Protein: LTOR2
Ragulator complex protein LAMTOR2 (Endosomal adaptor protein p14) (Late endosomal/lysosomal Mp1-interacting protein) (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 2) (Mitogen-activated protein-binding protein-interacting protein) (MAPBP-interacting protein) (Roadblock domain-containing protein 3)

Gene: LTOR2, LAMTOR2
Organism: Homo sapiens
Interactions: 73
UniProt ID: Q9Y2Q5

Gene Ontology (top 5):
GO:0001558 - regulation of cell growth
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005765 - lysosomal membrane
GO:0005770 - late endosome
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1459734

LTOR3
Ragulator complex protein LAMTOR3

15

2

Small-scale

0.987

High

219250

LTOR5
Ragulator complex protein LAMTOR5

6

0

Small-scale

0.902

High

1272167

RRAGA
Ras-related GTP-binding protein A

6

3

Small-scale

0.735

High

1438006

RRAGC
Ras-related GTP-binding protein C

6

3

Small-scale

0.735

High

1233595

LTOR1
Ragulator complex protein LAMTOR1

9

0

Small-scale

0.722

High

1219792

RRAGB
Ras-related GTP-binding protein B

5

3

Small-scale

0.720

High

1450647

ARL8B
ADP-ribosylation factor-like protein 8B

1

2

High-throughput

0.691

High

1081835

LTOR4
Ragulator complex protein LAMTOR4

5

0

Small-scale

0.688

High

1334295

S38A9
Neutral amino acid transporter 9

5

0

Small-scale

0.684

High

1447135

RRAGD
Ras-related GTP-binding protein D

3

3

Small-scale

0.662

High

901692

RAB7A
Ras-related protein Rab-7a

2

1

High-throughput

0.611

High

961584

VA0D1
V-type proton ATPase subunit d 1

2

0

Small-scale

0.602

High

540769

LAMP1
Lysosome-associated membrane glycoprotein 1

2

0

Small-scale

0.592

High

1314570

TM192
Transmembrane protein 192

2

0

High-throughput

0.585

High

641709

ERBB3
Receptor tyrosine-protein kinase erbB-3

2

0

High-throughput

0.551

High

839412

MTOR
Serine/threonine-protein kinase mTOR

2

0

Small-scale

0.547

High

1322680

RPTOR
Regulatory-associated protein of mTOR

2

0

Small-scale

0.547

High

956551

RAB2A
Ras-related protein Rab-2A

1

1

High-throughput

0.536

High

958054

RAB14
Ras-related protein Rab-14

1

1

High-throughput

0.536

High

292783

RENR
Renin receptor

1

0

High-throughput

0.513

High

463267

YES
Tyrosine-protein kinase Yes

1

0

High-throughput

0.513

High

637076

VATB2
V-type proton ATPase subunit B, brain isoform

1

0

Small-scale

0.513

High

1008499

BL1S1
Biogenesis of lysosome-related organelles complex 1 subunit 1

1

0

High-throughput

0.513

High

1154788

VAMP3
Vesicle-associated membrane protein 3

1

0

High-throughput

0.513

High

1286727

PP4P1
Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

1

0

High-throughput

0.513

High

1371993

VPP1
V-type proton ATPase 116 kDa subunit a 1

1

0

High-throughput

0.513

High

1380387

BORC5
BLOC-1-related complex subunit 5

1

0

High-throughput

0.513

High

1490863

PKHM1
Pleckstrin homology domain-containing family M member 1

1

0

Small-scale

0.513

High

1490864

KC1G3
Casein kinase I isoform gamma-3

1

0

High-throughput

0.513

High

718667

CDC27
Cell division cycle protein 27 homolog

1

2

High-throughput

0.489

High

1093092

CDC16
Cell division cycle protein 16 homolog

1

2

High-throughput

0.489

High

1408498

VRK1
Serine/threonine-protein kinase VRK1

1

1

High-throughput

0.489

High

1460734

CDC23
Cell division cycle protein 23 homolog

1

2

High-throughput

