Protein: WIF1
Wnt inhibitory factor 1 (WIF-1)

Gene: WIF1
Organism: Homo sapiens
Interactions: 150
UniProt ID: Q9Y5W5

Gene Ontology (top 5):
GO:0005102 - signaling receptor binding
GO:0005576 - extracellular region
GO:0007165 - signal transduction
GO:0009986 - cell surface
GO:0016055 - Wnt signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1491752

JAM1
Junctional adhesion molecule A

1

14

High-throughput

0.618

High

950738

KR108
Keratin-associated protein 10-8

3

7

High-throughput

0.616

High

144117

WNT7A
Protein Wnt-7a

2

4

Small-scale

0.602

High

70548

CRTP1
Cysteine-rich tail protein 1

2

1

High-throughput

0.553

High

648754

FGFR4
Fibroblast growth factor receptor 4

1

10

High-throughput

0.541

High

171353

MYPT1
Protein phosphatase 1 regulatory subunit 12A

1

13

High-throughput

0.536

High

261677

CATL2
Cathepsin L2

1

1

High-throughput

0.536

High

343663

OXSR1
Serine/threonine-protein kinase OSR1

1

3

High-throughput

0.536

High

360153

NB5R3
NADH-cytochrome b5 reductase 3

1

1

High-throughput

0.536

High

821228

TXLNA
Alpha-taxilin

1

4

High-throughput

0.536

High

1038385

MP2K1
Dual specificity mitogen-activated protein kinase kinase 1

1

6

High-throughput

0.536

High

1107645

PICAL
Phosphatidylinositol-binding clathrin assembly protein

1

2

High-throughput

0.536

High

1150903

CIP4
Cdc42-interacting protein 4

1

1

High-throughput

0.536

High

1368317

STAM1
Signal transducing adapter molecule 1

1

2

High-throughput

0.536

High

1491346

TLN1
Talin-1

1

5

High-throughput

0.536

High

1491755

STK24
Serine/threonine-protein kinase 24

1

4

High-throughput

0.536

High

1491756

ICOS
Inducible T-cell costimulator

1

0

High-throughput

0.518

High

181471

PGRC2
Membrane-associated progesterone receptor component 2

1

0

High-throughput

0.513

High

1110863

ULA1
NEDD8-activating enzyme E1 regulatory subunit

1

0

High-throughput

0.513

High

1131717

2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

1

0

High-throughput

0.513

High

1337871

IL27A
Interleukin-27 subunit alpha

1

0

High-throughput

0.513

High

1365200

NDRG1
Protein NDRG1

1

0

High-throughput

0.513

High

1450091

CYRIB
CYFIP-related Rac1 interactor B

1

0

High-throughput

0.513

High

354842

WNT11
Protein Wnt-11

1

4

Small-scale

0.501

High

833487

WNT5A
Protein Wnt-5a

1

4

Small-scale

0.501

High

170453

AURKA
Aurora kinase A

1

2

High-throughput

0.494

High

1116176

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

3

High-throughput

0.494

High

1352024

RBCC1
RB1-inducible coiled-coil protein 1

1

2

High-throughput

0.494

High

126207

AP3B1
AP-3 complex subunit beta-1

1

1

High-throughput

0.489

High

130668

SPT5H
Transcription elongation factor SPT5

1

2

High-throughput

0.489

High

175809

SR140
U2 snRNP-associated SURP motif-containing protein

1

2

High-throughput

0.489

High

191186

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

4

High-throughput

0.489

High

240125

KPRB
Phosphoribosyl pyrophosphate synthase-associated protein 2

1

1

High-throughput

0.489

High

249685

SNX3
Sorting nexin-3

1

2

High-throughput

0.489

High

255897

USO1
General vesicular transport factor p115

1

2

High-throughput

0.489

High

272783

BRE1B
E3 ubiquitin-protein ligase BRE1B

1

4

High-throughput

0.489

High

280882

PR40A
Pre-mRNA-processing factor 40 homolog A

1

5

High-throughput

0.489

High

320807

UBXN7
UBX domain-containing protein 7

1

1

High-throughput

0.489

High

333272

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

2

High-throughput

0.489

High

337848

SGPL1
Sphingosine-1-phosphate lyase 1

1

1

High-throughput

0.489

High

604769

UBF1
Nucleolar transcription factor 1

1

3

High-throughput

0.489

High

611434

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

12

High-throughput

0.489

High

631593

RAB5A
Ras-related protein Rab-5A

1

2

High-throughput

0.489

High

770079

RFC1
Replication factor C subunit 1

1

1

High-throughput

0.489

High

770441

T2FA
General transcription factor IIF subunit 1

1

1

High-throughput

0.489

High

833706

NAA10
N-alpha-acetyltransferase 10

1

3

High-throughput

0.489

High

854973

RECQ1
ATP-dependent DNA helicase Q1

1

1

High-throughput

0.489

High

862591

YAP1
Transcriptional coactivator YAP1

1

15

High-throughput

0.489

High

889223

