Protein: SACA1
Sperm acrosome membrane-associated protein 1 (Sperm acrosomal membrane-associated protein 32)

Gene: SACA1, SPACA1
Organism: Homo sapiens
Interactions: 114
UniProt ID: Q9HBV2

Gene Ontology (top 5):
GO:0001675 - acrosome assembly
GO:0002079 - inner acrosomal membrane
GO:0002080 - acrosomal membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1281233

VP13B
Intermembrane lipid transfer protein VPS13B

3

0

High-throughput

0.638

High

333521

MPZL1
Myelin protein zero-like protein 1

3

1

High-throughput

0.609

High

1258285

SAMC
Mitochondrial S-adenosylmethionine carrier protein

3

2

High-throughput

0.609

High

1363858

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

3

1

High-throughput

0.609

High

1435236

ANTR1
Anthrax toxin receptor 1

3

1

High-throughput

0.609

High

688418

PPLA
Phospholamban

2

0

High-throughput

0.580

High

324367

SLIK5
SLIT and NTRK-like protein 5

2

1

High-throughput

0.574

High

692268

VATL
V-type proton ATPase 16 kDa proteolipid subunit c

2

1

High-throughput

0.553

High

932710

EMP1
Epithelial membrane protein 1

2

2

High-throughput

0.553

High

932765

EMP3
Epithelial membrane protein 3

2

2

High-throughput

0.553

High

986916

CCG7
Voltage-dependent calcium channel gamma-7 subunit

2

1

High-throughput

0.553

High

1030386

PMP22
Peripheral myelin protein 22

2

2

High-throughput

0.553

High

1404142

VATO
V-type proton ATPase 21 kDa proteolipid subunit c''

