Protein: TTL12
Tubulin--tyrosine ligase-like protein 12 (Inactive tubulin--tyrosine ligase-like protein 12)

Gene: TTL12, TTLL12
Organism: Homo sapiens
Interactions: 92
UniProt ID: Q14166

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005813 - centrosome
GO:0005819 - spindle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

679158

DNJB1
DnaJ homolog subfamily B member 1

6

4

High-throughput

0.737

High

1051750

EF1A2
Elongation factor 1-alpha 2

5

5

High-throughput

0.716

High

1122705

DNJB4
DnaJ homolog subfamily B member 4

5

4

High-throughput

0.712

High

996143

EF1A1
Elongation factor 1-alpha 1

4

5

High-throughput

0.698

High

457434

TBB5
Tubulin beta chain

1

1

High-throughput

0.618

High

1122669

DHX57
Putative ATP-dependent RNA helicase DHX57

2

0

High-throughput

0.602

High

1122681

EFMT1
EEF1A lysine methyltransferase 1

2

0

High-throughput

0.602

High

241657

PRKN
E3 ubiquitin-protein ligase parkin

2

2

High-throughput

0.584

High

1122675

SH2D3
SH2 domain-containing protein 3C

2

0

High-throughput

0.547

High

274574

DNJB6
DnaJ homolog subfamily B member 6

1

4

High-throughput

0.536

High

966306

1433G
14-3-3 protein gamma

1

4

High-throughput

0.536

High

1122687

OPTN
Optineurin

1

3

High-throughput

0.536

High

1122708

NTNG1
Netrin-G1

1

5

High-throughput

0.536

High

1122689

LCOR
Ligand-dependent corepressor

1

0

High-throughput

0.518

High

155109

SOCS2
Suppressor of cytokine signaling 2

1

1

High-throughput

0.515

High

156040

SOCS6
Suppressor of cytokine signaling 6

1

1

High-throughput

0.515

High

389356

FINC
Fibronectin

1

0

High-throughput

0.513

High

611860

RL35A
Large ribosomal subunit protein eL33

1

0

High-throughput

0.513

High

733348

CCR1
C-C chemokine receptor type 1

1

0

High-throughput

0.513

High

1122677

UBP32
Ubiquitin carboxyl-terminal hydrolase 32

1

0

High-throughput

0.513

High

1122684

GGH
Gamma-glutamyl hydrolase

1

0

High-throughput

0.513

High

1122686

EFMT3
EEF1A lysine methyltransferase 3

1

0

High-throughput

0.513

High

1122700

ANLN
Anillin

1

0

High-throughput

0.513

High

1122710

WIF1
Wnt inhibitory factor 1

1

3

High-throughput

0.489

High

625376

CSK22
Casein kinase II subunit alpha'

1

3

High-throughput

0.481

High

964275

SUMO2
Small ubiquitin-related modifier 2

1

0

High-throughput

0.480

High

142990

NFIB
Nuclear factor 1 B-type

1

1

High-throughput

0.479

High

289996

OFD1
Centriole and centriolar satellite protein OFD1

1

1

High-throughput

0.479

High

413816

P53
Cellular tumor antigen p53

1

4

High-throughput

0.479

High

473980

NFIC
Nuclear factor 1 C-type

1

1

High-throughput

0.479

High

520035

ANDR
Androgen receptor

1

1

High-throughput

0.479

High

588674

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

695434

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

731284

STIP1
Stress-induced-phosphoprotein 1

1

1

High-throughput

0.479

High

891540

GSK3B
Glycogen synthase kinase-3 beta

1

4

High-throughput

0.479

High

1122671

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.479

High

1122673

CNTRL
Centriolin

1

2

High-throughput

0.479

High

1122679

FBF1
Fas-binding factor 1

1

3

High-throughput

0.479

High

1122692

FSD1
Fibronectin type III and SPRY domain-containing protein 1

1

3

High-throughput

0.479

High

1122698

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.479

High

1122699

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.479

High

184291

NPHP1
Nephrocystin-1

1

0

High-throughput

0.458

High

345805

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

380027

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.458

High

400822

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

411914

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.458

High

565381

ITA4
Integrin alpha-4

1

0

High-throughput

0.458

High

768168

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

964940

WDR5
WD repeat-containing protein 5

1

0

High-throughput

0.458

High

986419

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

0

High-throughput

0.458

High

1041061

CAV1
Caveolin-1

1

0

High-throughput

0.458

High

1122480

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

0

High-throughput

0.458

High

1122666

FSCN1
Fascin

1

0

High-throughput

0.458

High

1122668

RN123
E3 ubiquitin-protein ligase RNF123

1

0

High-throughput

0.458

High

1122670

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

1122672

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1122676

POC5
Centrosomal protein POC5

1

0

High-throughput

0.458

High

1122678

SAP25
Histone deacetylase complex subunit SAP25

1

0

Small-scale

0.458

High

1122683

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

1122685

FBX32
F-box only protein 32

1

0

High-throughput

0.458

High

1122691

NECD
Necdin

1

0

High-throughput

0.458

High

1122694

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.458

High

1122696

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

0

High-throughput

0.458

High

1122697

ATG5
Autophagy protein 5

1

0

High-throughput

0.458

High

1122702

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

0

High-throughput

0.458

High

1122706

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

142338

PEX7
Peroxisomal targeting signal 2 receptor

1

1

High-throughput

0.445

High

619791

VCAM1
Vascular cell adhesion protein 1

1

1

High-throughput

0.445

High

1122667

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

1

High-throughput

0.445

High

1122695

ZDHC5
Palmitoyltransferase ZDHHC5

1

2

High-throughput

0.445

High

1122703

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.438

High

261171

NSMA
Sphingomyelin phosphodiesterase 2

1

0

High-throughput

0.426

High

598734

ANFB
Natriuretic peptides B

1

0

High-throughput

0.426

High

664923

CRHBP
Corticotropin-releasing factor-binding protein

1

0

High-throughput

0.426

High

689825

CD27
CD27 antigen

1

0

High-throughput

0.426

High

1121394

KEAP1
Kelch-like ECH-associated protein 1

1

0

High-throughput

0.426

High

1122682

SNR27
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein

1

0

High-throughput

0.426

High

1122688

OTUB1
Ubiquitin thioesterase OTUB1

1

0

High-throughput

0.426

High

1122701

ITM2C
Integral membrane protein 2C

1

0

High-throughput

0.426

High

1122704

DDX28
Probable ATP-dependent RNA helicase DDX28

1

0

High-throughput

0.426

High

1122709

PCDG9
Protocadherin gamma-A9

1

0

High-throughput

0.426

High

330150

VENTX
Homeobox protein VENTX

1

2

High-throughput

0.407

High

1122690

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

1

3

High-throughput

0.407

High

886850

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.391

High

1122693

PBDC1
Protein PBDC1

3

0

High-throughput

0.347

High

506724

PRR35
Proline-rich protein 35

2

0

High-throughput

0.316

High

1122680

F222B
Protein FAM222B

2

0

High-throughput

0.316

High

105919

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

1122707

NUP50
Nuclear pore complex protein Nup50

1

0

High-throughput

0.249

Low

628618

CAP7
Azurocidin

1

0

High-throughput

0.232

Low

1103957

RM49
Large ribosomal subunit protein mL49

1

0

High-throughput

0.232

Low

1122674

SLX4
Structure-specific endonuclease subunit SLX4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025