Protein: RNFT1
E3 ubiquitin-protein ligase RNFT1 (EC 2.3.2.27) (Protein PTD016) (RING finger and transmembrane domain-containing protein 1)

Gene: RNFT1
Organism: Homo sapiens
Interactions: 34
UniProt ID: Q5M7Z0

Gene Ontology (top 5):
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0008270 - zinc ion binding
GO:0043130 - ubiquitin binding
GO:0051865 - protein autoubiquitination

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

957090

UB2D3
Ubiquitin-conjugating enzyme E2 D3

1

20

Small-scale

0.647

High

1208105

RNFT1
E3 ubiquitin-protein ligase RNFT1

1

16

Small-scale

0.647

High

1027032

REEP5
Receptor expression-enhancing protein 5

2

1

High-throughput

0.628

High

1208106

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

20

High-throughput

0.625

High

982201

UB2D2
Ubiquitin-conjugating enzyme E2 D2

1

20

High-throughput

0.590

High

1208116

I17RB
Interleukin-17 receptor B

2

1

High-throughput

0.574

High

595055

KCNA2
Potassium voltage-gated channel subfamily A member 2

1

3

High-throughput

0.536

High

1208112

ZDH12
Palmitoyltransferase ZDHHC12

1

7

High-throughput

0.536

High

1208117

TM63C
Osmosensitive cation channel TMEM63C

1

1

High-throughput

0.536

High

1208111

M4A15
Membrane-spanning 4-domains subfamily A member 15

1

1

High-throughput

0.489

High

1208113

ZNT2
Proton-coupled zinc antiporter SLC30A2

1

11

High-throughput

0.489

High

1208118

PCD10
Protocadherin-10

1

6

High-throughput

0.489

High

360009

NB5R3
NADH-cytochrome b5 reductase 3

1

1

High-throughput

0.479

High

1127835

ERG1
Squalene monooxygenase

1

1

High-throughput

0.479

High

1208109

MARH3
E3 ubiquitin-protein ligase MARCHF3

1

2

High-throughput

0.479

High

1208114

RNF26
E3 ubiquitin-protein ligase RNF26

1

2

High-throughput

0.479

High

156284

G3PT
Glyceraldehyde-3-phosphate dehydrogenase, testis-specific

1

5

High-throughput

0.470

High

934216

BI1
Bax inhibitor 1

1

0

High-throughput

0.458

High

1208110

ZNT8
Proton-coupled zinc antiporter SLC30A8

1

11

High-throughput

0.445

High

218278

TGON2
Trans-Golgi network integral membrane protein 2

1

3

High-throughput

0.437

High

592848

CBR1
Carbonyl reductase [NADPH] 1

1

5

High-throughput

0.437

High

722720

AL1B1
Aldehyde dehydrogenase X, mitochondrial

1

2

High-throughput

0.437

High

877339

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

1

High-throughput

0.437

High

884756

SYSC
Serine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.437

High

887670

PSB2
Proteasome subunit beta type-2

1

20

High-throughput

0.437

High

1163996

HCDH
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial

1

1

High-throughput

0.437

High

1208108

ABHDD
Protein ABHD13

1

1

High-throughput

0.437

High

1208119

VPP2
V-type proton ATPase 116 kDa subunit a 2

1

5

High-throughput

0.437

High

1157171

S15A2
Solute carrier family 15 member 2

1

2

High-throughput

0.407

High

317647

ATG12
Ubiquitin-like protein ATG12

1

0

High-throughput

0.249

Low

944492

GEMI4
Gem-associated protein 4

1

0

High-throughput

0.249

Low

1208107

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.249

Low

1208115

EXOS3
Exosome complex component RRP40

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025