Protein: NDUF4
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 (Hormone-regulated proliferation-associated protein of 20 kDa)

Gene: NDUF4, NDUFAF4
Organism: Homo sapiens
Interactions: 191
UniProt ID: Q9P032

Gene Ontology (top 5):
GO:0005516 - calmodulin binding
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005829 - cytosol
GO:0031966 - mitochondrial membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1413946

NDUF3
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3

8

0

High-throughput

0.723

High

283999

NDUS3
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

8

0

High-throughput

0.714

High

275409

NDUS7
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial

5

0

High-throughput

0.686

High

1453706

NDUAD
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13

4

0

High-throughput

0.667

High

1410335

ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

4

0

High-throughput

0.661

High

1436122

ACAD9
Complex I assembly factor ACAD9, mitochondrial

4

0

High-throughput

0.653

High

1446591

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

3

0

High-throughput

0.638

High

127583

NDUS8
NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial

3

0

High-throughput

0.622

High

275777

NDUS2
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial

3

0

High-throughput

0.622

High

1162263

NDUA5
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5

3

0

High-throughput

0.622

High

1453713

CIA30
Complex I intermediate-associated protein 30, mitochondrial

3

0

High-throughput

0.622

High

231277

NDUS5
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5

2

0

High-throughput

0.602

High

223662

NDUB5
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial

2

0

High-throughput

0.585

High

1310482

HSC20
Iron-sulfur cluster co-chaperone protein HscB

2

0

High-throughput

0.585

High

282116

MPPB
Mitochondrial-processing peptidase subunit beta

2

1

High-throughput

0.584

High

1083785

MPPA
Mitochondrial-processing peptidase subunit alpha

2

1

High-throughput

0.584

High

279956

CISY
Citrate synthase, mitochondrial

2

0

High-throughput

0.559

High

348779

AIFM1
Apoptosis-inducing factor 1, mitochondrial

2

0

High-throughput

0.559

High

1058334

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

2

0

High-throughput

0.559

High

1087601

GRSF1
G-rich sequence factor 1

2

0

High-throughput

0.559

High

1162599

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

2

0

High-throughput

0.559

High

351980

S1PR4
Sphingosine 1-phosphate receptor 4

1

1

High-throughput

0.536

High

1412769

FEM1A
Protein fem-1 homolog A

1

1

High-throughput

0.536

High

127733

TR10A
Tumor necrosis factor receptor superfamily member 10A

1

0

High-throughput

0.513

High

223764

NDUB3
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3

1

0

High-throughput

0.513

High

281832

NDUB1
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1

1

0

High-throughput

0.513

High

291872

STK16
Serine/threonine-protein kinase 16

1

0

High-throughput

0.513

High

328274

NDUA3
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3

1

0

High-throughput

0.513

High

333603

NDUC2
NADH dehydrogenase [ubiquinone] 1 subunit C2

1

0

High-throughput

0.513

High

397712

NU4M
NADH-ubiquinone oxidoreductase chain 4

1

0

High-throughput

0.513

High

839927

AF9
Protein AF-9

1

0

High-throughput

0.513

High

1161244

MK06
Mitogen-activated protein kinase 6

1

0

High-throughput

0.513

High

1216291

NDUF5
Arginine-hydroxylase NDUFAF5, mitochondrial

1

0

High-throughput

0.513

High

1242648

FAHD1
Oxaloacetate tautomerase FAHD1, mitochondrial

1

0

High-throughput

0.513

High

1308040

T126B
Complex I assembly factor TMEM126B, mitochondrial

1

0

High-throughput

0.513

High

1420169

B2L14
Apoptosis facilitator Bcl-2-like protein 14

1

0

High-throughput

0.513

High

1430989

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.513

High

1435667

WDR26
WD repeat-containing protein 26

1

0

High-throughput

0.513

High

1451403

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

0

High-throughput

0.513

High

301738

WFS1
Wolframin

1

0

High-throughput

0.493

High

166064

FFAR1
