Protein: SELS
Selenoprotein S (SelS) (VCP-interacting membrane protein)

Gene: SELS, SELENOS
Organism: Homo sapiens
Interactions: 63
UniProt ID: Q9BQE4

Gene Ontology (top 5):
GO:0002865 - negative regulation of acute inflammatory response to antigenic stimulus
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0005881 - cytoplasmic microtubule
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

935064

TERA
Transitional endoplasmic reticulum ATPase

14

0

Small-scale

0.933

High

1410653

DERL1
Derlin-1

8

1

Small-scale

0.748

High

1410656

DERL2
Derlin-2

3

1

Small-scale

0.656

High

1410666

SELK
Selenoprotein K

2

0

Small-scale

0.585

High

1058621

CKAP4
Cytoskeleton-associated protein 4

2

1

Small-scale

0.584

High

1287422

SYVN1
E3 ubiquitin-protein ligase synoviolin

2

1

Small-scale

0.584

High

1410663

AMFR
E3 ubiquitin-protein ligase AMFR

2

1

Small-scale

0.584

High

1246211

APOA5
Apolipoprotein A-V

2

0

High-throughput

0.580

High

564287

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

Small-scale

0.537

High

789561

PPARG
Peroxisome proliferator-activated receptor gamma

1

0

Small-scale

0.537

High

1134355

IMB1
Importin subunit beta-1

1

0

Small-scale

0.537

High

122640

UBXN8
UBX domain-containing protein 8

1

1

High-throughput

0.536

High

1386339

FAF2
FAS-associated factor 2

1

1

High-throughput

0.536

High

1410665

MFHA1
Malignant fibrous histiocytoma-amplified sequence 1

1

0

High-throughput

0.513

High

403213

APOB
Apolipoprotein B-100

1

0

Small-scale

0.513

High

771812

SCN4A
Sodium channel protein type 4 subunit alpha

1

0

High-throughput

0.513

High

1121143

UBE4A
Ubiquitin conjugation factor E4 A

1

0

High-throughput

0.513

High

515900

SAA1
Serum amyloid A-1 protein

1

0

Small-scale

0.480

High

374164

RASN
GTPase NRas

1

1

High-throughput

0.479

High

375887

RASK
GTPase KRas

1

1

High-throughput

0.479

High

1383032

LRC59
Leucine-rich repeat-containing protein 59

1

1

High-throughput

0.479

High

1408191

RNF5
E3 ubiquitin-protein ligase RNF5

1

1

Small-scale

0.479

High

48251

TM129
E3 ubiquitin-protein ligase TM129

1

0

Small-scale

0.458

High

174068

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

0

High-throughput

0.458

High

770784

PGH2
Prostaglandin G/H synthase 2

1

0

Small-scale

0.458

High

951382

SC61B
Protein transport protein Sec61 subunit beta

1

0

High-throughput

0.458

High

1041248

CAV1
Caveolin-1

1

0

Small-scale

0.458

High

1136679

HERP1
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein

1

0

Small-scale

0.458

High

1340057

SVIP
Small VCP/p97-interacting protein

1

0

Small-scale

0.458

High

1347641

NPL4
Nuclear protein localization protein 4 homolog

1

0

Small-scale

0.458

High

1365497

EDEM1
ER degradation-enhancing alpha-mannosidase-like protein 1

1

0

Small-scale

0.458

High

1369983

UFD1
Ubiquitin recognition factor in ER-associated degradation protein 1

1

0

Small-scale

0.458

High

1404173

SEC62
Translocation protein SEC62

1

0

High-throughput

0.458

High

1410655

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.458

High

1410657

TMT1A
Thiol S-methyltransferase TMT1A

1

0

High-throughput

0.458

High

1410660

SNTG2
Gamma-2-syntrophin

1

0

Small-scale

0.458

High

166400

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

1

2

High-throughput

0.445

High

613444

VINC
Vinculin

1

1

High-throughput

0.445

High

1251180

ZNT10
Calcium/manganese antiporter SLC30A10

1

2

High-throughput

0.445

High

1141893

EEA1
Early endosome antigen 1

1

1

High-throughput

0.437

High

256127

S19A2
Thiamine transporter 1

1

0

High-throughput

0.426

High

1093569

TRDN
Triadin

1

0

High-throughput

0.426

High

1410654

S12A9
Solute carrier family 12 member 9

1

0

High-throughput

0.426

High

1337927

ZNT7
Zinc transporter 7

1

2

High-throughput

0.407

High

1410664

KLDC2
Kelch domain-containing protein 2

5

0

Small-scale

0.375

High

1389569

SAAL1
Protein SAAL1

2

0

High-throughput

0.313

High

1006657

SRPK2
SRSF protein kinase 2

1

0

High-throughput

0.287

High

1023608

CYC
Cytochrome c

1

0

High-throughput

0.279

Low

1392158

RUSF1
RUS family member 1

1

0

High-throughput

0.279

Low

1410662

GT2D1
General transcription factor II-I repeat domain-containing protein 1

1

0

Small-scale

0.251

Low

207974

TET3
Methylcytosine dioxygenase TET3

1

0

High-throughput

0.249

Low

294246

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

761851

HSP74
Heat shock 70 kDa protein 4

1

0

Small-scale

0.249

Low

773263

MYH10
Myosin-10

1

0

High-throughput

0.249

Low

937877

FOXA1
Hepatocyte nuclear factor 3-alpha

1

0

High-throughput

0.249

Low

1005027

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

1135790

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

High-throughput

0.249

Low

1238108

HMBX1
Homeobox-containing protein 1

1

0

High-throughput

0.249

Low

1280449

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

0

High-throughput

0.249

Low

1410658

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.249

Low

1410659

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.249

Low

848819

MAGAA
Melanoma-associated antigen 10

1

0

High-throughput

0.232

Low

1410661

TMEM9
Proton-transporting V-type ATPase complex assembly regulator TMEM9

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025