Protein: NDUB8
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (Complex I-ASHI) (CI-ASHI) (NADH-ubiquinone oxidoreductase ASHI subunit)

Gene: NDUB8, NDUFB8
Organism: Homo sapiens
Interactions: 94
UniProt ID: O95169

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005759 - mitochondrial matrix
GO:0006120 - mitochondrial electron transport, NADH to ubiquinone
GO:0008137 - NADH dehydrogenase (ubiquinone) activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

328340

NDUBA
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10

2

1

High-throughput

0.754

High

283746

NDUS3
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

5

0

High-throughput

0.688

High

328347

NU5M
NADH-ubiquinone oxidoreductase chain 5

1

0

High-throughput

0.656

High

328352

NDUB7
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7

1

0

High-throughput

0.656

High

328365

NDUA8
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8

3

0

High-throughput

0.638

High

328394

ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

3

0

High-throughput

0.638

High

223584

NDUB5
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial

3

0

High-throughput

0.634

High

328376

NDUA9
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial

3

0

High-throughput

0.634

High

328378

PRRT2
Proline-rich transmembrane protein 2

4

1

High-throughput

0.630

High

328406

NDUBB
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial

2

1

High-throughput

0.628

High

328392

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

3

0

High-throughput

0.622

High

328338

VAPB
Vesicle-associated membrane protein-associated protein B/C

3

1

High-throughput

0.609

High

209721

NDUS4
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial

2

0

High-throughput

0.602

High

231185

NDUS5
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5

2

0

High-throughput

0.602

High

275218

NDUS7
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial

2

0

High-throughput

0.602

High

278595

NDUS6
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial

2

0

High-throughput

0.602

High

328411

NDUAC
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12

2

0

High-throughput

0.602

High

328354

NDUV2
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial

2

0

High-throughput

0.576

High

183801

NDUA1
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1

1

0

High-throughput

0.513

High

223684

NDUB3
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3

1

0

High-throughput

0.513

High

228774

SCO2
Protein SCO2 homolog, mitochondrial

1

0

High-throughput

0.513

High

328337

NDUA7
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7

1

0

High-throughput

0.513

High

328339

NDUC2
NADH dehydrogenase [ubiquinone] 1 subunit C2

1

0

High-throughput

0.513

High

328341

TOM40
Mitochondrial import receptor subunit TOM40 homolog

1

0

High-throughput

0.513

High

328363

RAB7A
Ras-related protein Rab-7a

1

0

High-throughput

0.513

High

328366

NDUV3
NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial

1

0

High-throughput

0.513

High

328379

NDUAB
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11

1

0

High-throughput

0.513

High

328380

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

328381

NDUF2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2

1

0

High-throughput

0.513

High

328401

S22A4
Solute carrier family 22 member 4

1

0

High-throughput

0.513

High

328404

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

1

0

High-throughput

0.513

High

328416

NDUB9
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9

1

0

High-throughput

0.513

High

328359

CUX1
Homeobox protein cut-like 1

1

1

High-throughput

0.489

High

328391

CREL1
Protein disulfide isomerase CRELD1

1

1

High-throughput

0.489

High

328407

VAPA
Vesicle-associated membrane protein-associated protein A

1

1

High-throughput

0.489

High

328371

CYC
Cytochrome c

1

1

High-throughput

0.479

High

137596

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

0

High-throughput

0.458

High

328342

COX1
Cytochrome c oxidase subunit 1

1

0

Small-scale

0.458

High

328350

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

1

0

High-throughput

0.458

High

328393

IMP1L
Mitochondrial inner membrane protease subunit 1

1

0

High-throughput

0.458

High

328395

TMM70
Transmembrane protein 70, mitochondrial

1

0

High-throughput

0.458

High

328396

MIC26