0.489

High

466532

RHOC
Rho-related GTP-binding protein RhoC

1

4

High-throughput

0.479

High

560563

IFM1
Interferon-induced transmembrane protein 1

1

1

High-throughput

0.479

High

581381

RAC2
Ras-related C3 botulinum toxin substrate 2

1

5

High-throughput

0.479

High

601510

RHOQ
Rho-related GTP-binding protein RhoQ

1

5

High-throughput

0.479

High

902153

RAB9A
Ras-related protein Rab-9A

1

1

High-throughput

0.479

High

955771

CDC42
Cell division control protein 42 homolog

1

5

High-throughput

0.479

High

962651

RHOA
Transforming protein RhoA

1

4

High-throughput

0.479

High

1015919

RHOG
Rho-related GTP-binding protein RhoG

1

5

High-throughput

0.479

High

1031610

IFM3
Interferon-induced transmembrane protein 3

1

1

High-throughput

0.479

High

178446

NPC1
NPC intracellular cholesterol transporter 1

1

0

High-throughput

0.458

High

637118

VATC1
V-type proton ATPase subunit C 1

1

0

High-throughput

0.458

High

693144

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.458

High

947320

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

0

High-throughput

0.458

High

1038381

MP2K1
Dual specificity mitogen-activated protein kinase kinase 1

1

0

Small-scale

0.458

High

1091853

TP4A2
Protein tyrosine phosphatase type IVA 2

1

0

Small-scale

0.458

High

1450377

S38A7
Sodium-coupled neutral amino acid transporter 7

1

0

Small-scale

0.458

High

538719

GTR1
Solute carrier family 2, facilitated glucose transporter member 1

1

0

High-throughput

0.426

High

835026

S19A1
Reduced folate transporter

1

0

High-throughput

0.426

High

1238908

MFS12
Major facilitator superfamily domain-containing protein 12

1

0

High-throughput

0.426

High

1392371

BORC6
BLOC-1-related complex subunit 6

5

0

High-throughput

0.374

High

165675

SCAM3
Secretory carrier-associated membrane protein 3

1

0

High-throughput

0.279

Low

391675

FRIH
Ferritin heavy chain

1

0

High-throughput

0.279

Low

630098

BTF3
Transcription factor BTF3

1

0

High-throughput

0.279

Low

1055874

RING1
E3 ubiquitin-protein ligase RING1

1

0

High-throughput

0.279

Low

1238064

S18B1
MFS-type transporter SLC18B1

1

0

High-throughput

0.279

Low

1246516

BL1S2
Biogenesis of lysosome-related organelles complex 1 subunit 2

1

0

High-throughput

0.279

Low

1294867

STX12
Syntaxin-12

1

0

High-throughput

0.279

Low

1338688

T185A
Transmembrane protein 185A

1

0

High-throughput

0.279

Low

1356801

STYX
Serine/threonine/tyrosine-interacting protein

1

0

High-throughput

0.279

Low

1384080

BORC7
BLOC-1-related complex subunit 7

1

0

High-throughput

0.279

Low

1419524

NSD3
Histone-lysine N-methyltransferase NSD3

1

0

High-throughput

0.279

Low

1447469

ANLN
Anillin

1

0

High-throughput

0.279

Low

1450369

T184C
Transmembrane protein 184C

1

0

High-throughput

0.279

Low

1460632

TBD
Tubulin delta chain

1

0

High-throughput

0.279

Low

294554

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

1277974

NUFP2
FMR1-interacting protein NUFIP2

1

0

Small-scale

0.249

Low

1367637

ESR2
Estrogen receptor beta

1

0

High-throughput

0.249

Low

341224

VATG2
V-type proton ATPase subunit G 2

1

0

High-throughput

0.232

Low

352740

NUDT3
Diphosphoinositol polyphosphate phosphohydrolase 1

1

0

High-throughput

0.232

Low

423861

APOD
Apolipoprotein D

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025