Protein: SYT2
Synaptotagmin-2 (Synaptotagmin II) (SytII)

Gene: SYT2
Organism: Homo sapiens
Interactions: 129
UniProt ID: Q8N9I0

Gene Ontology (top 5):
GO:0001786 - phosphatidylserine binding
GO:0005509 - calcium ion binding
GO:0005544 - calcium-dependent phospholipid binding
GO:0005886 - plasma membrane
GO:0014059 - regulation of dopamine secretion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

599585

SYT1
Synaptotagmin-1

2

18

High-throughput

0.811

High

1205937

C2CD5
C2 domain-containing protein 5

1

19

High-throughput

0.691

High

129084

SYT5
Synaptotagmin-5

1

17

High-throughput

0.665

High

261693

VAMP4
Vesicle-associated membrane protein 4

2

4

High-throughput

0.606

High

364579

TRFE
Serotransferrin

2

1

High-throughput

0.606

High

673333

MIP
Lens fiber major intrinsic protein

2

1

High-throughput

0.606

High

943593

S35A1
CMP-sialic acid transporter

2

1

High-throughput

0.606

High

1021990

BNIP2
BCL2/adenovirus E1B 19 kDa protein-interacting protein 2

2

1

High-throughput

0.606

High

1238340

AQP10
Aquaporin-10

2

2

High-throughput

0.606

High

1238350

SNAB
Beta-soluble NSF attachment protein

2

1

High-throughput

0.606

High

791775

HD
Huntingtin

2

9

High-throughput

0.588

High

146052

CLD4
Claudin-4

2

0

High-throughput

0.580

High

207464

LAT
Linker for activation of T-cells family member 1

2

0

High-throughput

0.580

High

506123

ITAM
Integrin alpha-M

2

0

High-throughput

0.580

High

964840

PMP22
Peripheral myelin protein 22

2

0

High-throughput

0.580

High

1022735

MALL
MAL-like protein

2

0

High-throughput

0.580

High

1136872

TSPO2
Translocator protein 2

2

0

High-throughput

0.580

High

1139801

PLPP4
Phospholipid phosphatase 4

2

0

High-throughput

0.580

High

1219457

ZNT8
Proton-coupled zinc antiporter SLC30A8

2

0

High-throughput

0.580

High

1230208

ORML3
ORM1-like protein 3

2

0

High-throughput

0.580

High

1238326

STON2
Stonin-2

1

4

Small-scale

0.561

High

1184808

FA2H
Fatty acid 2-hydroxylase

2

1

High-throughput

0.553

High

1238334

S35A4
Probable UDP-sugar transporter protein SLC35A4

2

1

High-throughput

0.553

High

49641

RHG10
Rho GTPase-activating protein 10

1

1

High-throughput

0.536

High

508104

FGFR1
Fibroblast growth factor receptor 1

1

4

High-throughput

0.536

High

876704

BRPF1
Peregrin

1

1

High-throughput

0.536

High

957526

VLDLR
Very low-density lipoprotein receptor

1

3

High-throughput

0.536

High

968323

ROR1
Inactive tyrosine-protein kinase transmembrane receptor ROR1

1

6

High-throughput

0.536

High

1051825

EI2BA
Translation initiation factor eIF2B subunit alpha

1

4

High-throughput

0.536

High

1057144

KANK1
KN motif and ankyrin repeat domain-containing protein 1

1

2

High-throughput

0.536

High

1238327

MADD
MAP kinase-activating death domain protein

1

4

High-throughput

0.536

High

1238343

APBA2
Amyloid-beta A4 precursor protein-binding family A member 2

1

2

High-throughput

0.536

High

1238347

NAA15
N-alpha-acetyltransferase 15, NatA auxiliary subunit

1

3

High-throughput

0.536

High

1238356

E41L5
Band 4.1-like protein 5

1

1

High-throughput

0.536

High

686006

ARRB2
Beta-arrestin-2

1

0

High-throughput

0.513

High

1157340

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

1

0

High-throughput

0.513

High

1238322

CAMKV
CaM kinase-like vesicle-associated protein

1

0

High-throughput

0.513

High

1238323

PI42C
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma

1

0

High-throughput

0.513

High

1238351

ADNP
Activity-dependent neuroprotector homeobox protein

1

0

High-throughput

0.513

High

1238349

THS7B
Thrombospondin type-1 domain-containing protein 7B

1

0

High-throughput

0.493

High

120002

AP3B1
AP-3 complex subunit beta-1

1

2

High-throughput

