Protein: MED1
Mediator of RNA polymerase II transcription subunit 1 (Mediator complex subunit 1) (dTRAP220)

Gene: MED1
Organism: Drosophila melanogaster
Interactions: 69
UniProt ID: Q9VP05

Gene Ontology (top 5):
GO:0003712 - transcription coregulator activity
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0016592 - mediator complex
GO:0045944 - positive regulation of transcription by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1483008

MED4
Mediator of RNA polymerase II transcription subunit 4

1

1

High-throughput

0.575

High

1483014

MED19
Mediator of RNA polymerase II transcription subunit 19

2

1

Small-scale

0.571

High

628542

USP
Protein ultraspiracle

1

17

Small-scale

0.479

High

756501

ECR
Ecdysone receptor

1

20

Small-scale

0.479

High

909939

PNR
GATA-binding factor A

1

7

Small-scale

0.479

High

909951

SRP
Box A-binding factor

1

8

Small-scale

0.479

High

1192913

YAP1
Transcriptional coactivator yorkie

1

4

Small-scale

0.479

High

1269627

MED13
Mediator of RNA polymerase II transcription subunit 13

1

2

Small-scale

0.479

High

1483012

CDK8
Cyclin-dependent kinase 8

1

3

Small-scale

0.479

High

1483022

LOZEN
Protein lozenge

1

2

Small-scale

0.479

High

58503

MED8
Mediator of RNA polymerase II transcription subunit 8

1

1

High-throughput

0.445

High

84985

B7Z126
non-specific serine/threonine protein kinase

1

4

High-throughput

0.445

High

1019295

MED20
Mediator of RNA polymerase II transcription subunit 20

1

2

High-throughput

0.445

High

1263898

Q7K012
Brahma associated protein 55kD

1

5

High-throughput

0.445

High

1267150

Q7KHL0
Bancal protein

1

2

High-throughput

0.445

High

1302892

MED31
Mediator of RNA polymerase II transcription subunit 31

1

1

High-throughput

0.445

High

1303624

OSA
Trithorax group protein osa

1

15

High-throughput

0.445

High

1377792

EBI
F-box-like/WD repeat-containing protein ebi

1

1

High-throughput

0.445

High

1427992

MED10
Mediator of RNA polymerase II transcription subunit 10

1

1

High-throughput

0.445

High

1428101

MED7
Mediator of RNA polymerase II transcription subunit 7

1

1

High-throughput

0.445

High

1471834

MED25
Mediator of RNA polymerase II transcription subunit 25

1

3

High-throughput

0.445

High

1472607

MED17
Mediator of RNA polymerase II transcription subunit 17

1

1

High-throughput

0.445

High

1475511

CARM1
Probable histone-arginine methyltransferase CARMER

1

2

High-throughput

0.445

High

1476533

DDX3
ATP-dependent RNA helicase bel

1

4

High-throughput

0.445

High

1480040

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

3

High-throughput

0.445

High

1482731

MED27
Mediator of RNA polymerase II transcription subunit 27

1

1

High-throughput

0.445

High

1483007

MED1
Mediator of RNA polymerase II transcription subunit 1

1

17

High-throughput

0.445

High

1483010

MED24
Mediator of RNA polymerase II transcription subunit 24

1

1

High-throughput

0.445

High

1483011

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

2

High-throughput

0.445

High

1483015

MED11
Mediator of RNA polymerase II transcription subunit 11

1

1

High-throughput

0.445

High

1483018

MED30
Mediator of RNA polymerase II transcription subunit 30

1

1

High-throughput

0.445

High

1483019

MED14
Mediator of RNA polymerase II transcription subunit 14

1

3

High-throughput

0.445

High

1483020

MED23
Mediator of RNA polymerase II transcription subunit 23

1

2

High-throughput

0.445

High

1483021

MED16
Mediator of RNA polymerase II transcription subunit 16

1

1

High-throughput

0.445

High

1171975

Q24113
Protein no-on-transient A

1

0

High-throughput

0.426

High

1261422

Q7JQT8
LD41464p

1

0

High-throughput

0.426

High

1343909

Q8SXP8
TAR DNA-binding protein 43

1

0

High-throughput

0.426

High

1479420

NFS1
Cysteine desulfurase, mitochondrial

1

0

High-throughput

0.426

High

1480261

Q9VL29
GEO11246p1

1

0

High-throughput

0.426

High

51926

PO210
Nuclear pore membrane glycoprotein 210

1

1

High-throughput

0.407

High

438009

PYR1
Multifunctional protein r

1

1

High-throughput

0.407

High

753214

GLT
Glutactin

1

3

High-throughput

0.407

High

1071098

Q0KIE7
Ankyrin, isoform B

1

3

High-throughput

0.407

High

1175290

NETB
Netrin-B

1

6

High-throughput

0.407

High

1265393

Q7K2L7
GH27120p

1

2

High-throughput

0.407

High

1265752

Q7K3H0
LD28067p

1

2

High-throughput

0.407

High

1440692

LAR4
La-related protein Larp4B

1

1

High-throughput

0.407

High

1473322

ATD3A
ATPase family AAA domain-containing protein 3A homolog

1

3

High-throughput

0.407

High

1474981

IPO9
Importin-9

1

5

High-throughput

0.407

High

1475541

Q9VH62
LD44003p

1

5

High-throughput

0.407

High

1478317

Q9VJD1
Glucosidase 2 subunit beta

1

2

High-throughput

0.407

High

1479190

Q9VK57
PIH1 domain-containing protein 1

1

1

High-throughput

0.407

High

1482037

Q9VMV5
Viking, isoform A

1

14

High-throughput

0.407

High

1483013

Q9VUB7
PAX-interacting protein 1

1

3

High-throughput

0.407

High

1483017

Q9W0L7
ubiquitinyl hydrolase 1

1

2

High-throughput

0.407

High

1483023

Q9Y162
vesicle-fusing ATPase

1

3

High-throughput

0.407

High

838840

GRK
Protein gurken

1

0

High-throughput

0.282

High

1261756

Q7JRA5
RH66388p

1

0

High-throughput

0.265

Low

84725

UNR
RNA-binding protein Unr

1

0

High-throughput

0.232

Low

834876

IF2B
Eukaryotic translation initiation factor 2 subunit 2

1

0

High-throughput

0.232

Low

1069203

Q0E8E8
Phosphate carrier protein, mitochondrial

1

0

High-throughput

0.232

Low

1069934

Q0E996
Eukaryotic translation initiation factor 4 gamma 2

1

0

High-throughput

0.232

Low

1321143

Q8MRW1
SD19278p

1

0

High-throughput

0.232

Low

1378932

Q960F7
SD03629p

1

0

High-throughput

0.232

Low

1465629

Q9V470
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial

1

0

High-throughput

0.232

Low

1468488

Q9VAW3
glutamine--fructose-6-phosphate transaminase

1

0

High-throughput

0.232

Low

1483009

ACADM
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial

1

0

High-throughput

0.232

Low

1483016

IDH3A
Probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025