Protein: COASY
Bifunctional coenzyme A synthase (CoA synthase) (NBP) (POV-2) [Includes: Phosphopantetheine adenylyltransferase (EC 2.7.7.3) (Dephospho-CoA pyrophosphorylase) (Pantetheine-phosphate adenylyltransferase) (PPAT); Dephospho-CoA kinase (DPCK) (EC 2.7.1.24) (Dephosphocoenzyme A kinase) (DPCOAK)]

Gene: COASY
Organism: Homo sapiens
Interactions: 85
UniProt ID: Q13057

Gene Ontology (top 5):
GO:0004140 - dephospho-CoA kinase activity
GO:0004595 - pantetheine-phosphate adenylyltransferase activity
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1093490

DNAI2
Dynein axonemal intermediate chain 2

1

1

High-throughput

0.618

High

658599

KS6B1
Ribosomal protein S6 kinase beta-1

1

2

Small-scale

0.589

High

502338

H2A1
Histone H2A type 1

2

0

High-throughput

0.585

High

609668

LEG3
Galectin-3

2

0

High-throughput

0.585

High

692689

CALL3
Calmodulin-like protein 3

2

0

High-throughput

0.585

High

1093483

LRC15
Leucine-rich repeat-containing protein 15

2

0

High-throughput

0.585

High

241549

PRKN
E3 ubiquitin-protein ligase parkin

2

1

High-throughput

0.584

High

1093467

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

1

High-throughput

0.571

High

326699

DUS14
Dual specificity protein phosphatase 14

2

1

High-throughput

0.558

High

1053654

PTN11
Tyrosine-protein phosphatase non-receptor type 11

1

0

Small-scale

0.537

High

1093486

TCPQM
T-complex protein 1 subunit theta-like 2

1

2

High-throughput

0.536

High

563705

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.518

High

859808

RL28
Large ribosomal subunit protein eL28

1

0

High-throughput

0.513

High

996445

ACTS
Actin, alpha skeletal muscle

1

0

High-throughput

0.513

High

1093459

G3BP1
Ras GTPase-activating protein-binding protein 1

1

0

High-throughput

0.513

High

1093471

FAHD1
Oxaloacetate tautomerase FAHD1, mitochondrial

1

0

High-throughput

0.513

High

1093489

UBXN6
UBX domain-containing protein 6

1

0

High-throughput

0.513

High

1093499

AMACR
Alpha-methylacyl-CoA racemase

1

0

High-throughput

0.513

High

463492

LYN
Tyrosine-protein kinase Lyn

1

2

Small-scale

0.501

High

557267

SRC
Proto-oncogene tyrosine-protein kinase Src

1

2

Small-scale

0.501

High

849154

KSYK
Tyrosine-protein kinase SYK

1

1

Small-scale

0.501

High

1054102

BTK
Tyrosine-protein kinase BTK

1

2

Small-scale

0.501

High

302052

SEGN
Secretagogin

1

1

High-throughput

0.489

High

1093485

EFMT3
EEF1A lysine methyltransferase 3

1

1

High-throughput

0.489

High

1093488

KCD14
BTB/POZ domain-containing protein KCTD14

1

1

High-throughput

0.489

High

422022

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

1093496

KS6B2
Ribosomal protein S6 kinase beta-2

1

2

Small-scale

0.479

High

105847

APRIO
Alternative prion protein

1

0

High-throughput

0.458

High

347669

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

505431

CISD3
CDGSH iron-sulfur domain-containing protein 3, mitochondrial

1

0

High-throughput

0.458

High

875642

PRC2A
Protein PRRC2A

1

0

High-throughput

0.458

High

977973

RHOB
Rho-related GTP-binding protein RhoB

1

0

High-throughput

0.458

High

986385

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

0

High-throughput

0.458

High

1035582

KIF23
Kinesin-like protein KIF23

1

0

High-throughput

0.458

High

1093465

FSCN1
Fascin

1

0

High-throughput

0.458

High

1093472

MIC27
MICOS complex subunit MIC27

1

0

High-throughput

0.458

High

588581

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

695337

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

768074

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

