Protein: TTI1
TELO2-interacting protein 1 homolog (Protein SMG10)

Gene: TTI1
Organism: Homo sapiens
Interactions: 108
UniProt ID: O43156

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0031931 - TORC1 complex
GO:0031932 - TORC2 complex
GO:0032006 - regulation of TOR signaling

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

208096

RUVB2
RuvB-like 2

5

6

Small-scale

0.720

High

208103

TELO2
Telomere length regulation protein TEL2 homolog

5

3

Small-scale

0.718

High

208097

RUVB1
RuvB-like 1

4

6

Small-scale

0.697

High

208029

MTOR
Serine/threonine-protein kinase mTOR

4

16

Small-scale

0.686

High

208043

ATM
Serine-protein kinase ATM

3

16

Small-scale

0.677

High

208055

TTI2
TELO2-interacting protein 2

4

0

Small-scale

0.673

High

208079

SMG1
Serine/threonine-protein kinase SMG1

3

16

Small-scale

0.671

High

208039

PRKDC
DNA-dependent protein kinase catalytic subunit

3

16

Small-scale

0.667

High

208102

TRRAP
Transformation/transcription domain-associated protein

3

16

Small-scale

0.667

High

208005

SCN2B
Sodium channel regulatory subunit beta-2

4

2

High-throughput

0.630

High

208045

ATR
Serine/threonine-protein kinase ATR

2

16

Small-scale

0.621

High

208076

VSIG2
V-set and immunoglobulin domain-containing protein 2

3

1

High-throughput

0.609

High

208088

PD1L1
Programmed cell death 1 ligand 1

3

1

High-throughput

0.609

High

208015

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

2

0

Small-scale

0.608

High

208065

VSIG1
V-set and immunoglobulin domain-containing protein 1

3

2

High-throughput

0.604

High

208087

PIHD1
PIH1 domain-containing protein 1

2

0

Small-scale

0.602

High

208018

FPR1
fMet-Leu-Phe receptor

2

3

High-throughput

0.601

High

208026

HSP74
Heat shock 70 kDa protein 4

2

1

Small-scale

0.584

High

208042

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

2

5

High-throughput

0.549

High

208063

P2RY8
S-geranylgeranyl-glutathione receptor P2RY8

2

5

High-throughput

0.549

High

208019

FPR2
N-formyl peptide receptor 2

1

3

High-throughput

0.536

High

208040

EFNB1
Ephrin-B1

1

2

High-throughput

0.536

High

208083

RPAP3
RNA polymerase II-associated protein 3

1

1

Small-scale

0.536

High

208094

FBX9
F-box only protein 9

1

0

Small-scale

0.530

High

62859

POTEF
POTE ankyrin domain family member F

1

0

High-throughput

0.513

High

208007

RMP
Unconventional prefoldin RPB5 interactor 1

1

0

Small-scale

0.513

High

208012

TACD2
Tumor-associated calcium signal transducer 2

1

0

High-throughput

0.513

High

208014

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.513

High

208017

S1PR1
Sphingosine 1-phosphate receptor 1

1

0

High-throughput

0.513

High

208033

IRAK1
Interleukin-1 receptor-associated kinase 1

1

0

High-throughput

0.513

High

208047

HERC1
Probable E3 ubiquitin-protein ligase HERC1

1

0

High-throughput

0.513

High

208050

AGK
Acylglycerol kinase, mitochondrial

1

0

High-throughput

0.513

High

208058

RICTR
Rapamycin-insensitive companion of mTOR

1

0

Small-scale

0.513

High

208066

RPTOR
Regulatory-associated protein of mTOR

1

0

Small-scale

0.513

High

208074

PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1

1

0

High-throughput

0.513

High

208092

FEZ2
Fasciculation and elongation protein zeta-2

1

0

High-throughput

0.513

High

208072

RL3R2
Relaxin-3 receptor 2

1

5

High-throughput

0.494

High

133218

P2Y10
Putative P2Y purinoceptor 10

1

6

High-throughput

0.489

High

165865

FFAR1
Free fatty acid receptor 1

1

6

High-throughput

0.489

High

182417

GP182
G-protein coupled receptor 182

1

5

High-throughput

0.489

High

208034

EFNA4
Ephrin-A4

1

2

High-throughput

0.489

High

208035

EFNA5
Ephrin-A5

1

2

High-throughput

0.489

High

208037

PAR2
Proteinase-activated receptor 2

1

5

High-throughput

0.489

High

208069

PKR1
Prokineticin receptor 1

1

1

High-throughput

0.489

High

208101

GPR55
G-protein coupled receptor 55

1

7

High-throughput

0.489

High

208105

GPR45
Probable G-protein coupled receptor 45

1

2

High-throughput

0.489

High

208038

SUMO2
Small ubiquitin-related modifier 2

1

0

High-throughput

0.480

High

208006

TP4A3
Protein tyrosine phosphatase type IVA 3

1

0

High-throughput

0.458

High

208008

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.458

High

208022

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

208028