Free fatty acid receptor 1

1

2

High-throughput

0.489

High

182813

GP182
G-protein coupled receptor 182

1

2

High-throughput

0.489

High

1142199

P2RY6
P2Y purinoceptor 6

1

2

High-throughput

0.489

High

124658

EYA2
Protein phosphatase EYA2

1

1

High-throughput

0.479

High

287403

RF1M
Peptide chain release factor 1, mitochondrial

1

2

High-throughput

0.479

High

471294

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

1

High-throughput

0.479

High

554850

ODBA
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial

1

1

High-throughput

0.479

High

856413

IF2M
Translation initiation factor IF-2, mitochondrial

1

1

High-throughput

0.479

High

1092677

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

1

High-throughput

0.479

High

1117871

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

1

High-throughput

0.479

High

1135944

FAKD3
FAST kinase domain-containing protein 3, mitochondrial

1

3

High-throughput

0.479

High

1163879

DUS6
Dual specificity protein phosphatase 6

1

1

High-throughput

0.479

High

1206254

PREP
Presequence protease, mitochondrial

1

2

High-throughput

0.479

High

1240351

RUSD3
Mitochondrial mRNA pseudouridine synthase RPUSD3

1

1

High-throughput

0.479

High

1273020

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

3

High-throughput

0.479

High

1337242

MCU
Calcium uniporter protein, mitochondrial

1

1

High-throughput

0.479

High

1340524

DNJB8
DnaJ homolog subfamily B member 8

1

1

High-throughput

0.479

High

1381134

RRF2M
Ribosome-releasing factor 2, mitochondrial

1

1

High-throughput

0.479

High

1381759

FAKD4
FAST kinase domain-containing protein 4

1

3

High-throughput

0.479

High

1383571

MCUR1
Mitochondrial calcium uniporter regulator 1

1

1

High-throughput

0.479

High

1386043

RUSD4
Pseudouridylate synthase RPUSD4, mitochondrial

1

1

High-throughput

0.479

High

1387235

TIM14
Mitochondrial import inner membrane translocase subunit TIM14

1

1

High-throughput

0.479

High

1397184

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

1

2

High-throughput

0.479

High

1397675

IMP1L
Mitochondrial inner membrane protease subunit 1

1

1

High-throughput

0.479

High

1401646

EFGM
Elongation factor G, mitochondrial

1

1

High-throughput

0.479

High

1403459

IMP2L
Mitochondrial inner membrane protease subunit 2

1

1

High-throughput

0.479

High

1428821

CC90B
Coiled-coil domain-containing protein 90B, mitochondrial

1

1

High-throughput

0.479

High

1432642

MTRFR
Mitochondrial translation release factor in rescue

1

2

High-throughput

0.479

High

1451264

MCUB
Calcium uniporter regulatory subunit MCUb, mitochondrial

1

1

High-throughput

0.479

High

1452853

FAKD2
FAST kinase domain-containing protein 2, mitochondrial

1

3

High-throughput

0.479

High

1453708

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

2

High-throughput

0.479

High

1453716

DJC15
DnaJ homolog subfamily C member 15

1

1

High-throughput

0.479

High

61666

VWA8
von Willebrand factor A domain-containing protein 8

1

0

High-throughput

0.458

High

66320

MET15
12S rRNA N(4)-cytidine methyltransferase METTL15

1

0

High-throughput

0.458

High

71772

NUD19
Acyl-coenzyme A diphosphatase NUDT19

1

0

High-throughput

0.458

High

183760

RT12
Small ribosomal subunit protein uS12m

1

0

High-throughput

0.458

High

216839

HTRA2
Serine protease HTRA2, mitochondrial

1

0

High-throughput

0.458

High

243162

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

275122

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

0

High-throughput

0.458

High

317689

ATG12
Ubiquitin-like protein ATG12

1

0

High-throughput

0.458

High

351025

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

0

High-throughput

0.458

High

353995

NDUBA
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10

1

0

High-throughput

0.458

High

361663

OTC
Ornithine transcarbamylase, mitochondrial

1

0

High-throughput

0.458

High

519257

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.458

High

533022

CH60
60 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.458

High

560122

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

1

0

High-throughput

0.458

High

611392

