Protein: DDX51
ATP-dependent RNA helicase DDX51 (EC 3.6.4.13) (DEAD box protein 51)

Gene: DDX51
Organism: Homo sapiens
Interactions: 104
UniProt ID: Q8N8A6

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0003724 - RNA helicase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1089750

ILF3
Interleukin enhancer-binding factor 3

2

20

High-throughput

0.776

High

287053

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

20

High-throughput

0.691

High

985246

RL10A
Large ribosomal subunit protein uL1

1

13

High-throughput

0.691

High

1008799

RED1
Double-stranded RNA-specific editase 1

1

20

High-throughput

0.691

High

1111419

DGKZ
Diacylglycerol kinase zeta

1

1

High-throughput

0.691

High

1331046

DDX21
Nucleolar RNA helicase 2

1

16

High-throughput

0.691

High

1331057

RL36
Large ribosomal subunit protein eL36

1

7

High-throughput

0.691

High

1331026

TF3C2
General transcription factor 3C polypeptide 2

2

0

High-throughput

0.679

High

372586

MYC
Myc proto-oncogene protein

3

20

High-throughput

0.633

High

208313

RRP8
Ribosomal RNA-processing protein 8

2

6

High-throughput

0.628

High

447224

NPM
Nucleophosmin

2

13

High-throughput

0.628

High

841402

RBM34
RNA-binding protein 34

2

20

High-throughput

0.628

High

904934

MECP2
Methyl-CpG-binding protein 2

2

16

High-throughput

0.628

High

1006555

SRPK2
SRSF protein kinase 2

2

20

High-throughput

0.628

High

1037558

RL18A
Large ribosomal subunit protein eL20

2

4

High-throughput

0.628

High

1057807

RL18
Large ribosomal subunit protein eL18

2

8

High-throughput

0.628

High

1219026

RSBN1
Lysine-specific demethylase 9

2

1

High-throughput

0.628

High

1260518

NOL8
Nucleolar protein 8

2

1

High-throughput

0.628

High

1331034

ZN512
Zinc finger protein 512

2

3

High-throughput

0.628

High

1331052

TAP26
Thyroid transcription factor 1-associated protein 26

2

1

High-throughput

0.628

High

1331053

H2AW
Core histone macro-H2A.2

2

11

High-throughput

0.628

High

1088452

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

20

High-throughput

0.618

High

1331038

GRWD1
Glutamate-rich WD repeat-containing protein 1

1

13

High-throughput

0.618

High

169260

CASQ2
Calsequestrin-2

3

2

High-throughput

0.609

High

1199138

PKHO1
Pleckstrin homology domain-containing family O member 1

2

0

High-throughput

0.602

High

1161544

IF16
Gamma-interferon-inducible protein 16

2

14

High-throughput

0.584

High

546988

FGF3
Fibroblast growth factor 3

2

14

High-throughput

0.574

High

935424

FGF8
Fibroblast growth factor 8

2

14

High-throughput

0.574

High

396517

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

768652

RFA3
Replication protein A 14 kDa subunit

2

11

High-throughput

0.558

High

1254652

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.553

High

1331055

HECD1
E3 ubiquitin-protein ligase HECTD1

1

20

High-throughput

0.553

High

191710

MAGB2
Melanoma-associated antigen B2

1

10

High-throughput

0.536

High

288703

NPM3
Nucleoplasmin-3

1

13

High-throughput

0.536

High

290635

SURF6
Surfeit locus protein 6

1

7

High-throughput

0.536

High

338904

CBX6
Chromobox protein homolog 6

1

5

High-throughput

0.536

High

428864

RLA0
Large ribosomal subunit protein uL10

1

10

High-throughput

0.536

High

686274

RL13
Large ribosomal subunit protein eL13

1

9

High-throughput

0.536

High

785297

RL4
Large ribosomal subunit protein uL4

1

11

High-throughput

0.536

High

824234

RL13A
Large ribosomal subunit protein uL13

1

11

High-throughput

0.536

High

833141

MNDA
Myeloid cell nuclear differentiation antigen

1

14

High-throughput

0.536

High

855137

NOP2
28S rRNA

1

12

High-throughput

0.536

High

859904

RL28
Large ribosomal subunit protein eL28

1

3

High-throughput

0.536

High

913542

KIF11
Kinesin-like protein KIF11

1

1

High-throughput

0.536

High

960798

RL15
Large ribosomal subunit protein eL15

1

4

High-throughput

0.536

High

985767

RL11
Large ribosomal subunit protein uL5

1

5

High-throughput

0.536

High

1099162

SRSF5
Serine/arginine-rich splicing factor 5

1

20

High-throughput

0.536

High

1099437

SRSF6
Serine/arginine-rich splicing factor 6

1

20

High-throughput

0.536

High

1120244

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

16

High-throughput

0.536

High

1281419

ZN467
Zinc finger protein 467

1

2

High-throughput