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

208032

RL14
Large ribosomal subunit protein eL14

1

0

High-throughput

0.458

High

208041

PO5F1
POU domain, class 5, transcription factor 1

1

0

High-throughput

0.458

High

208044

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

0

High-throughput

0.458

High

208046

CUL3
Cullin-3

1

0

High-throughput

0.458

High

208053

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

208059

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

208060

TBA1A
Tubulin alpha-1A chain

1

0

Small-scale

0.458

High

208061

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

208075

MOB3A
MOB kinase activator 3A

1

0

High-throughput

0.458

High

208082

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

208084

FBX6
F-box only protein 6

1

0

High-throughput

0.458

High

208090

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

208095

MACF1
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5

1

0

High-throughput

0.458

High

208104

RBM8A
RNA-binding protein 8A

1

0

Small-scale

0.458

High

208030

LPAR6
Lysophosphatidic acid receptor 6

1

5

High-throughput

0.437

High

208051

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

171362

S27A2
Long-chain fatty acid transport protein 2

1

3

High-throughput

0.407

High

208027

APJ
Apelin receptor

1

1

High-throughput

0.407

High

208054

S35E4
Solute carrier family 35 member E4

1

1

High-throughput

0.407

High

208056

S27A4
Long-chain fatty acid transport protein 4

1

3

High-throughput

0.407

High

208057

S27A1
Long-chain fatty acid transport protein 1

1

3

High-throughput

0.407

High

208098

VSIG4
V-set and immunoglobulin domain-containing protein 4

1

2

High-throughput

0.407

High

208100

S27A6
Long-chain fatty acid transport protein 6

1

3

High-throughput

0.407

High

208025

CD68
Macrosialin

4

0

High-throughput

0.360

High

208086

TMM51
Transmembrane protein 51

3

0

High-throughput

0.347

High

208068

SIGL1
SIGLEC family-like protein 1

3

0

High-throughput

0.345

High

208016

ACM3
Muscarinic acetylcholine receptor M3

2

0

High-throughput

0.328

High

208024

CD70
CD70 antigen

2

0

High-throughput

0.328

High

208049

AR13B
ADP-ribosylation factor-like protein 13B

2

0

High-throughput

0.318

High

208009

GLPA
Glycophorin-A

2

0

High-throughput

0.313

High

208020

TNR5
Tumor necrosis factor receptor superfamily member 5

2

0

High-throughput

0.313

High

208021

STOM
Stomatin

1

0

High-throughput

0.279

Low

208023

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

0

High-throughput

0.279

Low

208036

ARSF
Arylsulfatase F

1

0

High-throughput

0.279

Low

208062

CMTD1
Catechol O-methyltransferase domain-containing protein 1

1

0

High-throughput

0.279

Low

208064

HTR5A
HEAT repeat-containing protein 5A

1

0

High-throughput

0.279

Low

208067

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.279

Low

208071

HUMMR
Protein MGARP

1

0

High-throughput

0.279

Low

208073

NICA
Nicastrin

1

0

High-throughput

0.279

Low

208078

CCD42
Coiled-coil domain-containing protein 42

1

0

High-throughput

0.279

Low

208080

F234A
Protein FAM234A

1

0

High-throughput

0.279

Low

208081

KLK15
Kallikrein-15

1

0

High-throughput

0.279

Low

208089

CCG4
Voltage-dependent calcium channel gamma-4 subunit

1

0

High-throughput

0.279

Low

208093

CC018
Uncharacterized protein C3orf18

1

0

High-throughput

0.279

Low

208099

B3GT5
Beta-1,3-galactosyltransferase 5

1

0

High-throughput

0.279

Low

208106

NPTN
Neuroplastin

1

0

High-throughput

0.279

Low

208004

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.249

Low

208010

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

208011

CLCB
Clathrin light chain B

1

0

High-throughput

0.249

Low

208013

PTPRF
Receptor-type tyrosine-protein phosphatase F

1

0

High-throughput

0.249

Low

208031

5HT6R
5-hydroxytryptamine receptor 6

1

0

Small-scale

0.249

Low

208048

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low

208085

TMPS4
Transmembrane protease serine 4

1

0

High-throughput

0.249

Low

208091

ZNHI2
Zinc finger HIT domain-containing protein 2

1

0

High-throughput

0.249

Low

208052

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.232

Low

208070

MO2R1
Cell surface glycoprotein CD200 receptor 1

1

0

High-throughput

0.232

Low

208077

S35E1
Solute carrier family 35 member E1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025