0.489

High

216546

SAHH2
S-adenosylhomocysteine hydrolase-like protein 1

1

3

High-throughput

0.489

High

257658

ANR17
Ankyrin repeat domain-containing protein 17

1

1

High-throughput

0.489

High

263737

PR40A
Pre-mRNA-processing factor 40 homolog A

1

3

High-throughput

0.489

High

324844

M4K4
Mitogen-activated protein kinase kinase kinase kinase 4

1

3

High-throughput

0.489

High

331314

CHK2
Serine/threonine-protein kinase Chk2

1

1

High-throughput

0.489

High

788050

AF9
Protein AF-9

1

3

High-throughput

0.489

High

827976

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

1

High-throughput

0.489

High

834433

EI2BB
Translation initiation factor eIF2B subunit beta

1

4

High-throughput

0.489

High

850834

AFF3
AF4/FMR2 family member 3

1

2

High-throughput

0.489

High

897273

CSN2
COP9 signalosome complex subunit 2

1

1

High-throughput

0.489

High

974500

ENL
Protein ENL

1

3

High-throughput

0.489

High

1025657

EI2BE
Translation initiation factor eIF2B subunit epsilon

1

3

High-throughput

0.489

High

1032728

AP3B2
AP-3 complex subunit beta-2

1

1

High-throughput

0.489

High

1043106

CUL4A
Cullin-4A

1

3

High-throughput

0.489

High

1043459

CUL4B
Cullin-4B

1

3

High-throughput

0.489

High

1048872

BOP1
Ribosome biogenesis protein BOP1

1

1

High-throughput

0.489

High

1109054

CHD9
Chromodomain-helicase-DNA-binding protein 9

1

1

High-throughput

0.489

High

1147509

UTP25
U3 small nucleolar RNA-associated protein 25 homolog

1

1

High-throughput

0.489

High

1160943

CTR9
RNA polymerase-associated protein CTR9 homolog

1

1

High-throughput

0.489

High

1174507

UB2R2
Ubiquitin-conjugating enzyme E2 R2

1

1

High-throughput

0.489

High

1190680

HDGR2
Hepatoma-derived growth factor-related protein 2

1

1

High-throughput

0.489

High

1238328

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

1

High-throughput

0.489

High

1238335

SAHH3
Adenosylhomocysteinase 3

1

3

High-throughput

0.489

High

1238338

DCAF5
DDB1- and CUL4-associated factor 5

1

2

High-throughput

0.489

High

1238341

LENG8
Leukocyte receptor cluster member 8

1

1

High-throughput

0.489

High

1238342

NP1L3
Nucleosome assembly protein 1-like 3

1

1

High-throughput

0.489

High

1238348

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

1

High-throughput

0.489

High

1238353

CSN7B
COP9 signalosome complex subunit 7b

1

1

High-throughput

0.489

High

1238355

CWC22
Pre-mRNA-splicing factor CWC22 homolog

1

1

High-throughput

0.489

High

1238358

EI2BG
Translation initiation factor eIF2B subunit gamma

1

3

High-throughput

0.489

High

1238364

CSN7A
COP9 signalosome complex subunit 7a

1

1

High-throughput

0.489

High

1238366

AFF4
AF4/FMR2 family member 4

1

2

High-throughput

0.489

High

1238367

EI2BD
Translation initiation factor eIF2B subunit delta

1

4

High-throughput

0.489

High

1238369

GPTC8
G patch domain-containing protein 8

1

1

High-throughput

0.489

High

1238370

CSN3
COP9 signalosome complex subunit 3

1

2

High-throughput

0.489

High

1238371

SMG5
Nonsense-mediated mRNA decay factor SMG5

1

1

High-throughput

0.489

High

1238373

ARI1
E3 ubiquitin-protein ligase ARIH1

1

4

High-throughput

0.489

High

235956

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

6

Small-scale

0.457

High

240099

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

5

High-throughput

0.445

High

497309

TAU
Microtubule-associated protein tau

1

8

High-throughput

0.445

High

887898

CD81
CD81 antigen

1

1

High-throughput

0.445

High

1047164

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

12

High-throughput

0.445

High

657999

ACADL
Long-chain specific acyl-CoA dehydrogenase, mitochondrial

3

0

High-throughput

0.342

High

1166266

TM107
