Protein: PSD3
PH and SEC7 domain-containing protein 3 (Epididymis tissue protein Li 20mP) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 D) (Exchange factor for ARF6 D) (Hepatocellular carcinoma-associated antigen 67) (Pleckstrin homology and SEC7 domain-containing protein 3)

Gene: PSD3
Organism: Homo sapiens
Interactions: 140
UniProt ID: Q9NYI0

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0014069 - postsynaptic density
GO:0032012 - regulation of ARF protein signal transduction
GO:0032587 - ruffle membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

982552

1433F
14-3-3 protein eta

3

20

High-throughput

0.609

High

927589

1433Z
14-3-3 protein zeta/delta

2

20

High-throughput

0.580

High

1299066

ARAP1
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1

1

7

Small-scale

0.555

High

913147

ARF6
ADP-ribosylation factor 6

1

14

High-throughput

0.553

High

950731

ARF5
ADP-ribosylation factor 5

1

13

High-throughput

0.514

High

905184

1433G
14-3-3 protein gamma

1

20

High-throughput

0.506

High

647326

1433T
14-3-3 protein theta

1

20

High-throughput

0.489

High

683761

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.489

High

725586

COPB2
Coatomer subunit beta'

1

3

High-throughput

0.489

High

863582

COPA
Coatomer subunit alpha

1

3

High-throughput

0.489

High

910092

1433E
14-3-3 protein epsilon

1

4

High-throughput

0.489

High

1284828

EFMT3
EEF1A lysine methyltransferase 3

1

3

High-throughput

0.489

High

1306166

NPAS1
Neuronal PAS domain-containing protein 1

1

2

High-throughput

0.489

High

925672

RAC1
Ras-related C3 botulinum toxin substrate 1

1

10

High-throughput

0.479

High

1152144

LTOR1
Ragulator complex protein LAMTOR1

1

2

High-throughput

0.479

High

1335347

RHOF
Rho-related GTP-binding protein RhoF

1

14

High-throughput

0.479

High

476476

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

8

High-throughput

0.457

High

307135

RTN3
Reticulon-3

1

2

High-throughput

0.445

High

945899

NUCB2
Nucleobindin-2

1

1

High-throughput

0.445

High

1343297

RTN4
Reticulon-4

1

2

High-throughput

0.445

High

594269

MX1
Interferon-induced GTP-binding protein Mx1

1

1

Small-scale

0.439

High

171248

CTDSL
CTD small phosphatase-like protein

1

3

High-throughput

0.437

High

305658

ZFPL1
Zinc finger protein-like 1

1

2

High-throughput

0.437

High

318236

DIRA3
GTP-binding protein Di-Ras3

1

6

High-throughput

0.437

High

348966

RASN
GTPase NRas

1

17

High-throughput

0.437

High

350612

RASK
GTPase KRas

1

16

High-throughput

0.437

High

411875

LCK
Tyrosine-protein kinase Lck

1

1

High-throughput

0.437

High

434040

LYN
Tyrosine-protein kinase Lyn

1

1

High-throughput

0.437

High

507273

LAMP1
Lysosome-associated membrane glycoprotein 1

1

5

High-throughput

0.437

High

545659

RAC2
Ras-related C3 botulinum toxin substrate 2

1

8

High-throughput

0.437

High

564710

RHOQ
Rho-related GTP-binding protein RhoQ

1

13

High-throughput

0.437

High

567298

CXA1
Gap junction alpha-1 protein

1

4

High-throughput

0.437

High

575604

EGR1
Early growth response protein 1

1

1

High-throughput

0.437

High

577070

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

1

2

High-throughput

0.437

High

608157

FGFR4
Fibroblast growth factor receptor 4

1

3

High-throughput

0.437

High

617146

PTPRG
Receptor-type tyrosine-protein phosphatase gamma

1

2

High-throughput

0.437

High

776410

MLH1
DNA mismatch repair protein Mlh1

1

3

High-throughput

0.437

High

793497

MUC18
Cell surface glycoprotein MUC18

1

1

High-throughput

0.437

High

869895

PMS2
Mismatch repair endonuclease PMS2

1

3

High-throughput

0.437

High

892630

RAC3
Ras-related C3 botulinum toxin substrate 3

1

10

High-throughput

0.437

High

894511

CDC42
Cell division control protein 42 homolog

1

10

High-throughput

0.437

High

895298

RAB2A
Ras-related protein Rab-2A

1

9

High-throughput

0.437

High

914406

RB11A
Ras-related protein Rab-11A

1

6

High-throughput

0.437

High

916024

RHOB
