Protein: KRI1
Protein KRI1 (KRR1-interacting protein 1)

Gene: KRI1
Organism: Saccharomyces cerevisiae S288C
Interactions: 137
UniProt ID: P42846

Gene Ontology (top 5):
GO:0000447 - endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0005730 - nucleolus
GO:0030686 - 90S preribosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

677452

KRR1
KRR1 small subunit processome component

6

2

Small-scale

0.733

High

798245

ENP1
Essential nuclear protein 1

3

0

High-throughput

0.628

High

435166

RS3
Small ribosomal subunit protein uS3

2

1

High-throughput

0.611

High

436023

RS13
Small ribosomal subunit protein uS15

2

1

High-throughput

0.611

High

441973

RS14A
Small ribosomal subunit protein uS11A

2

2

High-throughput

0.611

High

747430

RSSA1
Small ribosomal subunit protein uS2A

2

2

High-throughput

0.611

High

792103

GBLP
Small ribosomal subunit protein RACK1

3

2

High-throughput

0.609

High

843273

RRP5
rRNA biogenesis protein RRP5

2

0

High-throughput

0.585

High

513069

RS8A
Small ribosomal subunit protein eS8A

2

1

High-throughput

0.584

High

524283

HSP71
Heat shock protein SSA1

3

1

High-throughput

0.578

High

751423

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

2

0

High-throughput

0.576

High

843288

YRA1
RNA annealing protein YRA1

2

2

Small-scale

0.549

High

435586

RS9B
Small ribosomal subunit protein uS4B

1

2

High-throughput

0.536

High

585967

CSK21
Casein kinase II subunit alpha

1

1

High-throughput

0.536

High

811995

RS14B
Small ribosomal subunit protein uS11B

1

2

High-throughput

0.536

High

585299

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

1

High-throughput

0.515

High

738218

NHP2
H/ACA ribonucleoprotein complex subunit NHP2

1

1

High-throughput

0.515

High

843248

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

1

High-throughput

0.515

High

843266

HAS1
ATP-dependent RNA helicase HAS1

1

2

High-throughput

0.515

High

843292

NOP56
Nucleolar protein 56

1

2

High-throughput

0.515

High

688912

RS5
Small ribosomal subunit protein uS7

1

0

High-throughput

0.513

High

843254

NOP13
Nucleolar protein 13

1

0

High-throughput

0.513

High

843255

NAT10
RNA cytidine acetyltransferase

1

0

High-throughput

0.513

High

843281

NOP6
Nucleolar protein 6

1

0

High-throughput

0.513

High

843294

RRP12
Ribosomal RNA-processing protein 12

1

0

High-throughput

0.513

High

843296

NOP14
Nucleolar complex protein 14

1

0

High-throughput

0.513

High

545264

SSB1
Ribosome-associated molecular chaperone SSB1

2

1

High-throughput

0.504

High

843290

UTP23
rRNA-processing protein UTP23

1

1

Small-scale

0.501

High

632570

DBP3
ATP-dependent RNA helicase DBP3

1

0

High-throughput

0.493

High

700250

GAR1
H/ACA ribonucleoprotein complex subunit GAR1

1

0

High-throughput

0.493

High

817247

EDC2
Enhancer of mRNA-decapping protein 2

1

0

High-throughput

0.493

High

843279

TSR1
Ribosome biogenesis protein TSR1

1

0

High-throughput

0.493

High

419445

H2A1
Histone H2A.1

1

5

High-throughput

0.489

High

459111

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

1

High-throughput

0.489

High

645452

XRN1
5'-3' exoribonuclease 1

1

1

High-throughput

0.489

High

676736

GBP2
Serine/arginine

1

2

High-throughput

0.489

High

802091

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

1

High-throughput

0.489

High

843244

RS10B
Small ribosomal subunit protein eS10B

1

2

High-throughput

0.489

High

843247

IMDH4
Inosine-5'-monophosphate dehydrogenase 4

1

1

High-throughput

0.489

High

843253

BRE5
UBP3-associated protein BRE5

1

2

High-throughput

0.489

High

843260

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

2

High-throughput

0.489

High

149823

RS9A
Small ribosomal subunit protein uS4A

1

2

High-throughput

0.479

High

512499

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.479

High

674685

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.479

High

682317

SPB4
ATP-dependent rRNA helicase SPB4

1

1

High-throughput

0.479

High

843274

UTP21
U3 small nucleolar RNA-associated protein 21

1

1

Small-scale

0.479

High

843277

NOC4
Nucleolar complex protein 4

1

2

High-throughput

0.479

High

843278

UTP4
U3 small nucleolar RNA-associated protein 4

1

3

Small-scale

0.479

High

843289

MAK21
Ribosome biogenesis protein MAK21

1

2

High-throughput

0.479

High

843291

DBP10
ATP-dependent RNA helicase DBP10

1

2

High-throughput

0.479

High

843293

NOP58
Nucleolar protein 58

1

2

High-throughput

0.479

High

843263

SKI8
Antiviral protein SKI8

1

2

High-throughput

0.470

High

512098

RS4A
Small ribosomal subunit protein eS4A

1

0

High-throughput

0.458

High

513878

RS11B
Small ribosomal subunit protein uS17B

1

0

High-throughput

0.458

High

514686

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

672902

RRP43
Exosome complex component RRP43

1

0

High-throughput

0.458

High

689520

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

740730

SRP40
Suppressor protein SRP40

1

0

High-throughput

0.458

High

753432

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.458

High

758225

URB1
Nucleolar pre-ribosomal-associated protein 1

1

0

Small-scale

0.458

High

843243

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.458

High

843250

PESC
Pescadillo homolog

1

0

High-throughput

0.458

High

843251

PXR1
Protein PXR1

1

0

High-throughput

0.458

High

843264

TOM1
E3 ubiquitin-protein ligase TOM1

1

0

High-throughput

0.458