Transmembrane protein 107

2

0

High-throughput

0.316

High

1238321

T229B
Transmembrane protein 229B

2

0

High-throughput

0.316

High

1238339

CKLF3
CKLF-like MARVEL transmembrane domain-containing protein 3

2

0

High-throughput

0.316

High

1238346

FUND2
FUN14 domain-containing protein 2

2

0

High-throughput

0.316

High

1238363

CC167
Coiled-coil domain-containing protein 167

2

0

High-throughput

0.316

High

165697

SET1A
Histone-lysine N-methyltransferase SETD1A

1

0

High-throughput

0.279

Low

176242

PPM1G
Protein phosphatase 1G

1

0

High-throughput

0.279

Low

203305

FIBP
Acidic fibroblast growth factor intracellular-binding protein

1

0

High-throughput

0.279

Low

265541

ERN1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

0

High-throughput

0.279

Low

299419

UBXN7
UBX domain-containing protein 7

1

0

High-throughput

0.279

Low

422549

CENPB
Major centromere autoantigen B

1

0

High-throughput

0.279

Low

792240

MTHR
Methylenetetrahydrofolate reductase

1

0

High-throughput

0.279

Low

833477

RBM25
RNA-binding protein 25

1

0

High-throughput

0.279

Low

1061019

NOLC1
Nucleolar and coiled-body phosphoprotein 1

1

0

High-throughput

0.279

Low

1166128

CWC27
Spliceosome-associated protein CWC27 homolog

1

0

High-throughput

0.279

Low

1167154

RBP10
Ran-binding protein 10

1

0

High-throughput

0.279

Low

1168239

CERS6
Ceramide synthase 6

1

0

High-throughput

0.279

Low

1184909

CSN6
COP9 signalosome complex subunit 6

1

0

High-throughput

0.279

Low

1192655

UB2Q1
Ubiquitin-conjugating enzyme E2 Q1

1

0

High-throughput

0.279

Low

1229942

MIER1
Mesoderm induction early response protein 1

1

0

High-throughput

0.279

Low

1236213

CA052
UPF0690 protein C1orf52

1

0

High-throughput

0.279

Low

1237133

PAF1
RNA polymerase II-associated factor 1 homolog

1

0

High-throughput

0.279

Low

1238324

TM10A
tRNA methyltransferase 10 homolog A

1

0

High-throughput

0.279

Low

1238325

LEO1
RNA polymerase-associated protein LEO1

1

0

High-throughput

0.279

Low

1238329

RTF1
RNA polymerase-associated protein RTF1 homolog

1

0

High-throughput

0.279

Low

1238330

CSN5
COP9 signalosome complex subunit 5

1

0

High-throughput

0.279

Low

1238331

ARK2N
Protein ARK2N

1

0

High-throughput

0.279

Low

1238332

EAF2
ELL-associated factor 2

1

0

High-throughput

0.279

Low

1238333

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

0

High-throughput

0.279

Low

1238336

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.279

Low

1238337

BOD1
Biorientation of chromosomes in cell division protein 1

1

0

High-throughput

0.279

Low

1238344

CYBC1
Cytochrome b-245 chaperone 1

1

0

High-throughput

0.279

Low

1238345

CSN4
COP9 signalosome complex subunit 4

1

0

High-throughput

0.279

Low

1238352

WDR55
WD repeat-containing protein 55

1

0

High-throughput

0.279

Low

1238354

GPBL1
Vasculin-like protein 1

1

0

High-throughput

0.279

Low

1238357

IFT46
Intraflagellar transport protein 46 homolog

1

0

High-throughput

0.279

Low

1238359

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.279

Low

1238360

GPTC2
G patch domain-containing protein 2

1

0

High-throughput

0.279

Low

1238361

WDR70
WD repeat-containing protein 70

1

0

High-throughput

0.279

Low

1238362

DCA16
DDB1- and CUL4-associated factor 16

1

0

High-throughput

0.279

Low

1238365

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

1

0

High-throughput

0.279

Low

1238368

DACH1
Dachshund homolog 1

1

0

High-throughput

0.279

Low

1238372

EXOG
Nuclease EXOG, mitochondrial

1

0

High-throughput

0.279

Low

1238374

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

0

High-throughput

0.279

Low

1061501

CUL7
Cullin-7

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024