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

0

High-throughput

0.458

High

764453

CTNA1
Catenin alpha-1

1

0

High-throughput

0.458

High

784753

ATPG
ATP synthase F(1) complex subunit gamma, mitochondrial

1

0

High-throughput

0.458

High

786290

LONM
Lon protease homolog, mitochondrial

1

0

High-throughput

0.458

High

828993

MDHM
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

831555

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

842003

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.458

High

852063

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.458

High

882931

EFTU
Elongation factor Tu, mitochondrial

1

0

High-throughput

0.458

High

940631

ATP5E
ATP synthase F(1) complex subunit epsilon, mitochondrial

1

0

High-throughput

0.458

High

959279

ABCE1
ATP-binding cassette sub-family E member 1

1

0

High-throughput

0.458

High

971208

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

975286

ARF6
ADP-ribosylation factor 6

1

0

High-throughput

0.458

High

1015862

RHOG
Rho-related GTP-binding protein RhoG

1

0

High-throughput

0.458

High

1024217

TFAM
Transcription factor A, mitochondrial

1

0

High-throughput

0.458

High

1033797

PO5F1
POU domain, class 5, transcription factor 1

1

0

High-throughput

0.458

High

1048740

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1062854

QOR
Quinone oxidoreductase

1

0

High-throughput

0.458

High

1090576

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

0

High-throughput

0.458

High

1123463

ICT1
Large ribosomal subunit protein mL62

1

0

High-throughput

0.458

High

1149644

SURF1
Surfeit locus protein 1

1

0

High-throughput

0.458

High

1178434

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

1207171

SYAM
Alanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.458

High

1220853

RN123
E3 ubiquitin-protein ligase RNF123

1

0

High-throughput

0.458

High

1234554

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.458

High

1241359

CH082
UPF0598 protein C8orf82

1

0

High-throughput

0.458

High

1270664

COX15
Heme A synthase COX15

1

0

High-throughput

0.458

High

1307941

ARMC8
Armadillo repeat-containing protein 8

1

0

High-throughput

0.458

High

1338407

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

1359201

MAIP1
m-AAA protease-interacting protein 1, mitochondrial

1

0

High-throughput

0.458

High

1366607

AKAP1
A-kinase anchor protein 1, mitochondrial

1

0

High-throughput

0.458

High

1384897

CHCH1
Small ribosomal subunit protein mS37

1

0

High-throughput

0.458

High

1388299

RRFM
Ribosome-recycling factor, mitochondrial

1

0

High-throughput

0.458

High

1388439

MTEF3
Transcription termination factor 3, mitochondrial

1

0

High-throughput

0.458

High

1388604

OMA1
Metalloendopeptidase OMA1, mitochondrial

1

0

High-throughput

0.458

High

1389921

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

0

High-throughput

0.458

High

1394061

COX14
Cytochrome c oxidase assembly protein COX14

1

0

High-throughput

0.458

High

1397501

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

1406075

PHB2
Prohibitin-2

1

0

High-throughput

0.458

High

1412360

TIM29
Mitochondrial import inner membrane translocase subunit Tim29

1

0

High-throughput

0.458

High

1412467

TACO1
Translational activator of cytochrome c oxidase 1

1

0

High-throughput

0.458

High

1412608

CQ080
Mitochondrial nucleoid-associated protein 1

1

0

High-throughput

0.458

High

1413033

MTG1
Mitochondrial ribosome-associated GTPase 1

1

0

High-throughput

0.458

High

1414108

TMM70
Transmembrane protein 70, mitochondrial

1

0

High-throughput

0.458

High

1414683

MIC26
MICOS complex subunit MIC26

1

0

High-throughput

0.458

High

1416572

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

0

High-throughput

0.458

High

1418917

RT26
Small ribosomal subunit protein mS26

1

0

High-throughput

0.458

High

1420430

NMES1
Normal mucosa of esophagus-specific gene 1 protein

1

0

High-throughput

0.458

High

1428395

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

0

High-throughput

0.458

High

1428757

SLIRP
SRA stem-loop-interacting RNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1431220

