Protein: DJC21
DnaJ homolog subfamily C member 21 (DnaJ homolog subfamily A member 5) (Protein GS3)

Gene: DJC21, DNAJC21
Organism: Homo sapiens
Interactions: 78
UniProt ID: Q5F1R6

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005730 - nucleolus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005840 - ribosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

930717

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

1

3

High-throughput

0.691

High

396261

ESR1
Estrogen receptor

3

20

High-throughput

0.633

High

274609

DNJB6
DnaJ homolog subfamily B member 6

1

15

High-throughput

0.618

High

986465

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

5

High-throughput

0.618

High

1204283

DNJC5
DnaJ homolog subfamily C member 5

1

16

High-throughput

0.618

High

1204296

RT18B
Small ribosomal subunit protein mS40

2

1

High-throughput

0.558

High

415619

HSPB1
Heat shock protein beta-1

1

1

High-throughput

0.541

High

1204279

MTEF1
Transcription termination factor 1, mitochondrial

1

0

High-throughput

0.537

High

542542

TOP2A
DNA topoisomerase 2-alpha

1

1

High-throughput

0.536

High

616332

RCC1
Regulator of chromosome condensation

1

4

High-throughput

0.536

High

655223

SFPQ
Splicing factor, proline- and glutamine-rich

1

3

High-throughput

0.536

High

693778

RL10
Large ribosomal subunit protein uL16

1

3

High-throughput

0.536

High

788676

SRP14
Signal recognition particle 14 kDa protein

1

5

High-throughput

0.536

High

969900

RS16
Small ribosomal subunit protein uS9

1

1

High-throughput

0.536

High

992784

RACK1
Small ribosomal subunit protein RACK1

1

8

High-throughput

0.536

High

1016041

RL19
Large ribosomal subunit protein eL19

1

2

High-throughput

0.536

High

1039514

TOP2B
DNA topoisomerase 2-beta

1

1

High-throughput

0.536

High

1057169

PRDX1
Peroxiredoxin-1

1

1

High-throughput

0.536

High

1155438

EZH2
Histone-lysine N-methyltransferase EZH2

1

1

High-throughput

0.536

High

1162957

H2B2E
Histone H2B type 2-E

1

6

High-throughput

0.536

High

1204269

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

4

High-throughput

0.536

High

298725

ATP5H
ATP synthase peripheral stalk subunit d, mitochondrial

2

7

High-throughput

0.533

High

886507

CTCF
Transcriptional repressor CTCF

1

6

High-throughput

0.515

High

1204275

H2B1H
Histone H2B type 1-H

1

6

High-throughput

0.515

High

913657

VAV2
Guanine nucleotide exchange factor VAV2

1

5

High-throughput

0.508

High

1204280

H2A1J
Histone H2A type 1-J

1

6

High-throughput

0.489

High

132087

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

5

High-throughput

0.479

High

241891

PRKN
E3 ubiquitin-protein ligase parkin

1

11

High-throughput

0.479

High

345910

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

6

High-throughput

0.479

High

406254

MYCN
N-myc proto-oncogene protein

1

7

High-throughput

0.479

High

428800

RLA0
Large ribosomal subunit protein uL10

1

7

High-throughput

0.479

High

567420

TCTP
Translationally-controlled tumor protein

1

3

High-throughput

0.479

High

680381

ATPA
ATP synthase F(1) complex subunit alpha, mitochondrial

1

4

High-throughput

0.479

High

785213

RL4
Large ribosomal subunit protein uL4

1

10

High-throughput

0.479

High

867186

CAPZB
F-actin-capping protein subunit beta

1

3

High-throughput

0.479

High

902488

RT29
Small ribosomal subunit protein mS29

1

1

High-throughput

0.479

High

941177

IF6
Eukaryotic translation initiation factor 6

1

2

High-throughput

0.479

High

975730

RL7A
Large ribosomal subunit protein eL8

1

7

High-throughput

0.479

High

1039244

RL6
Large ribosomal subunit protein eL6

1

6

High-throughput

0.479

High

1045365

TF65
Transcription factor p65

1

5

High-throughput

0.479

High

1057768

RL18
Large ribosomal subunit protein eL18

1

5

High-throughput

0.479

High

1105953

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

20

High-throughput

0.479

High

1123658

DCTN1
Dynactin subunit 1

1

1

High-throughput

0.479

High

1137752

TNIP1
TNFAIP3-interacting protein 1

1

7

High-throughput

0.479

High

1204268

RNF43
E3 ubiquitin-protein ligase RNF43

1

11

High-throughput

0.479

High

1204270

NUDC3
NudC domain-containing protein 3

1

3

High-throughput

0.479

High

1204272

RT27
Small ribosomal subunit protein mS27

1

2

High-throughput

0.479

High

1204273

RT31
Small ribosomal subunit protein mS31

1

1

High-throughput

0.479

High

1204274

HDAC2
Histone deacetylase 2

1

5

High-throughput

0.479

High

1204276

ZN622
Cytoplasmic 60S subunit biogenesis factor ZNF622

1

3

High-throughput

0.479

High

1204277

PTCD3
Small ribosomal subunit protein mS39

1

1

High-throughput

0.479

High

1204278

RING2
E3 ubiquitin-protein ligase RING2

1

8

High-throughput

0.479

High

1204284

PKHA4
Pleckstrin homology domain-containing family A member 4

1

15

High-throughput

0.479

High

1204285

CYBP
Calcyclin-binding protein

1

2

High-throughput

0.479

High

1204286

ANLN
Anillin

1

5

High-throughput

0.479

High

1204289

ZRAN1
Ubiquitin thioesterase ZRANB1

1

9

High-throughput

0.479

High

1204291

FZR1
Fizzy-related protein homolog

1

11

High-throughput

0.479

High

1204294

RT07
Small ribosomal subunit protein uS7m

1

3

High-throughput

0.479

High

1204295

RT23
Small ribosomal subunit protein mS23

1

1

High-throughput

0.479

High

482495

F16P1
Fructose-1,6-bisphosphatase 1

1

0

High-throughput

0.458

High

957752

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

0

High-throughput

0.458

High

1204271

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

1204288

F120A
Constitutive coactivator of PPAR-gamma-like protein 1

1

0

High-throughput

0.458

High

1204292

DIM1
Dimethyladenosine transferase

1

0

High-throughput

0.458

High

843634

HD
Huntingtin

1

5

High-throughput

0.457

High

391623

FRIH
Ferritin heavy chain

1

1

High-throughput

0.445

High

106059

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

136908

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

4

High-throughput

0.437

High

522435

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

3

High-throughput

0.437

High

1195646

Q4LE69
Phosphatidylinositol 4-kinase alpha

1

3

High-throughput

0.437

High

1204287

MIC19
MICOS complex subunit MIC19

1

3

High-throughput

0.437

High

1204290

HECD1
E3 ubiquitin-protein ligase HECTD1

1

4

High-throughput

0.437

High

1012702

RT06
Small ribosomal subunit protein bS6m

1

0

High-throughput

0.279

Low

1204281

NIPS1
Protein NipSnap homolog 1

1

0

High-throughput

0.279

Low

1204282

BPIA3
BPI fold-containing family A member 3

1

0

High-throughput

0.279

Low

1204293

RT17
Small ribosomal subunit protein uS17m

1

0

High-throughput

0.279

Low

1093466

COASY
Bifunctional coenzyme A synthase

1

0

High-throughput

0.249

Low

1037186

H11
Histone H1.1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025