Protein: ATP5E
ATP synthase F(1) complex subunit epsilon, mitochondrial (ATPase subunit epsilon) (ATP synthase F1 subunit epsilon)

Gene: ATP5E, ATP5F1E
Organism: Homo sapiens
Interactions: 56
UniProt ID: P56381

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005759 - mitochondrial matrix
GO:0015986 - proton motive force-driven ATP synthesis
GO:0016787 - hydrolase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

716664

ATPD
ATP synthase F(1) complex subunit delta, mitochondrial

10

1

High-throughput

0.973

High

784561

ATPG
ATP synthase F(1) complex subunit gamma, mitochondrial

8

1

High-throughput

0.960

High

680293

ATPA
ATP synthase F(1) complex subunit alpha, mitochondrial

4

1

High-throughput

0.676

High

940634

ATIF1
ATPase inhibitor, mitochondrial

2

1

High-throughput

0.584

High

905728

CAV2
Caveolin-2

2

1

High-throughput

0.521

High

940613

S36A1
Proton-coupled amino acid transporter 1

1

1

High-throughput

0.489

High

940620

S38A2
Sodium-coupled neutral amino acid symporter 2

1

5

High-throughput

0.489

High

940627

S38A1
Sodium-coupled neutral amino acid symporter 1

1

5

High-throughput

0.489

High

50854

NDUF8
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 8

1

0

High-throughput

0.458

High

137690

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

0

High-throughput

0.458

High

143820

NDKM
Nucleoside diphosphate kinase, mitochondrial

1

0

High-throughput

0.458

High

275000

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

0

High-throughput

0.458

High

348443

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

0

High-throughput

0.458

High

350826

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

0

High-throughput

0.458

High

505425

CISD3
CDGSH iron-sulfur domain-containing protein 3, mitochondrial

1

0

High-throughput

0.458

High

940602

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

940609

NDUF5
Arginine-hydroxylase NDUFAF5, mitochondrial

1

0

High-throughput

0.458

High

940612

MIC27
MICOS complex subunit MIC27

1

0

High-throughput

0.458

High

940614

PTPM1
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

1

0

High-throughput

0.458

High

940615

COQ8B
Atypical kinase COQ8B, mitochondrial

1

0

High-throughput

0.458

High

940617

COQ2
4-hydroxybenzoate polyprenyltransferase, mitochondrial

1

0

High-throughput

0.458

High

940618

FMC1
Protein FMC1 homolog

1

0

High-throughput

0.458

High

940619

ATPMK
ATP synthase F(0) complex subunit k, mitochondrial

1

0

High-throughput

0.458

High

940621

COQ7
NADPH-dependent 3-demethoxyubiquinone 3-hydroxylase, mitochondrial

1

0

High-throughput

0.458

High

940622

DHRS4
Dehydrogenase/reductase SDR family member 4

1

0

High-throughput

0.458

High

940623

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

0

High-throughput

0.458

High

940624

SCOT2
Succinyl-CoA:3-ketoacid coenzyme A transferase 2, mitochondrial

1

0

High-throughput

0.458

High

940625

NMES1
Normal mucosa of esophagus-specific gene 1 protein

1

0

High-throughput

0.458

High

940629

MCCB
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial

1

0

High-throughput

0.458

High

940630

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.458

High

940631

NDUF4
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4

1

0

High-throughput

0.458

High

940632

MRES1
Mitochondrial transcription rescue factor 1

1

0

High-throughput

0.458

High

940635

COQ6
Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial

1

0

High-throughput

0.458

High

133473

ACATN
Acetyl-coenzyme A transporter 1

1

1

High-throughput

0.437

High

940603

CTSL2
CTD small phosphatase-like protein 2

1

1

High-throughput

0.437

High

940608

TM63B
Mechanosensitive cation channel TMEM63B

1

1

High-throughput

0.437

High

940610

ATLA3
Atlastin-3

1

1

High-throughput

0.437

High

940606

S35G1
Solute carrier family 35 member G1

1

1

High-throughput

0.407

High

940607

S35F1
Solute carrier family 35 member F1

1

1

High-throughput

0.407

High

940611

ATRAP
Type-1 angiotensin II receptor-associated protein

2

0

High-throughput

0.316

High

423963

CP17A
Steroid 17-alpha-hydroxylase/17,20 lyase

1

0

High-throughput

0.282

High

279134

ULK1
Serine/threonine-protein kinase ULK1

1

0

High-throughput

0.279

Low

902815

BLK
Tyrosine-protein kinase Blk

1

0

High-throughput

0.279

Low

940604

P2RY6
P2Y purinoceptor 6

1

0

High-throughput

0.279

Low

940626

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.279

Low

940628

SG196
Protein O-mannose kinase

1

0

High-throughput

0.279

Low

922298

LIMK2
LIM domain kinase 2

1

0

High-throughput

0.269

Low

290902

PPM1B
Protein phosphatase 1B

1

0

High-throughput

0.249

Low

536842

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.249

Low

695057

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

718999

WEE1
Wee1-like protein kinase

1

0

High-throughput

0.249

Low

940601

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

0

High-throughput

0.249

Low

940616

DDX27
Probable ATP-dependent RNA helicase DDX27

1

0

High-throughput

0.249

Low

940633

TES
Testin

1

0

High-throughput

0.249

Low

256014

S19A2
Thiamine transporter 1

1

0

High-throughput

0.232

Low

940605

SC5A9
Sodium/glucose cotransporter 4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025