Protein: CHSS2
Chondroitin sulfate synthase 2 (EC 2.4.1.175) (EC 2.4.1.226) (Chondroitin glucuronyltransferase 2) (Chondroitin-polymerizing factor) (ChPF) (Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II) (N-acetylgalactosaminyltransferase 2)

Gene: CHSS2, CHPF
Organism: Homo sapiens
Interactions: 53
UniProt ID: Q8IZ52

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0005759 - mitochondrial matrix
GO:0005829 - cytosol
GO:0032580 - Golgi cisterna membrane
GO:0046872 - metal ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1315951

FBX6
F-box only protein 6

2

1

High-throughput

0.584

High

242246

PRKN
E3 ubiquitin-protein ligase parkin

1

2

Small-scale

0.578

High

962253

RHOA
Transforming protein RhoA

2

1

High-throughput

0.571

High

1116243

PTC1
Protein patched homolog 1

2

3

High-throughput

0.558

High

1197822

S39AC
Zinc transporter ZIP12

2

20

High-throughput

0.549

High

1258450

CHSS3
Chondroitin sulfate synthase 3

1

10

High-throughput

0.536

High

1315957

B3GN3
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3

1

8

High-throughput

0.536

High

1315956

FBW1A
F-box/WD repeat-containing protein 1A

1

0

High-throughput

0.518

High

1150546

TRADD
Tumor necrosis factor receptor type 1-associated DEATH domain protein

1

0

High-throughput

0.513

High

1315948

TESK2
Dual specificity testis-specific protein kinase 2

1

0

High-throughput

0.513

High

437731

HEPS
Serine protease hepsin

1

11

High-throughput

0.489

High

1101381

SG2A2
Mammaglobin-A

1

6

High-throughput

0.489

High

1308261

HDBP1
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1

1

1

High-throughput

0.489

High

1315942

GGH
Gamma-glutamyl hydrolase

1

1

High-throughput

0.489

High

1315946

LCFC1
Sperm-egg fusion protein LLCFC1

1

2

High-throughput

0.489

High

181906

SMAD9
Mothers against decapentaplegic homolog 9

1

0

High-throughput

0.486

High

1032197

EXOSX
Exosome complex component 10

1

0

High-throughput

0.486

High

1085508

ARHG5
Rho guanine nucleotide exchange factor 5

1

0

High-throughput

0.460

High

1209097

EXOS6
Exosome complex component MTR3

1

0

High-throughput

0.460

High

1315949

NKX31
Homeobox protein Nkx-3.1

1

0

Small-scale

0.460

High

623435

RO52
E3 ubiquitin-protein ligase TRIM21

1

0

High-throughput

0.458

High

872516

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

1150928

TRIPB
Thyroid receptor-interacting protein 11

1

0

High-throughput

0.458

High

1315947

SNX27
Sorting nexin-27

1

0

High-throughput

0.458

High

1315955

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1315952

DISC1
Disrupted in schizophrenia 1 protein

1

1

High-throughput

0.457

High

844825

EAA1
Excitatory amino acid transporter 1

1

4

High-throughput

0.445

High

1315938

ZNT7
Zinc transporter 7

1

14

High-throughput

0.445

High

1315939

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

14

High-throughput

0.445

High

1315940

S7A14
Solute carrier family 7 member 14

1

6

High-throughput

0.445

High

1109320

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

0

High-throughput

0.438

High

1315944

SPTCS
Spatacsin

1

0

Small-scale

0.438

High

218439

TGON2
Trans-Golgi network integral membrane protein 2

1

10

High-throughput

0.437

High

693024

DPP4
Dipeptidyl peptidase 4

1

2

High-throughput

0.437

High

1249005

LMBRL
Protein LMBR1L

1

2

High-throughput

0.437

High

1254577

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

1315937

PLD6
Mitochondrial cardiolipin hydrolase

1

1

High-throughput

0.437

High

1315943

PLD4
5'-3' exonuclease PLD4

1

2

High-throughput

0.437

High

1315953

TMPS4
Transmembrane protease serine 4

1

11

High-throughput

0.437

High

1060369

SLC31
Amino acid transporter heavy chain SLC3A1

1

2

High-throughput

0.407

High

1133790

SL9A5
Sodium/hydrogen exchanger 5

1

3

High-throughput

0.407

High

1139491

S39AE
Metal cation symporter ZIP14

1

20

High-throughput

0.407

High

1242163

NPAL3
NIPA-like protein 3

1

4

High-throughput

0.407

High

1271242

SV2B
Synaptic vesicle glycoprotein 2B

1

2

High-throughput

0.407

High

1315936

S39AB
Zinc transporter ZIP11

1

20

High-throughput

0.407

High

1315941

S39A7
Zinc transporter SLC39A7

1

20

High-throughput

0.407

High

1315954

S22AB
Solute carrier family 22 member 11

1

3

High-throughput

0.407

High

1315945

LCOR
Ligand-dependent corepressor

1

0

High-throughput

0.282

High

555506

SKIL
Ski-like protein

1

0

High-throughput

0.265

Low

106244

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

293993

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

1315950

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.249

Low

2110

TVA20
T cell receptor alpha variable 20

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025