0

Small-scale

0.426

High

804426

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.426

High

1044563

CENPI
Inner kinetochore subunit CTF3

1

0

High-throughput

0.426

High

743880

YEF3
Uncharacterized protein YEL043W

2

0

High-throughput

0.310

High

758142

CASP
Protein CASP

2

0

High-throughput

0.310

High

1025026

NUM1
Nuclear migration protein NUM1

2

0

High-throughput

0.310

High

574924

SAM35
Sorting assembly machinery 35 kDa subunit

1

0

High-throughput

0.265

Low

600713

SEC2
Rab guanine nucleotide exchange factor SEC2

1

0

High-throughput

0.251

Low

749718

TYE7
Transcription factor TYE7

1

0

High-throughput

0.251

Low

758487

SEG2
Eisosome protein SEG2

1

0

High-throughput

0.251

Low

776761

YKF0
Uncharacterized protein YKL050C

1

0

High-throughput

0.251

Low

817755

TSC11
Target of rapamycin complex 2 subunit TSC11

1

0

High-throughput

0.251

Low

826068

ULP2
Ubiquitin-like-specific protease 2

1

0

High-throughput

0.251

Low

843268

KRI1
Protein KRI1

1

0

High-throughput

0.251

Low

849703

FMP32
Protein FMP32, mitochondrial

1

0

High-throughput

0.251

Low

1043807

RCF1
Respiratory supercomplex factor 1, mitochondrial

1

0

High-throughput

0.251

Low

1044553

HDA2
HDA1 complex subunit 2

1

0

High-throughput

0.251

Low

1044556

YET3
Endoplasmic reticulum transmembrane protein 3

1

0

High-throughput

0.251

Low

708074

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

1044554

RM35
Large ribosomal subunit protein mL38

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025