Protein: SMS
Somatostatin (Growth hormone release-inhibiting factor) [Cleaved into: Somatostatin-28; Somatostatin-14 (SST-14); Neuronostatin (NST)]

Gene: SMS, SST
Organism: Homo sapiens
Interactions: 41
UniProt ID: P61278

Gene Ontology (top 5):
GO:0005179 - hormone activity
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005829 - cytosol
GO:0006972 - hyperosmotic response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

421842

A4
Amyloid-beta precursor protein

2

0

Small-scale

0.606

High

420464

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

2

Small-scale

0.500

High

744458

SSR3
Somatostatin receptor type 3

1

0

Small-scale

0.500

High

960362

SMS
Somatostatin

1

0

Small-scale

0.480

High

539531

PYGB
Glycogen phosphorylase, brain form

1

1

Small-scale

0.445

High

539590

PYGM
Glycogen phosphorylase, muscle form

1

1

Small-scale

0.445

High

960337

STX1B
Syntaxin-1B

1

1

Small-scale

0.445

High

960365

AT2B2
Plasma membrane calcium-transporting ATPase 2

1

1

Small-scale

0.445

High

960370

STX1A
Syntaxin-1A

1

1

Small-scale

0.445

High

123364

BACH
Cytosolic acyl coenzyme A thioester hydrolase

1

0

Small-scale

0.426

High

142320

PEX7
Peroxisomal targeting signal 2 receptor

1

0

High-throughput

0.426

High

482597

GNAO
Guanine nucleotide-binding protein G(o) subunit alpha

1

0

Small-scale

0.426

High

800473

VATA
V-type proton ATPase catalytic subunit A

1

0

Small-scale

0.426

High

844919

EAA2
Excitatory amino acid transporter 2

1

0

Small-scale

0.426

High

910288

6PGD
6-phosphogluconate dehydrogenase, decarboxylating

1

0

Small-scale

0.426

High

954381

SNP25
Synaptosomal-associated protein 25

1

0

Small-scale

0.426

High

960363

PFD3
Prefoldin subunit 3

1

0

Small-scale

0.426

High

960366

PP2BA
Protein phosphatase 3 catalytic subunit alpha

1

0

Small-scale

0.426

High

960371

DECR
2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial

1

0

Small-scale

0.426

High

960372

SV2A
Synaptic vesicle glycoprotein 2A

1

0

Small-scale

0.426

High

960373

CNRP1
CB1 cannabinoid receptor-interacting protein 1

1

0

Small-scale

0.426

High

960374

GAB2
GRB2-associated-binding protein 2

1

0

High-throughput

0.426

High

960376

X6RFL8
Ras-related protein Rab-14

1

0

Small-scale

0.426

High

72956

B1AKY9
Sodium/potassium-transporting ATPase subunit alpha

1

2

Small-scale

0.407

High

117822

M0R116
Sodium/potassium-transporting ATPase subunit alpha

1

2

Small-scale

0.407

High

292110

S2512
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial

1

3

Small-scale

0.407

High

424843

ADT2
ADP/ATP translocase 2

1

3

Small-scale

0.407

High

551981

ADT1
ADP/ATP translocase 1

1

3

Small-scale

0.407

High

552184

ADT3
ADP/ATP translocase 3

1

3

Small-scale

0.407

High

627300

AT2B1
Plasma membrane calcium-transporting ATPase 1

1

3

Small-scale

0.407

High

960364

S25A3
Solute carrier family 25 member 3

1

4

Small-scale

0.407

High

960367

PDIA2
Protein disulfide-isomerase A2

1

0

Small-scale

0.261

Low

420781

AT1B1
Sodium/potassium-transporting ATPase subunit beta-1

1

0

Small-scale

0.249

Low

96910

E9PE24
Visinin-like protein 1

1

0

Small-scale

0.232

Low

104674

F6U1T9
Protein phosphatase 3 regulatory subunit B, alpha

1

0

Small-scale

0.232

Low

117027

J3KQA0
Synaptotagmin

1

0

Small-scale

0.232

Low

423892

ALDH2
Aldehyde dehydrogenase, mitochondrial

1

0

Small-scale

0.232

Low

960368

RM49
Large ribosomal subunit protein mL49

1

0

High-throughput

0.232

Low

960369

LAGE3
EKC/KEOPS complex subunit LAGE3

1

0

High-throughput

0.232

Low

960375

PCDG9
Protocadherin gamma-A9

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025