2

1

High-throughput

0.553

High

1417684

TX101
Testis-expressed protein 101

1

0

High-throughput

0.513

High

249384

MPZL2
Myelin protein zero-like protein 2

1

1

High-throughput

0.489

High

332249

UCP5
Brain mitochondrial carrier protein 1

1

1

High-throughput

0.489

High

552400

ADT3
ADP/ATP translocase 3

1

1

High-throughput

0.489

High

1438439

TPC
Mitochondrial thiamine pyrophosphate carrier

1

2

High-throughput

0.489

High

1438455

AP1M2
AP-1 complex subunit mu-2

1

1

High-throughput

0.489

High

1216530

BIG3
Brefeldin A-inhibited guanine nucleotide-exchange protein 3

1

2

High-throughput

0.437

High

1417309

AP1M1
AP-1 complex subunit mu-1

1

1

High-throughput

0.437

High

1438454

BIG2
Brefeldin A-inhibited guanine nucleotide-exchange protein 2

1

2

High-throughput

0.437

High

136552

GOLI4
Golgi integral membrane protein 4

3

0

High-throughput

0.347

High

162043

MP2K7
Dual specificity mitogen-activated protein kinase kinase 7

3

0

High-throughput

0.347

High

219096

RA51C
DNA repair protein RAD51 homolog 3

3

0

High-throughput

0.347

High

909188

NEK4
Serine/threonine-protein kinase Nek4

3

0

High-throughput

0.347

High

1032661

AT2B2
Plasma membrane calcium-transporting ATPase 2

3

0

High-throughput

0.347

High

1086559

TROP
Trophinin

3

0

High-throughput

0.347

High

1103798

PLD1
Phospholipase D1

3

0

High-throughput

0.347

High

1108718

TBB3
Tubulin beta-3 chain

3

0

High-throughput

0.347

High

1129984

MELK
Maternal embryonic leucine zipper kinase

3

0

High-throughput

0.347

High

1133232

STAR3
StAR-related lipid transfer protein 3

3

0

High-throughput

0.347

High

1135936

FAKD3
FAST kinase domain-containing protein 3, mitochondrial

3

0

High-throughput

0.347

High

1219347

ECM29
Proteasome adapter and scaffold protein ECM29

3

0

High-throughput

0.347

High

1228856

LMBD2
G-protein coupled receptor-associated protein LMBRD2

3

0

High-throughput

0.347

High

1238331

TYW1B
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1B

3

0

High-throughput

0.347

High

1278519

TT21B
Tetratricopeptide repeat protein 21B

3

0

High-throughput

0.347

High

1306923

DCP2
m7GpppN-mRNA hydrolase

3

0

High-throughput

0.347

High

1310058

DEN6A
Protein DENND6A

3

0

High-throughput

0.347

High

1315604

MICU2
Calcium uptake protein 2, mitochondrial

3

0

High-throughput

0.347

High

1335572

DGLB
Diacylglycerol lipase-beta

3

0

High-throughput

0.347

High

1372228

TATD2
3'-5' RNA nuclease TATDN2

3

0

High-throughput

0.347

High

1387231

TIM14
Mitochondrial import inner membrane translocase subunit TIM14

3

0

High-throughput

0.347

High

1394682

KIRR1
Kin of IRRE-like protein 1

3

0

High-throughput

0.347

High

1412593

CQ080
Mitochondrial nucleoid-associated protein 1

3

0

High-throughput

0.347

High

1420846

SEM4C
Semaphorin-4C

3

0

High-throughput

0.347

High

1438440

K1586
E3 SUMO-protein ligase KIAA1586

3

0

High-throughput

0.347

High

1438445

INT7
Integrator complex subunit 7

3

0

High-throughput

0.347

High

1438447

LRFN1
Leucine-rich repeat and fibronectin type III domain-containing protein 1

3

0

High-throughput

0.347

High

1438448

COMD3
COMM domain-containing protein 3

3

0

High-throughput

0.347

High

1438449

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

3

0

High-throughput

0.347

High

161891

IMPA2
Inositol monophosphatase 2

2

0

High-throughput

0.318

High

318163

IPO13
Importin-13

2

0

High-throughput

0.318

High

1036388

BDH
D-beta-hydroxybutyrate dehydrogenase, mitochondrial

2

0

High-throughput

0.318

High

1230763

HEAT6
HEAT repeat-containing protein 6

2

0

High-throughput

0.318

High

1287608

ADCK1
AarF domain-containing protein kinase 1

2

0

High-throughput

0.318

High

1293506

COMD2
COMM domain-containing protein 2

2

0

High-throughput

0.318

High

1327540

DTWD1
tRNA-uridine aminocarboxypropyltransferase 1

2

0

High-throughput

0.318

High

1350249

DC2L1
Cytoplasmic dynein 2 light intermediate chain 1

2

0

High-throughput

0.318

High

1411480

TM2D3
TM2 domain-containing protein 3

2

0

High-throughput

0.318

High

58654

SRTM1
Serine-rich and transmembrane domain-containing protein 1

2

0

High-throughput

0.316

High

1315995

NRSN1
Neurensin-1

2

0

High-throughput

