Protein: FEZ2
Fasciculation and elongation protein zeta-2 (Zygin II) (Zygin-2)

Gene: FEZ2
Organism: Homo sapiens
Interactions: 48
UniProt ID: Q9UHY8

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0007165 - signal transduction
GO:0007399 - nervous system development
GO:0007411 - axon guidance
GO:0030424 - axon

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1252043

KIF6
Kinesin-like protein KIF6

3

4

High-throughput

0.667

High

1460145

SCOC
Short coiled-coil protein

5

3

Small-scale

0.656

High

1400376

NEK1
Serine/threonine-protein kinase Nek1

1

1

Small-scale

0.552

High

1307671

ZDH17
Palmitoyltransferase ZDHHC17

1

1

High-throughput

0.532

High

246177

KIF1B
Kinesin-like protein KIF1B

1

3

High-throughput

0.515

High

844064

HD
Huntingtin

1

1

High-throughput

0.515

High

1417089

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

3

High-throughput

0.515

High

208092

TTI1
TELO2-interacting protein 1 homolog

1

0

High-throughput

0.513

High

849418

RANG
Ran-specific GTPase-activating protein

1

0

High-throughput

0.513

High

1123859

DCTN1
Dynactin subunit 1

1

0

High-throughput

0.511

High

243226

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.493

High

423409

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.493

High

791810

SYUA
Alpha-synuclein

1

0

High-throughput

0.493

High

896920

DYN2
Dynamin-2

1

0

High-throughput

0.493

High

927164

ATX3
Ataxin-3

1

0

High-throughput

0.493

High

927599

ATX1
Ataxin-1

1

0

High-throughput

0.493

High

954637

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.493

High

1160610

SMN
Survival motor neuron protein

1

0

High-throughput

0.493

High

270990

CLAP2
CLIP-associating protein 2

1

1

Small-scale

0.481

High

1271954

TEDC2
Tubulin epsilon and delta complex protein 2

1

1

Small-scale

0.481

High

1311658

KIBRA
Protein KIBRA

1

1

Small-scale

0.481

High

1406434

FEZ1
Fasciculation and elongation protein zeta-1

1

1

Small-scale

0.481

High

1051334

KPCZ
Protein kinase C zeta type

1

2

Small-scale

0.479

High

389894

TTHY
Transthyretin

1

1

High-throughput

0.470

High

911149

IMA1
Importin subunit alpha-1

1

0

High-throughput

0.460

High

1114585

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1396854

SNX27
Sorting nexin-27

1

0

High-throughput

0.458

High

1435416

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1460144

XPO7
Exportin-7

1

0

High-throughput

0.458

High

342357

BRD1
Bromodomain-containing protein 1

1

1

Small-scale

0.439

High

1133368

NC2A
Dr1-associated corepressor

1

1

Small-scale

0.439

High

1139415

RB3GP
Rab3 GTPase-activating protein catalytic subunit

1

1

Small-scale

0.439

High

1187145

TBC25
TBC1 domain family member 25

1

1

Small-scale

0.439

High

1288391

TLK2
Serine/threonine-protein kinase tousled-like 2

1

1

Small-scale

0.439

High

1331136

PDCD7
Programmed cell death protein 7

1

1

Small-scale

0.439

High

1411134

ZN251
Zinc finger protein 251

1

1

Small-scale

0.439

High

1437568

SP30L
Histone deacetylase complex subunit SAP30L

1

1

Small-scale

0.439

High

1453793

RAI14
Ankycorbin

1

2

Small-scale

0.439

High

1460146

SMC3
Structural maintenance of chromosomes protein 3

1

1

Small-scale

0.439

High

290998

PPM1B
Protein phosphatase 1B

2

0

High-throughput

0.328

High

1316071

TRM2A
tRNA

2

0

High-throughput

0.328

High

1460147

RT07
Small ribosomal subunit protein uS7m

2

0

High-throughput

0.328

High

341162

DIRA3
GTP-binding protein Di-Ras3

2

0

High-throughput

0.318

High

66817

C2C4B
C2 calcium-dependent domain-containing protein 4B

1

0

High-throughput

0.279

Low

273792

ATS4
A disintegrin and metalloproteinase with thrombospondin motifs 4

1

0

High-throughput

0.279

Low

301751

WFS1
Wolframin

1

0

High-throughput

0.268

Low

890070

PSN1
Presenilin-1

1

0

High-throughput

0.268

Low

731681

STIP1
Stress-induced-phosphoprotein 1

1

0

Small-scale

0.251

Low


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Last updated: 11Aug2025