Protein: RPC6
DNA-directed RNA polymerase III subunit RPC6 (RNA polymerase III subunit C6) (DNA-directed RNA polymerase III subunit F) (RNA polymerase III 39 kDa subunit) (RPC39)

Gene: RPC6, POLR3F
Organism: Homo sapiens
Interactions: 67
UniProt ID: Q9H1D9

Gene Ontology (top 5):
GO:0003690 - double-stranded DNA binding
GO:0003899 - DNA-directed RNA polymerase activity
GO:0005654 - nucleoplasm
GO:0005666 - RNA polymerase III complex
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1413119

RPC7L
DNA-directed RNA polymerase III subunit RPC7-like

5

2

Small-scale

0.930

High

1431036

RPC5
DNA-directed RNA polymerase III subunit RPC5

5

1

High-throughput

0.930

High

1429444

MAF1
Repressor of RNA polymerase III transcription MAF1 homolog

4

1

High-throughput

0.903

High

1414272

RPC3
DNA-directed RNA polymerase III subunit RPC3

4

1

Small-scale

0.890

High

186382

RPC7
DNA-directed RNA polymerase III subunit RPC7

3

2

Small-scale

0.861

High

1431037

RPC2
DNA-directed RNA polymerase III subunit RPC2

2

2

Small-scale

0.776

High

430645

RPC4
DNA-directed RNA polymerase III subunit RPC4

6

1

Small-scale

0.735

High

165089

RPC1
DNA-directed RNA polymerase III subunit RPC1

1

1

High-throughput

0.691

High

1371356

TF3B
Transcription factor IIIB 90 kDa subunit

1

4

High-throughput

0.691

High

180391

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

3

1

High-throughput

0.675

High

621963

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

3

1

High-throughput

0.675

High

959053

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

3

1

High-throughput

0.675

High

983702

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

3

1

High-throughput

0.662

High

1431042

RPC10
DNA-directed RNA polymerase III subunit RPC10

3

1

High-throughput

0.662

High

298271

BODG
Gamma-butyrobetaine dioxygenase

3

0

High-throughput

0.638

High

911100

IMA1
Importin subunit alpha-1

3

0

High-throughput

0.634

High

1431043

RPC8
DNA-directed RNA polymerase III subunit RPC8

2

1

High-throughput

0.628

High

628840

TBP
TATA-box-binding protein

2

1

Small-scale

0.619

High

1328069

ATPF2
ATP synthase mitochondrial F1 complex assembly factor 2

2

0

High-throughput

0.580

High

1109213

PRP4K
Serine/threonine-protein kinase PRP4 homolog

1

0

High-throughput

0.558

High

516866

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

2

1

High-throughput

0.552

High

1347864

RIN3
Ras and Rab interactor 3

2

0

High-throughput

0.551

High

64439

BDP1
Transcription factor TFIIIB component B'' homolog

1

1

High-throughput

0.536

High

287475

RPC9
DNA-directed RNA polymerase III subunit RPC9

1

1

High-throughput

0.536

High

761869

HSP74
Heat shock 70 kDa protein 4

1

2

High-throughput

0.536

High

912121

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

1

High-throughput

0.536

High

923535

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

1

High-throughput

0.536

High

952469

UB2G2
Ubiquitin-conjugating enzyme E2 G2

1

0

High-throughput

0.518

High

1371283

KAT5
Histone acetyltransferase KAT5

1

0

High-throughput

0.518

High

832123

IF2G
Eukaryotic translation initiation factor 2 subunit 3

1

1

High-throughput

0.515

High

704554

RXRB
Retinoic acid receptor RXR-beta

1

0

High-throughput

0.513

High

856913

BAG6
Large proline-rich protein BAG6

1

0

High-throughput

0.513

High

1326083

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.513

High

1340665

NEDD1
Protein NEDD1

1

0

High-throughput

0.513

High

1162041

H31T
Histone H3.1t

1

0

High-throughput

0.493

High

415855

HSPB1
Heat shock protein beta-1

1

0

High-throughput

0.493

High

931104

HSP72
Heat shock-related 70 kDa protein 2

1

0

High-throughput

0.493

High

954608

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.493

High

419199

H2A1B
Histone H2A type 1-B/E

1

2

High-throughput

0.489

High

1431035

SUV92
Histone-lysine N-methyltransferase SUV39H2

1

0

High-throughput

0.486

High

1431040

TF3C4
General transcription factor 3C polypeptide 4

1

0

Small-scale

0.480

High

1054787

SUH
Recombining binding protein suppressor of hairless

1

1

High-throughput

0.479

High

1212459

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.460

High

260440

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

607099

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

1114268

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1314414

SLX4
Structure-specific endonuclease subunit SLX4

1

0

High-throughput

0.458

High

1431039

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1217194

RIF1
Telomere-associated protein RIF1

1

0

High-throughput

0.438

High

132924

S28A1
Sodium/nucleoside cotransporter 1

1

0

High-throughput

0.426

High

516803

RPC22
Protein POLR1D, isoform 2

1

0

High-throughput

0.426

High

1064026

ECHP
Peroxisomal bifunctional enzyme

1

0

High-throughput

0.426

High

1224905

TENS2
Tensin-2

2

0

High-throughput

0.300

High

1085969

PNRC1
Proline-rich nuclear receptor coactivator 1

1

0

Small-scale

0.288

High

302266

STC2
Stanniocalcin-2

1

0

High-throughput

0.282

High

1390769

WDR89
WD repeat-containing protein 89

1

0

High-throughput

0.282

High

1431041

ERG28
Ergosterol biosynthetic protein 28 homolog

1

0

High-throughput

0.282

High

1275498

TRM1L
tRNA

1

0

High-throughput

0.279

Low

1337801

DP13B
DCC-interacting protein 13-beta

1

0

High-throughput

0.279

Low

1431038

UVRAG
UV radiation resistance-associated gene protein

1

0

High-throughput

0.279

Low

47415

A0A6Q8PF08
Peripheral myelin protein 22

1

0

High-throughput

0.268

Low

246134

KIF1B
Kinesin-like protein KIF1B

1

0

High-throughput

0.268

Low

301692

WFS1
Wolframin

1

0

High-throughput

0.268

Low

705551

GRN
Progranulin

1

0

High-throughput

0.268

Low

1081564

Q0VDC6
peptidylprolyl isomerase

1

0

High-throughput

0.268

Low

1369631

APBB2
Amyloid beta precursor protein binding family B member 2

1

0

High-throughput

0.268

Low

1276771

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025