S2551
Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51

1

0

High-throughput

0.458

High

1431985

IF3M
Translation initiation factor IF-3, mitochondrial

1

0

High-throughput

0.458

High

1432326

PARL
Presenilin-associated rhomboid-like protein, mitochondrial

1

0

High-throughput

0.458

High

1433744

MTG2
Mitochondrial ribosome-associated GTPase 2

1

0

High-throughput

0.458

High

1435384

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1435815

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.458

High

1446269

NGRN
Neugrin

1

0

High-throughput

0.458

High

1450455

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

0

High-throughput

0.458

High

1451351

RMND1
Required for meiotic nuclear division protein 1 homolog

1

0

High-throughput

0.458

High

1451457

AKIP
Small ribosomal subunit protein mS38

1

0

High-throughput

0.458

High

1453705

NDUF4
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4

1

0

High-throughput

0.458

High

1453707

MRES1
Mitochondrial transcription rescue factor 1

1

0

High-throughput

0.458

High

1453709

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1453712

PDIP2
Polymerase delta-interacting protein 2

1

0

High-throughput

0.458

High

1453715

RM11
Large ribosomal subunit protein uL11m

1

0

High-throughput

0.458

High

341692

EYA4
Protein phosphatase EYA4

1

1

High-throughput

0.437

High

1098211

DUS8
Dual specificity protein phosphatase 8

1

1

High-throughput

0.437

High

1448840

TMPS4
Transmembrane protease serine 4

1

1

High-throughput

0.437

High

296638

TNF13
Tumor necrosis factor ligand superfamily member 13

1

0

High-throughput

0.426

High

401614

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.426

High

593619

GDC
Solute carrier family 25 member 16

1

0

High-throughput

0.426

High

653625

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.426

High

1391814

AURKB
Aurora kinase B

1

0

High-throughput

0.426

High

1453711

SYFA
Phenylalanine--tRNA ligase alpha subunit

1

0

High-throughput

0.426

High

437809

HEPS
Serine protease hepsin

1

1

High-throughput

0.407

High

1366279

LPAR1
Lysophosphatidic acid receptor 1

1

1

High-throughput

0.407

High

653779

CRYGS
Gamma-crystallin S

2

0

High-throughput

0.313

High

66906

SPDE4
Speedy protein E4

1

0

High-throughput

0.279

Low

260979

RAMP3
Receptor activity-modifying protein 3

1

0

High-throughput

0.279

Low

469563

SYPH
Synaptophysin

1

0

High-throughput

0.279

Low

957031

CXCR4
C-X-C chemokine receptor type 4

1

0

High-throughput

0.279

Low

1085957

HYAL1
Hyaluronidase-1

1

0

High-throughput

0.279

Low

1147869

DHC24
Delta(24)-sterol reductase

1

0

High-throughput

0.279

Low

1350092

SPP2B
Signal peptide peptidase-like 2B

1

0

High-throughput

0.279

Low

705585

GRN
Progranulin

1

0

High-throughput

0.268

Low

294450

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

406746

MYCN
N-myc proto-oncogene protein

1

0

High-throughput

0.249

Low

589900

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

607170

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.249

Low

696718

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

769376

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

848304

MAGA3
Melanoma-associated antigen 3

1

0

Small-scale

0.249

Low

937946

FOXA1
Hepatocyte nuclear factor 3-alpha

1

0

High-throughput

0.249

Low

1233536

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.249

Low

1415079

LRC61
Leucine-rich repeat-containing protein 61

1

0

High-throughput

0.249

Low

1433458

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

1

0

High-throughput

0.249

Low

1434094

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1450116

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.249

Low

1451707

DJC28
DnaJ homolog subfamily C member 28

1

0

High-throughput

0.249

Low

1453710

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

0

Small-scale

0.249

Low

844977

EAA2
Excitatory amino acid transporter 2

1

0

High-throughput

0.232

Low

1208966

DCA10
DDB1- and CUL4-associated factor 10

1

0

High-throughput

0.232

Low

1235236

LAIR2
Leukocyte-associated immunoglobulin-like receptor 2

1

0

High-throughput

0.232

Low

1453714

TMED5
Transmembrane emp24 domain-containing protein 5

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025