Protein: TM63C
Osmosensitive cation channel TMEM63C (Calcium permeable stress-gated cation channel 1) (Transmembrane protein 63C) (hTMEM63C)

Gene: TM63C, TMEM63C
Organism: Homo sapiens
Interactions: 33
UniProt ID: Q9P1W3

Gene Ontology (top 5):
GO:0003094 - glomerular filtration
GO:0005227 - calcium-activated cation channel activity
GO:0005765 - lysosomal membrane
GO:0005789 - endoplasmic reticulum membrane
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

320512

TM63A
Mechanosensitive cation channel TMEM63A

1

6

High-throughput

0.691

High

1212317

TM63B
Mechanosensitive cation channel TMEM63B

1

6

High-throughput

0.691

High

609826

LEG3
Galectin-3

1

6

High-throughput

0.536

High

1126379

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

1

High-throughput

0.536

High

1208117

RNFT1
E3 ubiquitin-protein ligase RNFT1

1

1

High-throughput

0.536

High

1327991

CISD2
CDGSH iron-sulfur domain-containing protein 2

1

1

High-throughput

0.536

High

1385210

SARAF
Store-operated calcium entry-associated regulatory factor

1

2

High-throughput

0.536

High

1428169

YIPF3
Protein YIPF3

1

1

High-throughput

0.536

High

1436054

DJC18
DnaJ homolog subfamily C member 18

1

1

High-throughput

0.536

High

189890

STX7
Syntaxin-7

1

0

High-throughput

0.513

High

248635

FADS1
Acyl-CoA

1

0

High-throughput

0.513

High

643403

OSBP1
Oxysterol-binding protein 1

1

0

High-throughput

0.513

High

956797

RAB10
Ras-related protein Rab-10

1

0

High-throughput

0.513

High

1103803

PLD1
Phospholipase D1

1

0

High-throughput

0.513

High

1154773

VAMP3
Vesicle-associated membrane protein 3

1

0

High-throughput

0.513

High

1248684

LCLT1
Lysocardiolipin acyltransferase 1

1

0

High-throughput

0.513

High

1327065

VMA12
Vacuolar ATPase assembly protein VMA12

1

0

High-throughput

0.513

High

1352385

RHBL4
Rhomboid-related protein 4

1

0

High-throughput

0.513

High

1454157

ERG28
Ergosterol biosynthetic protein 28 homolog

1

0

High-throughput

0.513

High

1454158

STX8
Syntaxin-8

1

0

High-throughput

0.513

High

1454159

TMX2
Thioredoxin-related transmembrane protein 2

1

0

High-throughput

0.513

High

1454160

SNX14
Sorting nexin-14

1

0

High-throughput

0.513

High

1239560

ZNT6
Zinc transporter 6

1

5

High-throughput

0.489

High

1449771

ZDH18
Palmitoyltransferase ZDHHC18

1

1

High-throughput

0.489

High

1453955

RN181
E3 ubiquitin-protein ligase RNF181

1

1

High-throughput

0.489

High

506679

GPHRB
Golgi pH regulator B

1

2

High-throughput

0.437

High

85412

GPHRA
Golgi pH regulator A

1

2

High-throughput

0.407

High

328408

NDUB8
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial

1

0

High-throughput

0.279

Low

377008

ANF
Natriuretic peptides A

1

0

High-throughput

0.279

Low

1231422

ZN787
Zinc finger protein 787

1

0

High-throughput

0.279

Low

1327886

MINY1
Ubiquitin carboxyl-terminal hydrolase MINDY-1

1

0

High-throughput

0.279

Low

1331205

F241A
Uncharacterized protein FAM241A

1

0

High-throughput

0.279

Low

1399181

VMA22
Vacuolar ATPase assembly protein VMA22

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025