0.316

High

641477

CD72
B-cell differentiation antigen CD72

2

0

High-throughput

0.316

High

843351

NSG1
Neuronal vesicle trafficking-associated protein 1

2

0

High-throughput

0.316

High

1081332

SMAGP
Small cell adhesion glycoprotein

2

0

High-throughput

0.316

High

1092095

BNIP3
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3

2

0

High-throughput

0.316

High

1102521

SGCG
Gamma-sarcoglycan

2

0

High-throughput

0.316

High

1195552

CTXN3
Cortexin-3

2

0

High-throughput

0.316

High

1322570

LSME2
Leucine-rich single-pass membrane protein 2

2

0

High-throughput

0.316

High

1329249

CLD19
Claudin-19

2

0

High-throughput

0.316

High

1329668

SERP2
Stress-associated endoplasmic reticulum protein 2

2

0

High-throughput

0.316

High

1390247

GIMA5
GTPase IMAP family member 5

2

0

High-throughput

0.316

High

1410843

TMM47
Transmembrane protein 47

2

0

High-throughput

0.316

High

1420032

SMIM3
Small integral membrane protein 3

2

0

High-throughput

0.316

High

1438441

PLCD
1-acyl-sn-glycerol-3-phosphate acyltransferase delta

2

0

High-throughput

0.316

High

1438442

RPRM
Protein reprimo

2

0

High-throughput

0.316

High

1438443

TM140
Transmembrane protein 140

2

0

High-throughput

0.316

High

48802

ESYT2
Extended synaptotagmin-2

1

0

High-throughput

0.279

Low

349577

TSN15
Tetraspanin-15

1

0

High-throughput

0.279

Low

582198

INGR1
Interferon gamma receptor 1

1

0

High-throughput

0.279

Low

655011

ITA6
Integrin alpha-6

1

0

High-throughput

0.279

Low

787344

ACV1B
Activin receptor type-1B

1

0

High-throughput

0.279

Low

834695

TNFL9
Tumor necrosis factor ligand superfamily member 9

1

0

High-throughput

0.279

Low

1062190

PCDH1
Protocadherin-1

1

0

High-throughput

0.279

Low

1063017

DDR1
Epithelial discoidin domain-containing receptor 1

1

0

High-throughput

0.279

Low

1217201

RIF1
Telomere-associated protein RIF1

1

0

High-throughput

0.279

Low

1323352

VPS52
Vacuolar protein sorting-associated protein 52 homolog

1

0

High-throughput

0.279

Low

1350145

SPP
Signal peptide peptidase

1

0

High-throughput

0.279

Low

1356110

SCRB1
Scavenger receptor class B member 1

1

0

High-throughput

0.279

Low

1357042

S20A1
Sodium-dependent phosphate transporter 1

1

0

High-throughput

0.279

Low

1384630

S67A1
Solute carrier family 67 member A1

1

0

High-throughput

0.279

Low

1428793

SRR
Serine racemase

1

0

High-throughput

0.279

Low

1430690

F234A
Protein FAM234A

1

0

High-throughput

0.279

Low

1438444

CC50A
Cell cycle control protein 50A

1

0

High-throughput

0.279

Low

1438452

ITM2B
Integral membrane protein 2B

1

0

High-throughput

0.279

Low

1421301

THS7B
Thrombospondin type-1 domain-containing protein 7B

1

0

High-throughput

0.268

Low

71362

F1712
Protein FAM171A2

1

0

High-throughput

0.249

Low

72678

UPK3L
Uroplakin-3b-like protein 1

1

0

High-throughput

0.249

Low

317927

LTN1
E3 ubiquitin-protein ligase listerin

1

0

High-throughput

0.249

Low

732850

GLPK
Glycerol kinase

1

0

High-throughput

0.249

Low

838182

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

0

High-throughput

0.249

Low

940591

ATP68
ATP synthase F(0) complex subunit j, mitochondrial

1

0

High-throughput

0.249

Low

1005775

RPP38
Ribonuclease P protein subunit p38

1

0

High-throughput

0.249

Low

1308036

T126B
Complex I assembly factor TMEM126B, mitochondrial

1

0

High-throughput

0.249

Low

1336133

GLT11
Polypeptide N-acetylgalactosaminyltransferase 11

1

0

High-throughput

0.249

Low

1336977

SIMC1
SUMO-interacting motif-containing protein 1

1

0

High-throughput

0.249

Low

1429660

COMD4
COMM domain-containing protein 4

1

0

High-throughput

0.249

Low

1438446

PAPD1
Poly(A) RNA polymerase, mitochondrial

1

0

High-throughput

0.249

Low

1438451

DYN3
Dynamin-3

1

0

High-throughput

0.249

Low

1438453

TIM16
Mitochondrial import inner membrane translocase subunit TIM16

1

0

High-throughput

0.249

Low

154576

PLPP3
Phospholipid phosphatase 3

1

0

High-throughput

0.232

Low

568177

PLSL
Plastin-2

1

0

High-throughput

0.232

Low

877386

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

0

High-throughput

0.232

Low

1438450

NAGPA
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025