Protein: TBKB1
TANK-binding kinase 1-binding protein 1 (TBK1-binding protein 1)

Gene: TBKB1, TBKBP1
Organism: Homo sapiens
Interactions: 75
UniProt ID: A7MCY6

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0008270 - zinc ion binding
GO:0051607 - defense response to virus
GO:0060337 - type I interferon-mediated signaling pathway
GO:1902554 - serine/threonine protein kinase complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

67808

TBK1
Serine/threonine-protein kinase TBK1

10

7

Small-scale

0.757

High

67766

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

6

8

Small-scale

0.736

High

67769

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

4

7

Small-scale

0.697

High

67787

RBCC1
RB1-inducible coiled-coil protein 1

3

7

Small-scale

0.685

High

67747

APBA3
Amyloid-beta A4 precursor protein-binding family A member 3

1

6

High-throughput

0.586

High

67810

AGO2
Protein argonaute-2

1

1

High-throughput

0.586

High

67777

DPPA3
Developmental pluripotency-associated protein 3

2

0

High-throughput

0.585

High

67755

PIP
Prolactin-inducible protein

2

1

High-throughput

0.549

High

67744

OBSL1
Obscurin-like protein 1

1

9

High-throughput

0.536

High

67756

MIF
Macrophage migration inhibitory factor

1

2

High-throughput

0.536

High

67762

FXR2
RNA-binding protein FXR2

1

5

High-throughput

0.536

High

67765

FMR1
Fragile X messenger ribonucleoprotein 1

1

5

High-throughput

0.536

High

67795

RBM14
RNA-binding protein 14

1

3

High-throughput

0.536

High

67800

EGLN3
Prolyl hydroxylase EGLN3

1

2

High-throughput

0.536

High

67741

TBKB1
TANK-binding kinase 1-binding protein 1

1

17

Small-scale

0.515

High

67780

ACD11
Acyl-CoA dehydrogenase family member 11

1

0

High-throughput

0.513

High

67802

PICK1
PRKCA-binding protein

1

0

High-throughput

0.513

High

67757

CSK22
Casein kinase II subunit alpha'

1

6

High-throughput

0.489

High

67813

ANGP4
Angiopoietin-4

1

1

High-throughput

0.489

High

67745

KLHL2
Kelch-like protein 2

1

3

Small-scale

0.481

High

67752

TBB5
Tubulin beta chain

1

1

Small-scale

0.481

High

67764

ACTG
Actin, cytoplasmic 2

1

1

Small-scale

0.481

High

67812

CTND2
Catenin delta-2

1

2

Small-scale

0.481

High

67746

KI20A
Kinesin-like protein KIF20A

1

10

High-throughput

0.479

High

67748

EGFR
Epidermal growth factor receptor

1

7

High-throughput

0.479

High

67750

P53
Cellular tumor antigen p53

1

1

High-throughput

0.479

High

67751

K2C8
Keratin, type II cytoskeletal 8

1

4

High-throughput

0.479

High

67758

TTP
mRNA decay activator protein ZFP36

1

2

High-throughput

0.479

High

67759

PERI
Peripherin

1

8

High-throughput

0.479

High

67761

MCM2
DNA replication licensing factor MCM2

1

3

High-throughput

0.479

High

67768

CUL3
Cullin-3

1

7

High-throughput

0.479

High

67775

A16L1
Autophagy-related protein 16-1

1

3

High-throughput

0.479

High

67778

SYNE3
Nesprin-3

1

3

High-throughput

0.479

High

67782

HOOK3
Protein Hook homolog 3

1

6

High-throughput

0.479

High

67784

RN214
RING finger protein 214

1

1

High-throughput

0.479

High

67786

COP1
E3 ubiquitin-protein ligase COP1

1

3

High-throughput

0.479

High

67793

CNO6L
CCR4-NOT transcription complex subunit 6-like

1

2

High-throughput

0.479

High

67794

CI072
Guanine nucleotide exchange factor C9orf72

1

1

Small-scale

0.479

High

67798

UNK
RING finger protein unkempt homolog

1

3

High-throughput

0.479

High

67799

AZI2
5-azacytidine-induced protein 2

1

5

Small-scale

0.479

High

67803

LATS2
Serine/threonine-protein kinase LATS2

1

5

High-throughput

0.479

High

67805

WHRN
Whirlin

1

5

High-throughput

0.479

High

67807

ANFY1
Rabankyrin-5

1

6

High-throughput

0.479

High

67809

XPO7
Exportin-7

1

3

High-throughput

0.479

High

67763

IRAK1
Interleukin-1 receptor-associated kinase 1

1

0

Small-scale

0.460

High

67767

DCTN2
Dynactin subunit 2

1

0

High-throughput

0.458

High

67772

ACBD5
Acyl-CoA-binding domain-containing protein 5

1

0

High-throughput

0.458

High

67773

OBI1
ORC ubiquitin ligase 1

1

0

High-throughput

0.458

High

67779

MEX3B
RNA-binding protein MEX3B

1

0

High-throughput

0.458

High

67814

MARF1
Meiosis regulator and mRNA stability factor 1

1

0

High-throughput

0.458

High

67806

ABI3
ABI gene family member 3

1

18

High-throughput

0.445

High

67743

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

1

6

High-throughput

0.437

High

67749

TNFA
Tumor necrosis factor

1

2

Small-scale

0.437

High

67753

K1C19
Keratin, type I cytoskeletal 19

1

1

High-throughput

0.437

High

67760

PAXI
Paxillin

1

12

High-throughput

0.437

High

67774

CP135
Centrosomal protein of 135 kDa

1

5

High-throughput

0.437

High

67776

LTOR1
Ragulator complex protein LAMTOR1

1

3

High-throughput

0.437

High

67781

PATL1
Protein PAT1 homolog 1

1

4

High-throughput

0.437

High

67783

NIN
Ninein

1

7

High-throughput

0.437

High

67785

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

6

High-throughput

0.437

High

67788

PARD3
Partitioning defective 3 homolog

1

5

High-throughput

0.437

High

67790

VP33A
Vacuolar protein sorting-associated protein 33A

1

2

High-throughput

0.437

High

67791

BICD1
Protein bicaudal D homolog 1

1

9

High-throughput

0.437

High

67796

LZTS2
Leucine zipper putative tumor suppressor 2

1

10

High-throughput

0.437

High

67797

CP250
Centrosome-associated protein CEP250

1

2

High-throughput

0.437

High

67801

TNR6C
Trinucleotide repeat-containing gene 6C protein

1

8

High-throughput

0.437

High

67804

SEP10
Septin-10

1

7

High-throughput

0.437

High

67811

TNR6B
Trinucleotide repeat-containing gene 6B protein

1

5

High-throughput

0.437

High

67770

CF184
Cilia- and flagella-associated protein 184

1

0

High-throughput

0.279

Low

67742

GRRE1
Granule associated Rac and RHOG effector protein 1

1

0

High-throughput

0.249

Low

67771

SMAG2
Protein Smaug homolog 2

1

0

High-throughput

0.249

Low

67789

DCAF4
DDB1- and CUL4-associated factor 4

1

0

High-throughput

0.249

Low

67792

BORC6
BLOC-1-related complex subunit 6

1

0

High-throughput

0.249

Low

67754

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025