RBM25
RNA-binding protein 25

1

2

High-throughput

0.489

High

892284

5NTC
Cytosolic purine 5'-nucleotidase

1

2

High-throughput

0.489

High

902240

RAB13
Ras-related protein Rab-13

1

2

High-throughput

0.489

High

941623

CTBP2
C-terminal-binding protein 2

1

1

High-throughput

0.489

High

944433

SYJ2B
Synaptojanin-2-binding protein

1

18

High-throughput

0.489

High

954653

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

1

High-throughput

0.489

High

956035

RAB8A
Ras-related protein Rab-8A

1

2

High-throughput

0.489

High

956628

RAB5B
Ras-related protein Rab-5B

1

3

High-throughput

0.489

High

1058741

CKAP4
Cytoskeleton-associated protein 4

1

3

High-throughput

0.489

High

1081665

HSP7E
Heat shock 70 kDa protein 14

1

1

High-throughput

0.489

High

1091800

PP1R8
Nuclear inhibitor of protein phosphatase 1

1

1

High-throughput

0.489

High

1092367

CSTF3
Cleavage stimulation factor subunit 3

1

2

High-throughput

0.489

High

1095204

RED
Protein Red

1

1

High-throughput

0.489

High

1112003

SNX1
Sorting nexin-1

1

2

High-throughput

0.489

High

1122710

TTL12
Tubulin--tyrosine ligase-like protein 12

1

3

High-throughput

0.489

High

1130897

RRP5
Protein RRP5 homolog

1

2

High-throughput

0.489

High

1138916

SYLM
Leucine--tRNA ligase, mitochondrial

1

1

High-throughput

0.489

High

1149242

SF3A1
Splicing factor 3A subunit 1

1

2

High-throughput

0.489

High

1156632

CCDC6
Coiled-coil domain-containing protein 6

1

2

High-throughput

0.489

High

1177672

PDS5A
Sister chromatid cohesion protein PDS5 homolog A

1

2

High-throughput

0.489

High

1214693

RBM26
RNA-binding protein 26

1

2

High-throughput

0.489

High

1226614

MAP1S
Microtubule-associated protein 1S

1

1

High-throughput

0.489

High

1241533

EDC4
Enhancer of mRNA-decapping protein 4

1

2

High-throughput

0.489

High

1278838

HDGR2
Hepatoma-derived growth factor-related protein 2

1

1

High-throughput

0.489

High

1349238

PI42C
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma

1

1

High-throughput

0.489

High

1349962

PNPT1
Polyribonucleotide nucleotidyltransferase 1, mitochondrial

1

3

High-throughput

0.489

High

1368783

SYMPK
Symplekin

1

1

High-throughput

0.489

High

1381792

FAKD4
FAST kinase domain-containing protein 4

1

1

High-throughput

0.489

High

1395901

TOPK
Lymphokine-activated killer T-cell-originated protein kinase

1

2

High-throughput

0.489

High

1396388

ZFR
Zinc finger RNA-binding protein

1

1

High-throughput

0.489

High

1403307

RBM15
RNA-binding protein 15

1

1

High-throughput

0.489

High

1416890

NAA15
N-alpha-acetyltransferase 15, NatA auxiliary subunit

1

2

High-throughput

0.489

High

1428692

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

1

High-throughput

0.489

High

1429177

NAA50
N-alpha-acetyltransferase 50

1

3

High-throughput

0.489

High

1431451

EHD4
EH domain-containing protein 4

1

2

High-throughput

0.489

High

1434400

EHD1
EH domain-containing protein 1

1

2

High-throughput

0.489

High

1436875

ARMT1
Damage-control phosphatase ARMT1

1

1

High-throughput

0.489

High

1447108

RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B

1

2

High-throughput

0.489

High

1462319

SNX6
Sorting nexin-6

1

2

High-throughput

0.489

High

1491062

SHLB1
Endophilin-B1

1

1

High-throughput

0.489

High

1491228

PTH2
Peptidyl-tRNA hydrolase 2, mitochondrial

1

1

High-throughput

0.489

High

1491253

3BP1
SH3 domain-binding protein 1

1

1

High-throughput

0.489

High

1491447

TBL2
Transducin beta-like protein 2

1

2

High-throughput

0.489

High

1491753

NFS1
Cysteine desulfurase

1

1

High-throughput

0.489

High

1491754

MTCH2
Mitochondrial carrier homolog 2

1

5

High-throughput

0.489

High

411166

WNT1
Proto-oncogene Wnt-1

1

4

Small-scale

0.479

High

950042

KR103
Keratin-associated protein 10-3

1

7

High-throughput

0.439

High

964180

RL37
Large ribosomal subunit protein eL37

1

1

High-throughput

0.439

High

66071

RP1BL
Ras-related protein Rap-1b-like protein

1

10

High-throughput

0.407

High

184658

MK13
Mitogen-activated protein kinase 13

1

2

High-throughput

0.407

High

1008673

CRADD
Death domain-containing protein CRADD

1

0

High-throughput

0.292

High

65838

SMHD1
Structural maintenance of chromosomes flexible hinge domain-containing protein 1

