Protein: COA1
Cytochrome c oxidase assembly factor 1 homolog (Mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 15 kDa)

Gene: COA1
Organism: Homo sapiens
Interactions: 49
UniProt ID: Q9GZY4

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005829 - cytosol
GO:0032981 - mitochondrial respiratory chain complex I assembly
GO:0033617 - mitochondrial cytochrome c oxidase assembly

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1410307

ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

3

0

High-throughput

0.638

High

1429116

ACAD9
Complex I assembly factor ACAD9, mitochondrial

3

0

High-throughput

0.638

High

1192288

ZACN
Ligand-gated cation channel ZACN

3

2

High-throughput

0.609

High

855386

5HT3A
5-hydroxytryptamine receptor 3A

2

1

High-throughput

0.574

High

174081

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

0

High-throughput

0.513

High

333598

NDUC2
NADH dehydrogenase [ubiquinone] 1 subunit C2

1

0

High-throughput

0.513

High

1272556

CSN6
COP9 signalosome complex subunit 6

1

0

High-throughput

0.513

High

1429114

S22A4
Solute carrier family 22 member 4

1

0

High-throughput

0.513

High

1429122

CIA30
Complex I intermediate-associated protein 30, mitochondrial

1

0

High-throughput

0.513

High

247424

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

0

Small-scale

0.458

High

414581

P53
Cellular tumor antigen p53

1

0

Small-scale

0.458

High

1120101

COX17
Cytochrome c oxidase copper chaperone

1

0

Small-scale

0.458

High

1206818

COA6
Cytochrome c oxidase assembly factor 6 homolog

1

0

Small-scale

0.458

High

1429119

NCDN
Neurochondrin

1

0

High-throughput

0.458

High

1337945

ZNT7
Zinc transporter 7

1

1

High-throughput

0.445

High

328400

NDUB8
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial

1

0

Small-scale

0.426

High

360292

COX1
Cytochrome c oxidase subunit 1

1

0

Small-scale

0.426

High

457683

TBB5
Tubulin beta chain

1

0

High-throughput

0.426

High

1093173

STK4
Serine/threonine-protein kinase 4

1

0

High-throughput

0.426

High

1149629

SURF1
Surfeit locus protein 1

1

0

Small-scale

0.426

High

1235740

SCMC2
Mitochondrial adenyl nucleotide antiporter SLC25A25

1

0

High-throughput

0.426

High

1415764

TIM21
Mitochondrial import inner membrane translocase subunit Tim21

1

0

Small-scale

0.426

High

1429118

ATD3A
ATPase family AAA domain-containing protein 3A

1

0

High-throughput

0.426

High

1429121

COA3
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial

1

0

Small-scale

0.426

High

1363440

S39A7
Zinc transporter SLC39A7

1

1

High-throughput

0.407

High

1421350

S39A8
Metal cation symporter ZIP8

1

1

High-throughput

0.407

High

1429123

ZNT1
Proton-coupled zinc antiporter SLC30A1

1

1

High-throughput

0.407

High

1351232

MCLN3
Mucolipin-3

3

0

High-throughput

0.347

High

1232014

GL1AD
DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5

3

0

High-throughput

0.334

High

1365126

SL9A6
Sodium/hydrogen exchanger 6

2

0

High-throughput

0.328

High

1391921

RN185
E3 ubiquitin-protein ligase RNF185

2

0

High-throughput

0.328

High

848563

MAGA8
Melanoma-associated antigen 8

1

0

High-throughput

0.279

Low

851212

ACHA4
Neuronal acetylcholine receptor subunit alpha-4

1

0

High-throughput

0.279

Low

904240

P2RX1
P2X purinoceptor 1

1

0

High-throughput

0.279

Low

1053835

KDSR
3-ketodihydrosphingosine reductase

1

0

High-throughput

0.279

Low

1429115

TTYH1
Protein tweety homolog 1

1

0

High-throughput

0.279

Low

1429117

CRLF2
Cytokine receptor-like factor 2

1

0

High-throughput

0.279

Low

589635

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

696449

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

769124

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1243719

RFWD3
E3 ubiquitin-protein ligase RFWD3

1

0

Small-scale

0.249

Low

1348207

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.249

Low

1429120

S23A2
Solute carrier family 23 member 2

1

0

High-throughput

0.249

Low

58929

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

0

High-throughput

0.232

Low

505976

MYZAP
Myocardial zonula adherens protein

1

0

High-throughput

0.232

Low

506026

GRL1A
DNA-directed RNA polymerase II subunit GRINL1A

1

0

High-throughput

0.232

Low

845125

EAA3
Excitatory amino acid transporter 3

1

0

High-throughput

0.232

Low

886129

CXCR3
C-X-C chemokine receptor type 3

1

0

High-throughput

0.232

Low

1389583

SAAL1
Protein SAAL1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025