MICOS complex subunit MIC26

1

0

High-throughput

0.458

High

328399

CC90B
Coiled-coil domain-containing protein 90B, mitochondrial

1

0

High-throughput

0.458

High

328402

PARL
Presenilin-associated rhomboid-like protein, mitochondrial

1

0

High-throughput

0.458

High

222603

PRC1
Protein regulator of cytokinesis 1

1

1

High-throughput

0.437

High

328346

DQB1
HLA class II histocompatibility antigen, DQ beta 1 chain

1

1

High-throughput

0.437

High

328348

COX6C
Cytochrome c oxidase subunit 6C

1

0

Small-scale

0.426

High

328349

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

328367

NDUA6
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6

1

0

Small-scale

0.426

High

328397

TIM21
Mitochondrial import inner membrane translocase subunit Tim21

1

0

Small-scale

0.426

High

328400

COA1
Cytochrome c oxidase assembly factor 1 homolog

1

0

Small-scale

0.426

High

328345

DRB1
HLA class II histocompatibility antigen, DRB1 beta chain

1

1

High-throughput

0.407

High

328370

S35B1
Solute carrier family 35 member B1

1

1

High-throughput

0.407

High

328373

CASP
Protein CASP

1

1

High-throughput

0.407

High

328386

S35B2
Adenosine 3'-phospho 5'-phosphosulfate transporter 1

1

1

High-throughput

0.407

High

328377

ENPP6
Glycerophosphocholine cholinephosphodiesterase ENPP6

4

0

High-throughput

0.360

High

328390

WBP1
WW domain-binding protein 1

3

0

High-throughput

0.347

High

328355

FUT1
Galactoside alpha-(1,2)-fucosyltransferase 1

2

0

High-throughput

0.328

High

328356

NK1R
Substance-P receptor

2

0

High-throughput

0.328

High

328362

AGRE5
Adhesion G protein-coupled receptor E5

2

0

High-throughput

0.328

High

328385

GALT6
Polypeptide N-acetylgalactosaminyltransferase 6

2

0

High-throughput

0.328

High

328387

SPP2B
Signal peptide peptidase-like 2B

2

0

High-throughput

0.328

High

328398

YIPF3
Protein YIPF3

2

0

High-throughput

0.328

High

328358

PROF2
Profilin-2

1

0

High-throughput

0.282

High

328360

ZAP70
Tyrosine-protein kinase ZAP-70

1

0

High-throughput

0.282

High

328382

VA0D2
V-type proton ATPase subunit d 2

1

0

High-throughput

0.282

High

328405

EI2BG
Translation initiation factor eIF2B subunit gamma

1

0

High-throughput

0.282

High

328409

PIM2
Serine/threonine-protein kinase pim-2

1

0

High-throughput

0.282

High

230732

EXTL3
Exostosin-like 3

1

0

High-throughput

0.279

Low

328343

GLUC
Pro-glucagon [Cleaved into: Glicentin; Glicentin-related polypeptide

1

0

High-throughput

0.279

Low

328344

IL2RA
Interleukin-2 receptor subunit alpha

1

0

High-throughput

0.279

Low

328353

RL35A
Large ribosomal subunit protein eL33

1

0

High-throughput

0.279

Low

328357

V2R
Vasopressin V2 receptor

1

0

High-throughput

0.279

Low

328361

CXA8
Gap junction alpha-8 protein

1

0

High-throughput

0.279

Low

328364

CP2J2
Cytochrome P450 2J2

1

0

High-throughput

0.279

Low

328383

XXLT1
Xyloside xylosyltransferase 1

1

0

High-throughput

0.279

Low

328384

SIDT2
SID1 transmembrane family member 2

1

0

High-throughput

0.279

Low

328389

AQP3
Aquaporin-3

1

0

High-throughput

0.279

Low

328408

TM63C
Osmosensitive cation channel TMEM63C

1

0

High-throughput

0.279

Low

328412

GPR34
Probable G-protein coupled receptor 34

1

0

High-throughput

0.279

Low

328415

GOT1B
Vesicle transport protein GOT1B

1

0

High-throughput

0.279

Low

139673

CAC1A
Voltage-dependent P/Q-type calcium channel subunit alpha-1A

1

0

High-throughput

0.265

Low

328368

AP2B1
AP-2 complex subunit beta

1

0

High-throughput

0.261

Low

328375

ITSN1
Intersectin-1

1

0

High-throughput

0.261

Low

105004

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

328351

TCTP
Translationally-controlled tumor protein

1

0

High-throughput

0.249

Low

328369

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

328403

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

328410

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.249

Low

328372

ASPH
Aspartyl/asparaginyl beta-hydroxylase

1

0

High-throughput

0.232

Low

328374

MFS10
Major facilitator superfamily domain-containing protein 10

1

0

High-throughput

0.232

Low

328388

GTR12
Solute carrier family 2, facilitated glucose transporter member 12

1

0

High-throughput

0.232

Low

328413

GAB2
GRB2-associated-binding protein 2

1

0

High-throughput

0.232

Low

328414

ITM2B
Integral membrane protein 2B

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025