1093473

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

1093500

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

1

Small-scale

0.437

High

231565

PRKY
Putative serine/threonine-protein kinase PRKY

1

0

High-throughput

0.426

High

619768

VCAM1
Vascular cell adhesion protein 1

1

0

High-throughput

0.426

High

1093476

CNTRB
Centrobin

2

0

High-throughput

0.335

High

754566

S10A3
Protein S100-A3

2

0

High-throughput

0.318

High

1093468

HPHL1
Ferroxidase HEPHL1

2

0

High-throughput

0.318

High

1093474

DSG4
Desmoglein-4

2

0

High-throughput

0.318

High

1093475

MIB1
E3 ubiquitin-protein ligase MIB1

2

0

High-throughput

0.313

High

1093480

K1958
Uncharacterized protein KIAA1958

1

0

High-throughput

0.299

High

777390

K1C20
Keratin, type I cytoskeletal 20

1

0

High-throughput

0.282

High

74477

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

0

High-throughput

0.279

Low

134709

SAP18
Histone deacetylase complex subunit SAP18

1

0

High-throughput

0.279

Low

158435

RFXK
DNA-binding protein RFXANK

1

0

High-throughput

0.279

Low

216174

MTG8R
Protein CBFA2T2

1

0

High-throughput

0.279

Low

295578

CIB2
Calcium and integrin-binding family member 2

1

0

High-throughput

0.279

Low

298163

DCTN3
Dynactin subunit 3

1

0

High-throughput

0.279

Low

351775

LGI1
Leucine-rich glioma-inactivated protein 1

1

0

High-throughput

0.279

Low

959464

YPEL3
Protein yippee-like 3

1

0

High-throughput

0.279

Low

1093463

TRADD
Tumor necrosis factor receptor type 1-associated DEATH domain protein

1

0

High-throughput

0.279

Low

1093464

SSX2
Protein SSX2

1

0

High-throughput

0.279

Low

1093470

PLBL1
Phospholipase B-like 1

1

0

High-throughput

0.279

Low

1093477

CLASR
CLK4-associating serine/arginine rich protein

1

0

High-throughput

0.279

Low

1093481

UBP32
Ubiquitin carboxyl-terminal hydrolase 32

1

0

High-throughput

0.279

Low

1093487

NPAS1
Neuronal PAS domain-containing protein 1

1

0

High-throughput

0.279

Low

1093493

GALT9
Polypeptide N-acetylgalactosaminyltransferase 9

1

0

High-throughput

0.279

Low

1093494

CENPM
Centromere protein M

1

0

High-throughput

0.279

Low

1093501

PSG11
Pregnancy-specific beta-1-glycoprotein 11

1

0

High-throughput

0.279

Low

1093482

PJA1
E3 ubiquitin-protein ligase Praja-1

1

0

Small-scale

0.261

Low

830654

CCNF
Cyclin-F

1

0

High-throughput

0.249

Low

964904

WDR5
WD repeat-containing protein 5

1

0

High-throughput

0.249

Low

1093460

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.249

Low

1093461

PKP1
Plakophilin-1

1

0

High-throughput

0.249

Low

1093462

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.249

Low

1093466

DJC21
DnaJ homolog subfamily C member 21

1

0

High-throughput

0.249

Low

1093469

EDC4
Enhancer of mRNA-decapping protein 4

1

0

Small-scale

0.249

Low

1093478

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.249

Low

1093479

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.249

Low

1093484

HDAC2
Histone deacetylase 2

1

0

High-throughput

0.249

Low

1093491

ATG5
Autophagy protein 5

1

0

High-throughput

0.249

Low

1093492

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1093495

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.249

Low

1093497

DJB11
DnaJ homolog subfamily B member 11

1

0

High-throughput

0.249

Low

1093498

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.249

Low

1093502

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low

516661

VSIG8
V-set and immunoglobulin domain-containing protein 8

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025