0.536

High

1331030

FGF13
Fibroblast growth factor 13

1

14

High-throughput

0.536

High

1331031

NEIL1
Endonuclease 8-like 1

1

4

High-throughput

0.536

High

1331033

ZN668
Zinc finger protein 668

1

4

High-throughput

0.536

High

1331040

RBM4
RNA-binding protein 4

1

15

High-throughput

0.536

High

1331042

REXO4
RNA exonuclease 4

1

3

High-throughput

0.536

High

1331043

SENP3
Sentrin-specific protease 3

1

8

High-throughput

0.536

High

1331048

ABC3C
DNA dC->dU-editing enzyme APOBEC-3C

1

4

High-throughput

0.536

High

1331050

GAR1
H/ACA ribonucleoprotein complex subunit 1

1

3

High-throughput

0.536

High

1331056

ABT1
Activator of basal transcription 1

1

8

High-throughput

0.536

High

1331058

NGN3
Neurogenin-3

1

2

High-throughput

0.536

High

1331059

BACE2
Beta-secretase 2

1

1

High-throughput

0.536

High

1331027

MY18A
Unconventional myosin-XVIIIa

1

0

High-throughput

0.513

High

1331037

SORT
Sortilin

1

0

High-throughput

0.513

High

657267

KALM
Anosmin-1

1

4

High-throughput

0.489

High

1042031

LMNB2
Lamin-B2

1

12

High-throughput

0.489

High

1127430

FGFP1
Fibroblast growth factor-binding protein 1

1

5

High-throughput

0.489

High

1331035

CC140
Coiled-coil domain-containing protein 140

1

1

High-throughput

0.489

High

129258

MEN1
Menin

1

9

High-throughput

0.479

High

157617

CTRO
Citron Rho-interacting kinase

1

17

High-throughput

0.479

High

190997

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

8

High-throughput

0.479

High

223180

PRC1
Protein regulator of cytokinesis 1

1

7

High-throughput

0.479

High

331147

KI20A
Kinesin-like protein KIF20A

1

20

High-throughput

0.479

High

404226

GCR
Glucocorticoid receptor

1

20

High-throughput

0.479

High

487537

PARP1
Poly [ADP-ribose] polymerase 1

1

15

High-throughput

0.479

High

504927

H2AB2
Histone H2A-Bbd type 2/3

1

8

High-throughput

0.479

High

589168

RFA2
Replication protein A 32 kDa subunit

1

14

High-throughput

0.479

High

695950

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

11

High-throughput

0.479

High

770229

RL22
Large ribosomal subunit protein eL22

1

4

High-throughput

0.479

High

810221

RL3
Large ribosomal subunit protein uL3

1

8

High-throughput

0.479

High

831068

CCNF
Cyclin-F

1

8

High-throughput

0.479

High

937817

FOXA1
Hepatocyte nuclear factor 3-alpha

1

8

High-throughput

0.479

High

979063

RS6
Small ribosomal subunit protein eS6

1

12

High-throughput

0.479

High

979994

H4
Histone H4

1

11

High-throughput

0.479

High

1045525

TF65
Transcription factor p65

1

7

High-throughput

0.479

High

1140565

KIF14
Kinesin-like protein KIF14

1

7

High-throughput

0.479

High

1290589

ZCH18
Zinc finger CCCH domain-containing protein 18

1

11

High-throughput

0.479

High

1331025

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

9

High-throughput

0.479

High

1331028

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1331029

KAT6A
Histone acetyltransferase KAT6A

1

20

High-throughput

0.479

High

1331032

DDRGK
DDRGK domain-containing protein 1

1

10

High-throughput

0.479

High

1331036

RING2
E3 ubiquitin-protein ligase RING2

1

15

High-throughput

0.479

High

1331041

PCGF6
Polycomb group RING finger protein 6

1

13

High-throughput

0.479

High

1331047

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

11

High-throughput

0.479

High

1331049

AKIP
Small ribosomal subunit protein mS38

1

4

High-throughput

0.479

High

1331051

TLS1
Splicing factor C9orf78

1

1

High-throughput

0.479

High

1331054

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

14

High-throughput

0.479

High

162948

TERT
Telomerase reverse transcriptase

1

0

Small-scale

0.460

High

601769

HMGA1
High mobility group protein HMG-I/HMG-Y

1

3

High-throughput

0.445

High

756271

MCM7
DNA replication licensing factor MCM7

1

10

Small-scale

0.445

High

1239878

CAVN1
Caveolae-associated protein 1

1

1

High-throughput

0.445

High

1331039

ZSA5A
Zinc finger and SCAN domain-containing protein 5A

1

5

High-throughput

0.445

High

1137857

TNIP1
TNFAIP3-interacting protein 1

1

20

High-throughput

0.437

High

1331044

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.437

High

1331045

ANLN
Anillin

1

8

High-throughput

0.437

High


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Last updated: 11Aug2025