Rho-related GTP-binding protein RhoB

1

11

High-throughput

0.437

High

951401

RHOG
Rho-related GTP-binding protein RhoG

1

8

High-throughput

0.437

High

975070

CAV1
Caveolin-1

1

1

High-throughput

0.437

High

1057410

SMC1A
Structural maintenance of chromosomes protein 1A

1

2

High-throughput

0.437

High

1070421

RAB35
Ras-related protein Rab-35

1

8

High-throughput

0.437

High

1080801

ZYX
Zyxin

1

2

High-throughput

0.437

High

1172010

TRI67
Tripartite motif-containing protein 67

1

5

High-throughput

0.437

High

1330422

DNJC5
DnaJ homolog subfamily C member 5

1

2

High-throughput

0.437

High

1330954

RHOJ
Rho-related GTP-binding protein RhoJ

1

13

High-throughput

0.437

High

1336470

E41LA
Band 4.1-like protein 4A

1

7

High-throughput

0.437

High

1348511

SMC3
Structural maintenance of chromosomes protein 3

1

1

High-throughput

0.437

High

1348512

LAMP3
Lysosome-associated membrane glycoprotein 3

1

5

High-throughput

0.437

High

1065443

RB3GP
Rab3 GTPase-activating protein catalytic subunit

1

0

High-throughput

0.426

High

48537

ESYT2
Extended synaptotagmin-2

1

3

High-throughput

0.407

High

99827

F5H6I7
Atlastin GTPase 3

1

2

High-throughput

0.407

High

201069

VIP2
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2

1

1

High-throughput

0.407

High

258981

RTN2
Reticulon-2

1

2

High-throughput

0.407

High

277145

STAM2
Signal transducing adapter molecule 2

1

4

High-throughput

0.407

High

297795

MICA2
[F-actin]-monooxygenase MICAL2

1

2

High-throughput

0.407

High

310844

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

2

High-throughput

0.407

High

432967

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

1

High-throughput

0.407

High

502613

BIP
Endoplasmic reticulum chaperone BiP

1

1

High-throughput

0.407

High

532238

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

1

High-throughput

0.407

High

653752

CALR
Calreticulin

1

1

High-throughput

0.407

High

654846

CALX
Calnexin

1

1

High-throughput

0.407

High

833357

TMEDA
Transmembrane emp24 domain-containing protein 10

1

2

High-throughput

0.407

High

847693

BAP31
B-cell receptor-associated protein 31

1

1

High-throughput

0.407

High

863351

COPB
Coatomer subunit beta

1

2

High-throughput

0.407

High

924193

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

6

High-throughput

0.407

High

1044202

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

3

High-throughput

0.407

High

1062692

EMC2
ER membrane protein complex subunit 2

1

1

High-throughput

0.407

High

1070940

RCN1
Reticulocalbin-1

1

1

High-throughput

0.407

High

1071852

TMED2
Transmembrane emp24 domain-containing protein 2

1

2

High-throughput

0.407

High

1072973

DHC24
Delta(24)-sterol reductase

1

1

High-throughput

0.407

High

1077730

NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

1

1

High-throughput

0.407

High

1121024

DHB12
Very-long-chain 3-oxoacyl-CoA reductase

1

3

High-throughput

0.407

High

1165436

LCLT1
Lysocardiolipin acyltransferase 1

1

1

High-throughput

0.407

High

1174546

UB2R2
Ubiquitin-conjugating enzyme E2 R2

1

1

High-throughput

0.407

High

1224296

PACE1
Protein-associating with the carboxyl-terminal domain of ezrin

1

2

High-throughput

0.407

High

1240336

DHB11
Estradiol 17-beta-dehydrogenase 11

1

2

High-throughput

0.407

High

1245554

ATLA2
Atlastin-2

1

2

High-throughput

0.407

High

1261651

SCFD1
Sec1 family domain-containing protein 1

1

3

High-throughput

0.407

High

1263635

ATLA1
Atlastin-1

1

2

High-throughput

0.407

High

1282664

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

1

High-throughput

0.407

High

1296182

SCYL1
N-terminal kinase-like protein

1

5

High-throughput

0.407

High

1311427

ESYT1
Extended synaptotagmin-1

1

1

High-throughput

0.407

High

1318108

WDR11
WD repeat-containing protein 11

1

1

High-throughput

0.407

High

1327788

RGAP1
Rac GTPase-activating protein 1

1

3

High-throughput

0.407

High

1330226

TMX1
