Protein: PRS23
Serine protease 23 (EC 3.4.21.-) (Putative secreted protein Zsig13)

Gene: PRS23, PRSS23
Organism: Homo sapiens
Interactions: 52
UniProt ID: O95084

Gene Ontology (top 5):
GO:0004252 - serine-type endopeptidase activity
GO:0005634 - nucleus
GO:0005788 - endoplasmic reticulum lumen
GO:0006508 - proteolysis
GO:0070062 - extracellular exosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

326247

ACTB
Actin, cytoplasmic 1

3

1

High-throughput

0.667

High

326248

B2MG
Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3]

1

0

High-throughput

0.663

High

326229

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.647

High

326237

CO5A1

2

0

High-throughput

0.602

High

326251

LRP2
Low-density lipoprotein receptor-related protein 2

1

0

High-throughput

0.586

High

326267

SC11C
Signal peptidase complex catalytic subunit SEC11C

2

0

High-throughput

0.580

High

326227

HBD
Hemoglobin subunit delta

1

0

High-throughput

0.578

High

326250

ACTG
Actin, cytoplasmic 2

1

1

High-throughput

0.541

High

193478

PDPK1
3-phosphoinositide-dependent protein kinase 1

1

0

High-throughput

0.518

High

314975

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.518

High

326234

ADT3
ADP/ATP translocase 3

1

0

High-throughput

0.518

High

326238

GLYC
Serine hydroxymethyltransferase, cytosolic

1

0

High-throughput

0.518

High

326239

HSP74
Heat shock 70 kDa protein 4

1

0

High-throughput

0.518

High

326245

FXR1
RNA-binding protein FXR1

1

0

High-throughput

0.518

High

326249

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

0

High-throughput

0.518

High

326255

NIPBL
Nipped-B-like protein

1

0

High-throughput

0.518

High

326259

GALD1
Glutamine amidotransferase-like class 1 domain-containing protein 1

1

0

High-throughput

0.518

High

326262

HTF4
Transcription factor 12

1

0

High-throughput

0.518

High

326263

CHP1
Calcineurin B homologous protein 1

1

0

High-throughput

0.518

High

326264

PHF23
PHD finger protein 23

1

0

High-throughput

0.518

High

326268

RGAP1
Rac GTPase-activating protein 1

1

0

High-throughput

0.518

High

326231

SRPRA
Signal recognition particle receptor subunit alpha

1

0

High-throughput

0.513

High

326235

PGFRA
Platelet-derived growth factor receptor alpha

1

0

High-throughput

0.513

High

326240

CH3L1
Chitinase-3-like protein 1

1

0

High-throughput

0.513

High

326252

BAX
Apoptosis regulator BAX

1

0

High-throughput

0.513

High

326230

H10
Histone H1.0

1

0

High-throughput

0.493

High

326232

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.480

High

217648

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.479

High

326236

EGR1
Early growth response protein 1

1

0

High-throughput

0.458

High

326244

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

326270

CHM4B
Charged multivesicular body protein 4b

1

0

High-throughput

0.458

High

326241

RL4
Large ribosomal subunit protein uL4

1

0

High-throughput

0.438

High

62081

KLRG2
Killer cell lectin-like receptor subfamily G member 2

2

0

High-throughput

0.328

High

326228

CRP

2

0

High-throughput

0.328

High

326258

UBR1
E3 ubiquitin-protein ligase UBR1

2

0

High-throughput

0.328

High

326242

CNDD3
Condensin-2 complex subunit D3

1

0

High-throughput

0.282

High

326243

GRK6
G protein-coupled receptor kinase 6

1

0

High-throughput

0.282

High

326246

EFNA3
Ephrin-A3

1

0

High-throughput

0.282

High

326254

JIP2
C-Jun-amino-terminal kinase-interacting protein 2

1

0

High-throughput

0.282

High

326265

NOC4L
Nucleolar complex protein 4 homolog

1

0

High-throughput

0.282

High

326269

TM222
Transmembrane protein 222

1

0

High-throughput

0.282

High

326272

ODF2L
Protein BCAP

1

0

High-throughput

0.282

High

326273

TPPC4
Trafficking protein particle complex subunit 4

1

0

High-throughput

0.282

High

282809

CRLF1
Cytokine receptor-like factor 1

1

0

High-throughput

0.279

Low

326233

CCL3
C-C motif chemokine 3

1

0

High-throughput

0.279

Low

326253

SG2A2
Mammaglobin-A

1

0

High-throughput

0.279

Low

326256

CTR9
RNA polymerase-associated protein CTR9 homolog

1

0

High-throughput

0.279

Low

326257

NOP9
Nucleolar protein 9

1

0

High-throughput

0.279

Low

326260

CA054
Uncharacterized protein C1orf54

1

0

High-throughput

0.279

Low

326261

TET5A
Terminal nucleotidyltransferase 5A

1

0

High-throughput

0.279

Low

326266

C1QT7
Complement C1q tumor necrosis factor-related protein 7

1

0

High-throughput

0.279

Low

326271

ANLN
Anillin

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025