Protein: HSK3
DASH complex subunit HSK3 (Helper of ASK1 protein 3) (Outer kinetochore protein HSK3)

Gene: HSK3
Organism: Saccharomyces cerevisiae S288C
Interactions: 62
UniProt ID: P69852

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005874 - microtubule
GO:0008608 - attachment of spindle microtubules to kinetochore
GO:0031116 - positive regulation of microtubule polymerization
GO:0042729 - DASH complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

782591

DAD2
DASH complex subunit DAD2

6

0

Small-scale

0.884

High

999590

SPC19
DASH complex subunit SPC19

6

0

Small-scale

0.884

High

776706

ASK1
DASH complex subunit ASK1

6

0

Small-scale

0.876

High

999578

DAD4
DASH complex subunit DAD4

5

0

Small-scale

0.860

High

917910

DUO1
DASH complex subunit DUO1

4

0

Small-scale

0.838

High

781914

SPC34
DASH complex subunit SPC34

10

0

Small-scale

0.719

High

919100

DAM1
DASH complex subunit DAM1

5

0

Small-scale

0.667

High

826739

DSN1
Kinetochore-associated protein DSN1

4

0

Small-scale

0.643

High

999600

DAD1
DASH complex subunit DAD1

4

0

Small-scale

0.631

High

999571

DAD3
DASH complex subunit DAD3

3

0

Small-scale

0.622

High

753128

NIP80
Protein NIP100

2

1

High-throughput

0.584

High

797902

CENPU
Inner kinetochore subunit AME1

2

0

High-throughput

0.576

High

824865

NDC80
Kinetochore protein NDC80

2

0

Small-scale

0.552

High

999588

CENPP
Inner kinetochore subunit CTF19

1

0

High-throughput

0.493

High

664333

SSD1
Protein SSD1

1

0

High-throughput

0.460

High

665844

KPC1
Protein kinase C-like 1

1

0

High-throughput

0.460

High

672442

STE50
Protein STE50

1

0

High-throughput

0.460

High

678843

AHC2
ADA histone acetyltransferase complex component 2

1

0

High-throughput

0.460

High

735654

SMY1
Kinesin-related protein SMY1

1

0

High-throughput

0.460

High

750752

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.460

High

779788

DYHC
Dynein heavy chain, cytoplasmic

1

0

High-throughput

0.460

High

797347

INCE
Inner centromere protein SLI15

1

0

High-throughput

0.460

High

806048

KEL1
Kelch repeat-containing protein 1

1

0

High-throughput

0.460

High

815045

SNF7
Vacuolar-sorting protein SNF7

1

0

High-throughput

0.460

High

849833

BUD27
Bud site selection protein 27

1

0

High-throughput

0.460

High

866276

HMS2
Probable transcription factor HMS2

1

0

High-throughput

0.460

High

873829

BUL1
Ubiquitin ligase-binding protein BUL1

1

0

High-throughput

0.460

High

915007

ALAT2
Inactive alanine aminotransferase

1

0

High-throughput

0.460

High

917727

KNL1
Outer kinetochore KNL1 complex subunit SPC105

1

0

High-throughput

0.460

High

999586

SEN1
Helicase SEN1

1

0

High-throughput

0.460

High

999592

ATG17
Autophagy-related protein 17

1

0

High-throughput

0.460

High

999593

SP382
Pre-mRNA-splicing factor SPP382

1

0

High-throughput

0.460

High

999597

MFG1
Morphogenetic regulator of filamentous growth protein 1

1

0

High-throughput

0.460

High

548231

BIK1
Nuclear fusion protein BIK1

1

1

Small-scale

0.445

High

816972

BIM1
Protein BIM1

1

0

Small-scale

0.426

High

999598

YL031
Putative uncharacterized protein YLR031W

2

0

High-throughput

0.304

High

677765

STP22
Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease

1

0

High-throughput

0.251

Low

737020

CDC3
Cell division control protein 3

1

0

High-throughput

0.251

Low

749711

TYE7
Transcription factor TYE7

1

0

High-throughput

0.251

Low

777095

BDF1
Bromodomain-containing factor 1

1

0

High-throughput

0.251

Low

797716

MED8
Mediator of RNA polymerase II transcription subunit 8

1

0

High-throughput

0.251

Low

804910

LAM4
Membrane-anchored lipid-binding protein LAM4

1

0

High-throughput

0.251

Low

817749

TSC11
Target of rapamycin complex 2 subunit TSC11

1

0

High-throughput

0.251

Low

818330

LCP5
U3 small nucleolar ribonucleoprotein protein LCP5

1

0

High-throughput

0.251

Low

823221

MED3
Mediator of RNA polymerase II transcription subunit 3

1

0

High-throughput

0.251

Low

824661

BNR1
BNI1-related protein 1

1

0

High-throughput

0.251

Low

844481

GZF3
Protein GZF3

1

0

High-throughput

0.251

Low

850306

FAR7
Factor arrest protein 7

1

0

High-throughput

0.251

Low

850669

KEG1
Beta-1,6-glucan synthesis-associated protein KEG1

1

0

High-throughput

0.251

Low

858452

TAF1
Transcription initiation factor TFIID subunit 1

1

0

High-throughput

0.251

Low

864575

YJE9
Uncharacterized protein YJL049W

1

0

High-throughput

0.251

Low

871017

SNAPN
Biogenesis of lysosome-related organelles complex 1 subunit SNN1

1

0

High-throughput

0.251

Low

917788

MPS2
Monopolar spindle protein 2

1

0

High-throughput

0.251

Low

918756

NNF2
Protein NNF2

1

0

High-throughput

0.251

Low

999587

CIK1
Spindle pole body-associated protein CIK1

1

0

High-throughput

0.251

Low

999589

RT17
Small ribosomal subunit protein uS17m

1

0

High-throughput

0.251

Low

999591

HOB2
Protein YPR117W

1

0

High-throughput

0.251

Low

999594

HDA2
HDA1 complex subunit 2

1

0

High-throughput

0.251

Low

999595

BFR2
Protein BFR2

1

0

High-throughput

0.251

Low

999596

IRC3
Putative ATP-dependent helicase IRC3

1

0

High-throughput

0.251

Low

999599

YP216
Putative ISWI chromatin-remodeling complex subunit YPL216W

1

0

High-throughput

0.251

Low

999601

ERP3
Protein ERP3

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025