High

843265

TMA23
Protein TMA23

1

0

High-throughput

0.458

High

843270

DHR1
Probable ATP-dependent RNA helicase DHR1

1

0

High-throughput

0.458

High

843272

UTP14
U3 small nucleolar RNA-associated protein 14

1

0

High-throughput

0.458

High

843287

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.458

High

843295

EFG1P
rRNA-processing protein EFG1

1

0

High-throughput

0.458

High

427324

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.445

High

548706

RNA1
Ran GTPase-activating protein 1

1

1

High-throughput

0.439

High

822453

TBP6
Probable 26S proteasome subunit YTA6

1

1

High-throughput

0.439

High

843252

PRS10
26S proteasome subunit RPT4

1

1

High-throughput

0.439

High

403548

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

1

Small-scale

0.437

High

410191

RL25
Large ribosomal subunit protein uL23

1

1

High-throughput

0.437

High

419775

H2A2
Histone H2A.2

1

5

High-throughput

0.437

High

433700

RL26A
Large ribosomal subunit protein uL24A

1

2

High-throughput

0.437

High

455119

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.437

High

504269

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.437

High

594423

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

High-throughput

0.437

High

644941

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

1

High-throughput

0.437

High

646440

RAD53
Serine/threonine-protein kinase RAD53

1

1

High-throughput

0.437

High

745783

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

1

High-throughput

0.437

High

824730

MLP2
Protein MLP2

1

1

High-throughput

0.437

High

843257

H3
Histone H3

1

2

High-throughput

0.437

High

843262

XRN2
5'-3' exoribonuclease 2

1

1

High-throughput

0.437

High

843285

RS10A
Small ribosomal subunit protein eS10A

1

2

High-throughput

0.437

High

782359

RPF2
Ribosome biogenesis protein RPF2

1

0

High-throughput

0.426

High

843258

SEN1
Helicase SEN1

1

0

Small-scale

0.426

High

570053

RL3
Large ribosomal subunit protein uL3

1

1

High-throughput

0.407

High

597180

BIP
Endoplasmic reticulum chaperone BiP

1

2

High-throughput

0.407

High

684759

RL5
Large ribosomal subunit protein uL18

1

1

High-throughput

0.407

High

741790

HSP7F
Heat shock protein homolog SSE1

1

5

High-throughput

0.407

High

819036

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.407

High

802232

RS20
Small ribosomal subunit protein uS10

2

0

High-throughput

0.318

High

392904

HSP82
ATP-dependent molecular chaperone HSP82

2

0

High-throughput

0.305

High

826584

DSN1
Kinetochore-associated protein DSN1

2

0

High-throughput

0.305

High

382163

H4
Histone H4

2

0

High-throughput

0.298

High

830034

PMP2
Plasma membrane ATPase proteolipid 2

1

0

High-throughput

0.282

High

454455

PHO4
Phosphate system positive regulatory protein PHO4

1

0

High-throughput

0.279

Low

722029

XPO1
Exportin-1

1

0

High-throughput

0.279

Low

815821

BEM2
GTPase-activating protein BEM2/IPL2

1

0

High-throughput

0.279

Low

843259

AP1M1
AP-1 complex subunit mu-1-I

1

0

High-throughput

0.279

Low

843269

MUS81
Crossover junction endonuclease MUS81

1

0

High-throughput

0.279

Low

843276

MAG2
E3 ubiquitin-protein ligase MAG2

1

0

High-throughput

0.279

Low

843283

DIA2
Protein DIA2

1

0

High-throughput

0.279

Low

656978

BUR1
Serine/threonine-protein kinase BUR1

1

0

High-throughput

0.269

Low

843284

ESA1
Histone acetyltransferase ESA1

1

0

Small-scale

0.261

Low

843268

SPC19
DASH complex subunit SPC19

1

0

High-throughput

0.251

Low

383757

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

436446

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

0

High-throughput

0.249

Low

477577

MYO1
Myosin-1

1

0

Small-scale

0.249

Low

503103

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

679803

CDC48
Cell division control protein 48

1

0

High-throughput

0.249

Low

707399

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

709823

BMH1
Protein BMH1

1

0

High-throughput

0.249

Low

735030

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.249

Low

737888

HOG1
Mitogen-activated protein kinase HOG1

1

0

High-throughput

0.249

Low

747909

SMY2
Protein SMY2

1

0

High-throughput

0.249

Low

778384

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.249

Low

812404

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

843246

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

843249

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.249

Low

843256

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.249

Low

843261

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

843267

BUL2
Ubiquitin ligase-binding protein BUL2

1

0

Small-scale

0.249

Low

843271

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.249

Low

843275

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

843280

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

843282

SGO1
Shugoshin

1

0

High-throughput

0.249

Low

843286

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.249

Low

394662

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.232

Low

592325

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.232

Low

752393

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low

798057

CLPX
ATP-dependent clpX-like chaperone, mitochondrial

1

0

High-throughput

0.232

Low

836749

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.232

Low

843245

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025