Protein: TRI50
E3 ubiquitin-protein ligase TRIM50 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TRIM50) (Tripartite motif-containing protein 50)

Gene: TRI50, TRIM50
Organism: Homo sapiens
Interactions: 52
UniProt ID: Q86XT4

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0008270 - zinc ion binding
GO:0016567 - protein ubiquitination
GO:0042802 - identical protein binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

849360

UB2D1
Ubiquitin-conjugating enzyme E2 D1

4

20

Small-scale

0.888

High

919773

UB2D2
Ubiquitin-conjugating enzyme E2 D2

3

20

Small-scale

0.845

High

1204900

UB2E3
Ubiquitin-conjugating enzyme E2 E3

3

20

Small-scale

0.845

High

1204911

UB2D4
Ubiquitin-conjugating enzyme E2 D4

3

20

Small-scale

0.845

High

1204894

TRI50
E3 ubiquitin-protein ligase TRIM50

3

16

Small-scale

0.839

High

536904

TRI27
Zinc finger protein RFP

2

16

High-throughput

0.783

High

872183

RD23A
UV excision repair protein RAD23 homolog A

2

12

High-throughput

0.783

High

896330

UBE2K
Ubiquitin-conjugating enzyme E2 K

2

20

High-throughput

0.783

High

1020779

TRAF2
TNF receptor-associated factor 2

2

19

High-throughput

0.783

High

1204896

LNX1
E3 ubiquitin-protein ligase LNX

2

7

High-throughput

0.783

High

1204902

UB2E2
Ubiquitin-conjugating enzyme E2 E2

3

20

Small-scale

0.755

High

1204895

IQUB
IQ motif and ubiquitin-like domain-containing protein

2

1

High-throughput

0.700

High

1204906

UBTD1
Ubiquitin domain-containing protein 1

2

3

High-throughput

0.700

High

326703

SNAI1
Zinc finger protein SNAI1

2

20

Small-scale

0.624

High

1204909

HDAC6
Histone deacetylase 6

2

5

Small-scale

0.624

High

851837

UB2E1
Ubiquitin-conjugating enzyme E2 E1

1

20

Small-scale

0.621

High

895838

UB2D3
Ubiquitin-conjugating enzyme E2 D3

1

20

Small-scale

0.621

High

896483

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

20

Small-scale

0.621

High

239460

PLPL9
85/88 kDa calcium-independent phospholipase A2

2

5

High-throughput

0.606

High

271136

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

2

20

High-throughput

0.606

High

278302

PIAS2
E3 SUMO-protein ligase PIAS2

2

7

High-throughput

0.606

High

307193

KLHL2
Kelch-like protein 2

2

2

High-throughput

0.606

High

883364

UBS3A
Ubiquitin-associated and SH3 domain-containing protein A

2

9

High-throughput

0.606

High

989694

CDK18
Cyclin-dependent kinase 18

2

6

High-throughput

0.606

High

1151543

XAF1
XIAP-associated factor 1

2

2

High-throughput

0.606

High

1190634

ZN438
Zinc finger protein 438

2

17

High-throughput

0.606

High

1204898

HMHA1
Rho GTPase-activating protein 45 [Cleaved into: Minor histocompatibility antigen HA-1

2

4

High-throughput

0.606

High

1204901

GCC1
GRIP and coiled-coil domain-containing protein 1

2

7

High-throughput

0.606

High

1204903

AP4AT
AP-4 complex accessory subunit Tepsin

2

2

High-throughput

0.606

High

1204905

TSSK3
Testis-specific serine/threonine-protein kinase 3

2

2

High-throughput

0.606

High

1204899

LMBL2
Lethal(3)malignant brain tumor-like protein 2

2

0

High-throughput

0.580

High

1204908

SPG21
Maspardin

2

0

High-throughput

0.580

High

523048

SRC
Proto-oncogene tyrosine-protein kinase Src

1

8

Small-scale

0.578

High

1204904

NLRP3
NACHT, LRR and PYD domains-containing protein 3

1

13

Small-scale

0.561

High

833915

CLK2
Dual specificity protein kinase CLK2

2

4

High-throughput

0.553

High

1110172

T10IP
Testis-specific protein 10-interacting protein

2

2

High-throughput

0.553

High

1169327

ZN620
Zinc finger protein 620

2

20

High-throughput

0.553

High

1204910

RSP14
Radial spoke head 14 homolog

2

7

High-throughput

0.553

High

838098

MEOX2
Homeobox protein MOX-2

1

14

High-throughput

0.481

High

805542

BRCC3
Lys-63-specific deubiquitinase BRCC36

1

2

Small-scale

0.479

High

992593

ACK1
Activated CDC42 kinase 1

1

16

Small-scale

0.479

High

1036706

SQSTM
Sequestosome-1

1

6

Small-scale

0.479

High

1054158

BECN1
Beclin-1

1

3

Small-scale

0.479

High

1204897

NEK7
Serine/threonine-protein kinase Nek7

1

6

Small-scale

0.479

High

1151101

Q6FHY5
MEOX2 protein

1

14

High-throughput

0.470

High

1204907

NOD2
Nucleotide-binding oligomerization domain-containing protein 2

1

13

Small-scale

0.457

High

100918

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

61789

F221B
Protein FAM221B

2

0

High-throughput

0.316

High

1127551

EFHC2
EF-hand domain-containing family member C2

2

0

High-throughput

0.316

High

1185179

EPMIP
EPM2A-interacting protein 1

2

0

High-throughput

0.316

High

262499

TULP3
Tubby-related protein 3

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024