1

0

High-throughput

0.279

Low

135750

DNM1L
Dynamin-1-like protein

1

0

High-throughput

0.279

Low

167034

MGST3
Glutathione S-transferase 3, mitochondrial

1

0

High-throughput

0.279

Low

169024

QCR8
Cytochrome b-c1 complex subunit 8

1

0

High-throughput

0.279

Low

223768

NDUB3
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3

1

0

High-throughput

0.279

Low

295899

FACE1
CAAX prenyl protease 1 homolog

1

0

High-throughput

0.279

Low

302716

SYUG
Gamma-synuclein

1

0

High-throughput

0.279

Low

320192

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.279

Low

329400

LETM1
Mitochondrial proton/calcium exchanger protein

1

0

High-throughput

0.279

Low

354426

TOM40
Mitochondrial import receptor subunit TOM40 homolog

1

0

High-throughput

0.279

Low

357998

CYB5
Cytochrome b5

1

0

High-throughput

0.279

Low

691886

MK03
Mitogen-activated protein kinase 3

1

0

High-throughput

0.279

Low

720080

HMOX2
Heme oxygenase 2

1

0

High-throughput

0.279

Low

720821

PUR8
Adenylosuccinate lyase

1

0

High-throughput

0.279

Low

852092

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.279

Low

873764

GSH0
Glutamate--cysteine ligase regulatory subunit

1

0

High-throughput

0.279

Low

877409

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

0

High-throughput

0.279

Low

922800

CCHL
Holocytochrome c-type synthase

1

0

High-throughput

0.279

Low

937192

ADK
Adenosine kinase

1

0

High-throughput

0.279

Low

1024970

VIGLN
Vigilin

1

0

High-throughput

0.279

Low

1026923

FKBP3
Peptidyl-prolyl cis-trans isomerase FKBP3

1

0

High-throughput

0.279

Low

1085737

TBL3
Transducin beta-like protein 3

1

0

High-throughput

0.279

Low

1086354

TFCP2
Alpha-globin transcription factor CP2

1

0

High-throughput

0.279

Low

1119934

CKAP5
Cytoskeleton-associated protein 5

1

0

High-throughput

0.279

Low

1125969

GAMT
Guanidinoacetate N-methyltransferase

1

0

High-throughput

0.279

Low

1125988

GALE
UDP-glucose 4-epimerase

1

0

High-throughput

0.279

Low

1143706

NOMO1
BOS complex subunit NOMO1

1

0

High-throughput

0.279

Low

1150035

TERF2
Telomeric repeat-binding factor 2

1

0

High-throughput

0.279

Low

1229520

C19L1
CWF19-like protein 1

1

0

High-throughput

0.279

Low

1294439

SPAS2
Spermatogenesis-associated serine-rich protein 2

1

0

High-throughput

0.279

Low

1314819

SUV3
ATP-dependent RNA helicase SUPV3L1, mitochondrial

1

0

High-throughput

0.279

Low

1329148

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

1

0

High-throughput

0.279

Low

1339252

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.279

Low

1349393

RDH11
Retinol dehydrogenase 11

1

0

High-throughput

0.279

Low

1358788

UBCP1
Ubiquitin-like domain-containing CTD phosphatase 1

1

0

High-throughput

0.279

Low

1364332

IP6K1
Inositol hexakisphosphate kinase 1

1

0

High-throughput

0.279

Low

1371124

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

1

0

High-throughput

0.279

Low

1387047

NMD3
60S ribosomal export protein NMD3

1

0

High-throughput

0.279

Low

1387313

RMD1
Regulator of microtubule dynamics protein 1

1

0

High-throughput

0.279

Low

1410899

MGME1
Mitochondrial genome maintenance exonuclease 1

1

0

High-throughput

0.279

Low

1436985

SFXN1
Sideroflexin-1

1

0

High-throughput

0.279

Low

1448012

MBNL1
Muscleblind-like protein 1

1

0

High-throughput

0.279

Low

1449137

TOM22
Mitochondrial import receptor subunit TOM22 homolog

1

0

High-throughput

0.279

Low

1452043

TRM1
tRNA

1

0

High-throughput

0.279

Low

1460162

NDUAC
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12

1

0

High-throughput

0.279

Low

1490813

RRP44
Exosome complex exonuclease RRP44

1

0

High-throughput

0.279

Low

1490860

GSTK1
Glutathione S-transferase kappa 1

1

0

High-throughput

0.279

Low

1490879

DDX52
Probable ATP-dependent RNA helicase DDX52

1

0

High-throughput

0.279

Low

1491493

PPME1
Protein phosphatase methylesterase 1

1

0

High-throughput

0.279

Low

124858

AIP
AH receptor-interacting protein

1

0

High-throughput

0.232

Low

1439348

GPN1
GPN-loop GTPase 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025