HitPredict

Interactor 1: CATG (P08311)
Cathepsin G (CG) (EC 3.4.21.20) [Cleaved into: Cathepsin G, C-terminal truncated form]
Gene: CTSG

Interactor 2: SPB4 (P48594)
Serpin B4 (Leupin) (Peptidase inhibitor 11) (PI-11) (Squamous cell carcinoma antigen 2) (SCCA-2)
Gene: SERPINB4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	12949073
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Serpin~Trypsin
Common GO terms	GO:0005615 - extracellular space GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 255 Hs			1 390
+	Hs
		457955 TRY1_HUMAN (1-246): 8.87e-119: 340: 35.18		SPB8_HUMAN (1-390): 4.87e-152: 435: 44.64
+	Hs
		518736 GRAB_HUMAN (1-245): 7.26e-100: 293: 56.68		SPB9_HUMAN (1-390): 2.63e-166: 472: 45.15
+	Hs
		762249 TRY3_HUMAN (8-246): 9.38e-112: 325: 32.92		SPB12_HUMAN (1-390): 2.98e-146: 422: 47.29
+	Hs
		767104 KLK13_HUMAN (1-252): 1.22e-102: 301: 33.33		SPB6_HUMAN (1-390): 3.61e-156: 446: 45.27
+	Mm
		1221626 KLK8_MOUSE (1-244): 2.53e-98: 289: 33.20		SPB6_MOUSE (1-390): 9.62e-159: 452: 45.39
+	Hs
		628392 KLK2_HUMAN (1-245): 4.73e-98: 288: 30.57		SPB6_HUMAN (1-390): 3.61e-156: 446: 45.27
+	Mm
		459955 Q9Z1R9_MOUSE (1-245): 2.46e-116: 334: 34.13		A1AT1_MOUSE (4-390): 4.86e-136: 396: 31.88
+	Hs
		398000 KLKB1_HUMAN (10-254): 1.8e-103: 315: 27.13		IPSP_HUMAN (6-390): 1.3e-137: 400: 30.83
+	Hs
		369520 KLK13_HUMAN (1-252): 1.22e-102: 301: 33.33		AACT_HUMAN (4-390): 1.3e-141: 411: 33.08
+	Hs
		369428 CATG_HUMAN (1-255): 1.1e-102: 300: 100.00		AACT_HUMAN (4-390): 1.3e-141: 411: 33.08
+	Hs
		369301 CATG_HUMAN (1-255): 1.1e-102: 300: 100.00		A1AT_HUMAN (2-390): 1.45e-139: 405: 32.82
+	Hs
		369234 KLK1_HUMAN (1-246): 1.63e-97: 287: 31.84		ANT3_HUMAN (4-390): 1.68e-142: 415: 38.42
+	Hs
		369437 KLK2_HUMAN (1-245): 4.73e-98: 288: 30.57		AACT_HUMAN (4-390): 1.3e-141: 411: 33.08
+	Hs
		397992 FA11_HUMAN (13-244): 1.19e-97: 299: 28.57		IPSP_HUMAN (6-390): 1.3e-137: 400: 30.83
+	Hs
		369296 KLK1_HUMAN (1-246): 1.63e-97: 287: 31.84		A1AT_HUMAN (2-390): 1.45e-139: 405: 32.82
+	Hs
		425167 KLK2_HUMAN (1-245): 4.73e-98: 288: 30.57		IPSP_HUMAN (6-390): 1.3e-137: 400: 30.83
+	Hs
		664032 PRTN3_HUMAN (20-243): 1.74e-41: 144: 37.50		ILEU_HUMAN (1-390): 1.08e-151: 435: 46.72
+	Hs
		369240 GRAA_HUMAN (20-243): 5.93e-43: 148: 38.24		ANT3_HUMAN (4-390): 1.68e-142: 415: 38.42
+	Hs
		369312 PRTN3_HUMAN (20-243): 1.74e-41: 144: 37.50		A1AT_HUMAN (2-390): 1.45e-139: 405: 32.82
+	Hs
		369417 KLK4_HUMAN (4-244): 9.41e-37: 132: 32.11		A1AT_HUMAN (2-390): 1.45e-139: 405: 32.82