Protein: P2RX2
P2X purinoceptor 2 (P2X2) (ATP receptor) (Purinergic receptor)

Gene: P2RX2
Organism: Homo sapiens
Interactions: 67
UniProt ID: Q9UBL9

Gene Ontology (top 5):
GO:0001614 - purinergic nucleotide receptor activity
GO:0001666 - response to hypoxia
GO:0002931 - response to ischemia
GO:0003029 - detection of hypoxic conditions in blood by carotid body chemoreceptor signaling
GO:0004931 - extracellularly ATP-gated monoatomic cation channel activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

932005

EPHB4
Ephrin type-B receptor 4

2

1

High-throughput

0.628

High

1108736

TBB3
Tubulin beta-3 chain

2

1

High-throughput

0.628

High

1350010

SPPL3
Signal peptide peptidase-like 3

2

1

High-throughput

0.628

High

301743

WFS1
Wolframin

2

0

High-throughput

0.602

High

1251225

DUSTY
Dual serine/threonine and tyrosine protein kinase

2

0

High-throughput

0.602

High

1291963

LRP11
Low-density lipoprotein receptor-related protein 11

2

0

High-throughput

0.602

High

1316782

WDFY3
WD repeat and FYVE domain-containing protein 3

2

0

High-throughput

0.602

High

1453355

E2AK3
Eukaryotic translation initiation factor 2-alpha kinase 3

2

0

High-throughput

0.602

High

299891

C1QRF
C1q-related factor

2

1

High-throughput

0.574

High

699218

CALX
Calnexin

2

1

High-throughput

0.574

High

1191996

TBB8
Tubulin beta-8 chain

2

1

High-throughput

0.574

High

1194720

GXLT1
Glucoside xylosyltransferase 1

2

1

High-throughput

0.574

High

1273293

HS2ST
Heparan sulfate 2-O-sulfotransferase 1

2

1

High-throughput

0.574

High

1336136

GLT11
Polypeptide N-acetylgalactosaminyltransferase 11

2

2

High-throughput

0.574

High

576692

GBRA1
Gamma-aminobutyric acid receptor subunit alpha-1

1

4

Small-scale

0.561

High

61146

T131L
Transmembrane protein 131-like

1

1

High-throughput

0.536

High

287622

LRP6
Low-density lipoprotein receptor-related protein 6

1

1

High-throughput

0.536

High

376559

LDLR
Low-density lipoprotein receptor

1

1

High-throughput

0.536

High

565728

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

4

High-throughput

0.536

High

720436

ACHA5
Neuronal acetylcholine receptor subunit alpha-5

1

4

High-throughput

0.536

High

1006039

ASIC1
Acid-sensing ion channel 1

1

1

High-throughput

0.536

High

1023402

AT2C1
Calcium-transporting ATPase type 2C member 1

1

4

High-throughput

0.536

High

1180978

HFE
Hereditary hemochromatosis protein

1

1

High-throughput

0.536

High

1309810

IPRI
Inositol 1,4,5-trisphosphate receptor-interacting protein

1

1

High-throughput

0.536

High

1435770

AT133
Polyamine-transporting ATPase 13A3

1

3

High-throughput

0.536

High

1458488

ST14
Suppressor of tumorigenicity 14 protein

1

2

High-throughput

0.536

High

354186

CLPT1
Putative lipid scramblase CLPTM1

1

0

High-throughput

0.513

High

535625

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.513

High

567783

TF
Tissue factor

1

0

High-throughput

0.513

High

580850

PVR
Poliovirus receptor

1

0

High-throughput

0.513

High

1105256

S39A6
Zinc transporter ZIP6

1

0

High-throughput

0.513

High

1159183

SGCB
Beta-sarcoglycan

1

0

High-throughput

0.513

High

1213216

AGRF1
Adhesion G-protein coupled receptor F1

1

0

High-throughput

0.513

High

1395131

TMX3
Protein disulfide-isomerase TMX3

1

0

High-throughput

0.513

High

1417364

S26A6
Solute carrier family 26 member 6

1

0

High-throughput

0.513

High

1458487

JAG2
Protein jagged-2

1

0

High-throughput

0.513

High

324054

CSTN1
Calsyntenin-1

1

2

High-throughput

0.489

High

1022492

IDD
Integral membrane protein DGCR2/IDD

1

3

High-throughput

0.489

High

1295804

C1QL4
Complement C1q-like protein 4

1

1

High-throughput

0.489

High

1309654

GLBL2
Beta-galactosidase-1-like protein 2

1

1

High-throughput

0.489

High

1410973

CSTN3
Calsyntenin-3

1

2

High-throughput

0.489

High

608005

ACHB2
Neuronal acetylcholine receptor subunit beta-2

1

4

Small-scale

0.479

High

733722

ACHA3
Neuronal acetylcholine receptor subunit alpha-3

1

4

Small-scale

0.479

High

851232

ACHA4
Neuronal acetylcholine receptor subunit alpha-4

1

4

Small-scale

0.479

High

1133240

STAR3
StAR-related lipid transfer protein 3

2

0

High-throughput

0.328

High

1386108

EVI5L
EVI5-like protein

2

0

High-throughput

0.328

High

1439090

K1586
E3 SUMO-protein ligase KIAA1586

2

0

High-throughput

0.328

High

1458489

FKBP7
Peptidyl-prolyl cis-trans isomerase FKBP7

2

0

High-throughput

0.328

High

881747

FNTB
Protein farnesyltransferase subunit beta

1

0

High-throughput

0.279

Low

1143692

NOMO1
BOS complex subunit NOMO1

1

0

High-throughput

0.279

Low

1197289

MBRL
Membralin

1

0

High-throughput

0.279

Low

1325851

D2HDH
D-2-hydroxyglutarate dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

1366372

GPI8
GPI-anchor transamidase

1

0

High-throughput

0.279

Low

1382232

CCD47
PAT complex subunit CCDC47

1

0

High-throughput

0.279

Low

1382972

S2546
Mitochondrial outer membrane protein SLC25A46

1

0

High-throughput

0.279

Low

1408247

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

0

High-throughput

0.279

Low

1411651

ADPGK
ADP-dependent glucokinase

1

0

High-throughput

0.279

Low

1411851

ZNG1A
Zinc-regulated GTPase metalloprotein activator 1A

1

0

High-throughput

0.279

Low

1415281

PTSS2
Phosphatidylserine synthase 2

1

0

High-throughput

0.279

Low

1416339

CHID1
Chitinase domain-containing protein 1

1

0

High-throughput

0.279

Low

1430887

METL9
Protein-L-histidine N-pros-methyltransferase

1

0

High-throughput

0.279

Low

1434533

HEAT1
HEAT repeat-containing protein 1

1

0

High-throughput

0.279

Low

1434706

TFB2M
Dimethyladenosine transferase 2, mitochondrial

1

0

High-throughput

0.279

Low

1438540

TPC
Mitochondrial thiamine pyrophosphate carrier

1

0

High-throughput

0.279

Low

1449391

FIRRM
FIGNL1-interacting regulator of recombination and mitosis

1

0

High-throughput

0.279

Low

1458486

GPN3
GPN-loop GTPase 3

1

0

High-throughput

0.279

Low

517269

AMY1B
Alpha-amylase 1B

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025