Thioredoxin-related transmembrane protein 1

1

1

High-throughput

0.407

High

1345741

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

1

High-throughput

0.407

High

1348509

VAPA
Vesicle-associated membrane protein-associated protein A

1

2

High-throughput

0.407

High

1348510

COPG2
Coatomer subunit gamma-2

1

4

High-throughput

0.407

High

1348513

DHRS7
Dehydrogenase/reductase SDR family member 7

1

1

High-throughput

0.407

High

1348514

TMED5
Transmembrane emp24 domain-containing protein 5

1

2

High-throughput

0.407

High

1348516

COPG1
Coatomer subunit gamma-1

1

4

High-throughput

0.407

High

279734

FLOT1
Flotillin-1

1

0

High-throughput

0.249

Low

670250

MARCS
Myristoylated alanine-rich C-kinase substrate

1

0

High-throughput

0.249

Low

940581

CXAR
Coxsackievirus and adenovirus receptor

1

0

High-throughput

0.249

Low

1084208

OCLN
Occludin

1

0

High-throughput

0.249

Low

1191086

WAPL
Wings apart-like protein homolog

1

0

High-throughput

0.249

Low

1232583

STAG2
Cohesin subunit SA-2

1

0

High-throughput

0.249

Low

1267886

CNOT9
CCR4-NOT transcription complex subunit 9

1

0

High-throughput

0.249

Low

1283076

CK052
Uncharacterized protein C11orf52

1

0

High-throughput

0.249

Low

1342879

DCP1A
mRNA-decapping enzyme 1A

1

0

High-throughput

0.249

Low

50260

HACL2
2-hydroxyacyl-CoA lyase 2

1

0

High-throughput

0.232

Low

58160

NBAS
NBAS subunit of NRZ tethering complex

1

0

High-throughput

0.232

Low

149758

COPE
Coatomer subunit epsilon

1

0

High-throughput

0.232

Low

199406

ZW10
Centromere/kinetochore protein zw10 homolog

1

0

High-throughput

0.232

Low

202988

EMC8
ER membrane protein complex subunit 8

1

0

High-throughput

0.232

Low

266264

ERLN1
Erlin-1

1

0

High-throughput

0.232

Low

335564

NB5R3
NADH-cytochrome b5 reductase 3

1

0

High-throughput

0.232

Low

819035

COPD
Coatomer subunit delta

1

0

High-throughput

0.232

Low

822179

KC1A
Casein kinase I isoform alpha

1

0

High-throughput

0.232

Low

827854

AL7A1
Alpha-aminoadipic semialdehyde dehydrogenase

1

0

High-throughput

0.232

Low

847378

SSRD
Translocon-associated protein subunit delta

1

0

High-throughput

0.232

Low

902378

COPZ1
Coatomer subunit zeta-1

1

0

High-throughput

0.232

Low

961857

REEP5
Receptor expression-enhancing protein 5

1

0

High-throughput

0.232

Low

1026786

PRDX4
Peroxiredoxin-4

1

0

High-throughput

0.232

Low

1058570

GANAB
Neutral alpha-glucosidase AB

1

0

High-throughput

0.232

Low

1065338

AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1

1

0

High-throughput

0.232

Low

1234743

CISD2
CDGSH iron-sulfur domain-containing protein 2

1

0

High-throughput

0.232

Low

1237013

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.232

Low

1243419

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.232

Low

1243800

VP37A
Vacuolar protein sorting-associated protein 37A

1

0

High-throughput

0.232

Low

1246325

MCFD2
Multiple coagulation factor deficiency protein 2

1

0

High-throughput

0.232

Low

1287046

ASTRA
Protein Aster-A

1

0

High-throughput

0.232

Low

1301399

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.232

Low

1310777

PXL2A
Peroxiredoxin-like 2A

1

0

High-throughput

0.232

Low

1310916

ERP44
Endoplasmic reticulum resident protein 44

1

0

High-throughput

0.232

Low

1312437

NDC1
Nucleoporin NDC1

1

0

High-throughput

0.232

Low

1319273

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.232

Low

1329580

RBGPR
Rab3 GTPase-activating protein non-catalytic subunit

1

0

High-throughput

0.232

Low

1336768

APMAP
Adipocyte plasma membrane-associated protein

1

0

High-throughput

0.232

Low

1346889

TM38B
Trimeric intracellular cation channel type B

1

0

High-throughput

0.232

Low

1347109

GPTC2
G patch domain-containing protein 2

1

0

High-throughput

0.232

Low

1348508

TECR
Very-long-chain enoyl-CoA reductase

1

0

High-throughput

0.232

Low

1348515

SERC
Phosphoserine aminotransferase

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024